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  • BDD Moderators: Keif’ Richards

Suboxone snorting tenique

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Correct me if I'm wrong, which I often am, but isn't there an opiate blocker in subutex? I was under the impression that if you took it orally then it would work, but if you snorted or shot it up then the blocker would take affect and you would feel nothing. This could just be a drug user myth, but I always thought that was the pharmaceutical company's way of making it "abuse proof".
 
you are wrong....you are thinking of naloxone wich is in suboxone not subutex....snorting it does have a higher ba, but it stays in the body less amount of time....in my opinon check out the mega thread
 
No, the subutex(buprenorphone) still works no matter what ROA you use, even if there is nalaxone in it(nalaxone is the "opiate blacker"). But, in case you didn't know, subutex doesnt even contain nalaxone, only suboxone does. And that doesnt matter anyway, because buprenorphine has a higher binding affinity to your receptors than nalaxone does therefore the nalaxone is virtually inactive no matter how you take the drug suboxone(with subutex you dont even have to worry about that anyway because there is no nalaxone). But, buprenorphine itself actually acts as an "opiate blocker" because it has the highest binding affinity of almost all opiates, therfore, when you take bupe, no other opiate you take will be able to bind to your receptors because bupe has such a stong binding affinity.

But to answer the OP's question....

the Bioavailability of subutex(bupernorphine) sublingually(NOT orally, you cannot take it orally, it will BARELY work) is ~55%.

the BA of subutex(bupe) intranasally is ~70%...much better than sublingually.

the BA of subutex(bupe) rectally is ~70-80%....works very well and I reccomend...in small doses.

the BA of subutex(bupe) IV is obviously 100%....and NO, it will not cause you to go into withdrawals if you IV bupernorphine/subutex/suboxone. I do it EVERY day.

In fact suboxone/subutex/bupe/whatever....should always be taken in very small doses lower than 4 mg's...prefferably lower than 2 mg's...it works better this way because it leaves receptors open for bupes metabolite norbupernorphine which is a FULL AGONIST meaning it can get you high or atleast feel buzzed and good....but only at the low doses. Otherwise, at high doses, the bupe with fill ALL the receptors up leaving no room for the metabolite norbupe.

I personally only take 0.5 mg's doses of suboxone and it gives me a nice little euphorical high every day. But when I tak doses over 2 - 4 mg's I feel nothign but normal and a headache.

Long story short OP......if you snort your subutex it will work faster and hit you stronger, and probably feel better. but I reccomend only doing this if your only taking very small doses.....otherwise there is really no point, if you take high doses, no matter how you take the drug, it will simply make you feel normal, and you will get no other beneficial effects.
 
The creators of suboxone put the nalaxone in suboxone and said that the nalaxone made the drug "abuse proof" because anyone who tried to crush the pill up and snort it or IV it would immediately go into withdrawals because of the nalaxone....thus making it seem like a safer drug and consequently the FDA believed this and classified it as schedule III instead of schedule II like methadone, making the drug much easier to prescribe, thus making the creators of suboxone more rich.

but the truth is that the nalaxone does absolutely nothing because the bupe has a stronger binding affinity than nalaxone so no matter what route of administration you use, the bupe will ALWAYS outcomepete the nalaxone for the receptors.

It was basically a ploy to fool the FDA into making the drug more easily prescribed so they can sell more of it to fill there pockets with cash.

I have been IV'ing and snorting suboxone for a long time and not once have I had a negetive effects, in fact it works MUCH better than sublingually.
 
Feel free to ask ANY questions....im quite well researched onthe subject. And have plenty of personal experience.
 
Thanks, so if I could cut down to .5 I would get more of a buzz out of it? Sound
 
Thank you jamesbrown that makes a lot of sense. It's funny what pharma companies do to see drugs without regard for their actual effects. Is naloxone bad for you in any way even though it's inactive or does it pass pretty easily? Seems like even if it doesn't block the effect it or some of it's metabolites might be active somehow in the body. Basically I'm asking what any negative effects of naloxone might be when used in the context of bupe?
 
agreed. well put james. i also take suboxone/subutex often, and have noticed much of the same. although, when i take large doses (8-24mg) i do still get a "buzz" feeling sometimes...especially when snorted. snorting the subutex definately gave me more of a buzz than subling ever did, but it gave me a god awful headache about an hour later...so i guess you just have to weigh the pros and cons when using and abusing! good luck op!
 
FordRiverFailed said:
Thank you jamesbrown that makes a lot of sense. It's funny what pharma companies do to see drugs without regard for their actual effects. Is naloxone bad for you in any way even though it's inactive or does it pass pretty easily? Seems like even if it doesn't block the effect it or some of it's metabolites might be active somehow in the body. Basically I'm asking what any negative effects of naloxone might be when used in the context of bupe?
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The nalxone shouldnt have any noticeable effects for the most part. Unless your taking very high doses of suboxone(like anything over 8 mg's in my opinion) than you might get a headache from it but thats pretty much it.

Of course, if your allergic to nalaxone than you will have more severe reactions to it but that is obviously a rare occurence.

