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Suboxone Help

H

Hotdamn

Greenlighter
Joined
Jul 6, 2014
Messages
9
I have a question on beginning my subs for those that can help.

I am on about 700mg of roxycodone per day. After reading through this forum I learned through Robert to slowly begin my induction at 2mgs an hour until I reach my daily dose, afterwards I will begin a taper.

I am to take my first dose while under mild WD's, 26 on the Cows. My question is am I on to high a dose of Roxy to avoid precipitated withdrawal. Is it ok to start at 700mg as long as I am at 26 or will I still go through percipitated withdrawal. I have read conflicting responses on this some have said you need to be at a much lower dose to avoid them and others say as long as you get a 26 on the Cows then it makes no difference how big your habit is. Please help me.
 
Your score on an opiate withdrawal assesment chart doesn't necessarily mean you will avoid precipitated wd. There is every chance that your oxycodone usage will be too high for buprenorphine to replicate the activity at the opiod receptors that it's giving you due to the ceiling dose. This would mean precipitated wd (i.e. buprenorphine won't cover your habit and you will need to use methadone as a maintainence drug).

I'm not too hot on my opiate equivalencies and it depends on the route of administration you are using but off the top of my head that sounds like too big a habit to be covered by buprenorphine. Personally I would start by trying 16mg and then going up from there, unless you are wasting a huge amount of what you are using it won't be too much.

Give it a try but don't be surprised if no matter how much bupe you take it isn't enough. If this is the case you will need to use methadone then reduce.
 
I appreciate your response but that is not what precipitated withdrawal is. Precipitated Withdrawal is when you either do not wait long enough or have too much of the opiate you take in your system that when you take suboxone it pushes it off and cause an intense withdrawal. This is what I am wondering if will still happen because of my 700mg a day roxycodone habit.
 
Perhaps I should have worded things differently, your case is a complicated one.

You have two immediate risks, straight precipitated withdrawal from using buprenorphine too quickly, but you are also at a significant risk of buprenorphine's ceiling dose not being enough to stimulate your receptors sufficiently to match the oxycodone you are using and you will then be stuck in a situation where your receptors are full of buprenorphine but there is a gap in the stimulation the receptors were receiving before and what they can get from a ceiling dose of bupe. Technically this would be normal withdrawal rather than precipitated but the end result for you will be the same, a period whereby your receptors are flooded with bupe but not being stimulated enough. Call it what you will, you won't be worrying about what it's name is if it happens.

It's a complicated process as buprenorphine is a mixed antagonist/agonist at one receptor and a pure antagonist at another. Even on the receptor where it has agonist activity it only continues up to (I believe) 4mg.

So irrespective of the fact you might have waited long enough to take the buprenorphine, THAT DOES NOT MEAN YOU WILL BE SAFE FROM WITHDRAWAL.

I would be a hell of a lot more sure than you are about whether bupe will be enough to match your habit before diving in and trying to use it otherwise you could become caught in a nasty situation. My immediate reaction is that you can't cover that level of use with bupe, but likke I say I'm not so hot on my opiate equivilancies and there are many other complicating factors.

Just don't be thinking that as long as you wait long enough you will be fine because that's not necessarily the case.
 
Yeah man 700mg is no joke bro. How long have you been taking 700mg? I agree with omen, I don't think the subs can cover that much if you've been taking that much for awhile. A healthy dose of methadone sure but idk about subs cause of the ceiling. I'd taper to maybe 240 mg over a week or so but that's just me. Just be sure before u take the sub bro, that'll really suck if u go into acute wd...
Edit: it comes out to 54mg of Bupe to cover 700mg oxy, that's over the ceiling dose I believe...
 
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So say I get my use down to around 300 mg or lower per day for a week and then begin next week is that a better idea and will that cover me?
 
Or can I do it for a shorter time. I want to get on suboxone as soon as possible. I do not have the luxury of being able to go on methadone due to no one knowing about this and me trying to do this on my own.
 
With 300mg I think you'll be right at the ceiling dosage, do u really wanna gamble like that bro? That's a much better idea than going head on with 700mg though. What dose of sub are u gonna start at? I saw u said u were gonna go 2mg at a time? Is it from a dr or you doing it on ur own? I'm not sure how you'd dose that much sub to be most effective. That's some shit you don't wanna fuck with fo' sho' lol...
 
Yes it is from a doctor. I just want to slowly introduce the suboxone into my system. I can try and taper lower what would you suggest?
 
300mg=24mg Bupe, that's like right at the ceiling bro, I've heard people say it's a little higher but that's tempting fate IMO. I'd try to get it down as low as possible man, -240mg. But dude I don't think u want to ummm, like right now you got 700mg a day floating through u. Tomorrow say u take 240mg, I don't think you can just take the sub like u now have a 240mg a day habit, u know what I mean? Idk how to convert that, but I'd say like 5 days on 240 mg should be good but I'm far from a dr lol. I use subs when I run outta oxy too( right now lol) so I know what your talkin about for sure, but your on a helluva lot more of the ox than I am so I can't imagine what the precipitated wd will be like on 700mg bro. You gotta be real fuckin careful to avoid those dts brother. Since your doing it on your own you gotta figure out how to dose that much sub, like starting at 2mg would be an awful idea I think. That would throw u into wd I think, I'm not sure if u can just throw 24mg in your mouth either. This much shit is gonna take much more than a week to taper off of bro. I'm not the best writer but do you see what I mean? Your still gonna have to taper the sub but it's not a panacea. It takes awhile to taper and not wd at all, from the sub I mean...
Ohhh it is from a dr. Cool, dude just ask him. He's gonna know for sure, I'm just using equivalency charts and little but if experience I have in taking the subs the same way you want to take them. But to be totally safe I would think your dr knows best. I thought u were doing it on your own and buying the sub off the street like I do lol.
 
Where are you getting your conversions from. What i see is that 1 mg sub is equivalent to 30 mg oxy.
 
I saw something totally diff. Let me see if I can find the chart, I'm sure it's not 30x1 bro lol I can guarantee that much
 
Medcalc.com bro 300=24
A little less than 10x1 which sounds right to me. Figure it out if you got all u need bro. 1mg sub does not equal 30mg of oxy no way. Where ru get... Forget it lol.
 
Thx ramblin, that's about what I thought. Any idea how he should dose 24 mg? I've never gone near that with my dosing so I don't wanna give bad info. Like should he start with 12,14,16 ? Then dose like 2mg at a time like a smaller starting dose?
 
I don't know but I'm fairly confident you won't be able to cover a 700mg oxycodone habit with buprenorphine. 24mg just about covered a gram or so of UK street gear IV a day for me, and the quality of UK street gear is appalling at the moment. The good stuff is probably 40% purity still, but that would have been average before the drought a few years ago.

I didn't have my dosage titrated at all, it was quite dangerous really. The doctor just asked how many bags of gear a day I was using and I think they give you 4mg for every bag you're using or something. I was just straight up given 24mg to take in one go first time round, but I did say I thought I might need near ceiling dosage. I would say if you're genuinely taking 700mg a day via any reasonably efffecient method and have been for a while then it's safe to dive in straight at that dosage because the chances of even 32mg covering them is pretty low.

Technically you should induct 2mg at a time but if it was my habit at that level and I was starting to go in to withdrawal, I would try at least 16mg immediately, more likely 24mg even. I would also be expecting the bupe to probably not hold me completely even at 32mg which will suck because you will then have a load of bupe stuck to your receptors for days and be in withdrawal. It will take a fair period for enough bupe to be metabolised before you can start breaking through it with a different opiate.
 
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