But, if your not allergic to nalaxone and your only taking low doses of suboxone like I suggested, you should feel/have ZERO effects from it. I for one have never had any negative effects from the nalaxone when taking my low doses....allthough sometimes when I would randomly decide to take a high dose of suboxone to see what would happen, the nalaxone would give me a headache and the bupernorphine would only make me tired. I don't reccomend it.

Low doses...low doses....low doses...
 
short snort so that it stays in your nasal cavity, muich better absorbtion through your mucus membranesthen if it goes into your stomach or lungs.

alos,i hear that if you take a 1/4 shot of bacardi and sawish it around in yout mouth, it makes the absorbtion sublingually go up to 70% (bbetter than snorting). somethiing to do with thinning something in your mouth. i shoot my subutex to make it last. sometimes i wont take it for a day and then ahoot 4mgs (subutex not suboxon, although i have shot suboxone w no ill effects) and it had me noddin pretty hard. popped 1mg xanax 20 mins before too.
 
Thank you for the input, subs are apparently a very complex pharmaceutical. Handy to have around though of course. This is slightly off topic but after reading this thread I kind of wondered if this scenario might work. Here goes:

You have friend A, they're overdosing on opiates. You have an 8mg Suboxone (with naloxone) on hand. Will the naloxone reverse the effects of the opiate (Heroin for example) and save their life? I know they will be thrown into withdrawal immediately, but could the naloxone allow them to survive if they are near death from Heroin?
 
FordRiverFailed said:
Thank you for the input, subs are apparently a very complex pharmaceutical. Handy to have around though of course. This is slightly off topic but after reading this thread I kind of wondered if this scenario might work. Here goes:

You have friend A, they're overdosing on opiates. You have an 8mg Suboxone (with naloxone) on hand. Will the naloxone reverse the effects of the opiate (Heroin for example) and save their life? I know they will be thrown into withdrawal immediately, but could the naloxone allow them to survive if they are near death from Heroin?
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First of all....ONCE AGAIN...the nalaxone NEVER is active and NEVER does anything when taken with bupe(suboxone).

Therefore you should rephrase your question to...

"Will the bupernorphine reverse the effects of the opiate...."

And yes, if your friend "A" is overdosing, than giving them suboxone will throw all the opiates off there receptors because of the BUPE not the nalaxone. Remember, the nalaxone is ALWAYS inactive...does nothing...might as well forget about it(unless your allergic).

But, I have never heard of any research done on this particular instance, but I would assume that the bupe throwing the opiates off the receptors would reverse the effects of the overdose and prevent them from dying or atleast help increase there heart rate and respiration. they would obviously be in HORRIBLE precipitated withdrawals and would DEFINITELY need medical attention as soon as possible......but I do believe that the suboxone could be used as a helpful tool when someon is overdosing.

Also, you mentioned an 8 mg suboxone pill, I dont know how much it would take.....each scenario would probably call for a different amount of suboxone.

But, also, remember, I dont know any of this for a fact, im just going on what I DO know about suboxone and how it affects the human brain/body in relation to other opiates, etc...

***If your friend ever DOES overdose, I woudl reccomend calling 911 before you even consider giving him/her suboxone. the dispatchers may tell you to give it to him'her but probably woul tell you to wait for the paramedics. but if your in a situation where you know for a fact our friend will die from respiratory failure or soemthing(overdose) and the ambulance wont get there in time, I would definitely give him/her the suboxone because as far as I can tell it should pull them out of the overdose, and throw them into a withdrawal....and withdrawal is better than overdose anyday.
 
crizzle said:
short snort so that it stays in your nasal cavity, muich better absorbtion through your mucus membranesthen if it goes into your stomach or lungs.

alos,i hear that if you take a 1/4 shot of bacardi and sawish it around in yout mouth, it makes the absorbtion sublingually go up to 70% (bbetter than snorting). somethiing to do with thinning something in your mouth. i shoot my subutex to make it last. sometimes i wont take it for a day and then ahoot 4mgs (subutex not suboxon, although i have shot suboxone w no ill effects) and it had me noddin pretty hard. popped 1mg xanax 20 mins before too.
Click to expand...

Actually I believe that using alcohol to help increase the BA of suboxone sublingually works very well, but snorting still works better. They are atleast about equal BA's but from my experience snorting suboxone has a higher BA than SL(w/ alcohol).

Also...you guys should try snorting suboxone after you have snorted a tiny drop of 97% ethyl alcohol. I mean a TINY amount, but still enough to where it coats the inside of your nostrils with the alcohol vapors. This increases the BA of intranasal to around 85-90% in my opinion.
 
Yes thank you for the information. I understood the nalaxone is inactive it was a typo I meant to say bupe. nalaxone is just so fun to type. This situation was PURELY hypothetical and of course I would call 911. What I was referring to was a situation where help would be very far away. I don't have too many friends who are heavy opiate abusers, so I'm not really worried but ya never know, could come in handy some day.
 
james -

funny as it is, but I have had friends use suboxone to reverse the overdose of a friend.
it worked, but it left them with horrible withdrawals as one would assume...
 
i have been on suboxone for a couple of months now and i dont get a buzz at all whatsoever!! before i was prescribed it i had snorted it before and it didnt give me a buzz then either to me it just makes me feel normal . do some people actually get a buzz of it? just curious
 
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