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Suboxone - Experienced - This is what Hell Feels Like

PureLife

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Background- I'm prescribed suboxone at 16mg a day. On this specific day i had used heroin. I used very small doses of heroin up to an hour prior to my IV suboxone dose of 3mg. I was beginning to feel opiate withdrawal and thought that shooting the suboxone would provide relief and maybe even I'd feel G good. I was so FUCKING wrong and ignorant. It turns out it was WaY to early to administer the Suboxone, let alone fucking shoot it

30 seconds after I.V administration- I feel an instant chill, my stomache churns, my pupils dialate the size of the moon. The worst part about it was that i felt dizzy. This dizziness scared the shit out of me, like my equilibrium was tossed off just a tad bit

5 minutes after the injection- I'm sweating insanly. I'm soaked in sweat. Everything around me seems distorted, almost bigger. My pupils looked like i was tripping on a heavy dose of mdma or lsd. They were at the biggest i''ve ever seen them. I was soaked in sweat, yet freezing cold. My body physically hurt all over. I was depressed. i didn't want to even open my mouth, let alone speak.

45min. after administration------- I was beginning to feel a little better. My vision was beginning to come back to normal. The sweating subsided, and the i was also beginning to communicate more with people. It was obvious at this point that there was a noticable amount of confusion during the initial 45 minutes of the withdrawal i went through.


All said, i seriously thought something really bad was going to happen to me. It felt worse than opiate withdrawal, this vision distorrion and equilibrium changes are what scared me the most. It felt different from dizziness. It almost felt like my brain swelled or something heh. I don't know what else to say, so if i left out anything of question, I'll be more than happy to answer questions.



-m.
 
The devil in the details

First, let me preface this response by noting that this is an extremely dangerous drug. Especially for those who are using, have used recently, or intend to use in the near future, opioids.

Subutex=buprenorphine
Suboxone=buprenorphine+naloxone
Naloxone=the devil in the details

"Naloxone blocks the effects of opioids such as morphine, codeine, and heroin. If Suboxone is injected, naloxone will block the effects of buprenorphine and lead to withdrawal symptoms in a person with an opioid addiction. When administered under the tongue as directed, naloxone will not affect the actions of buprenorphine"*

*Source-Drugs.com

Why, in hell's name the pharmaceutical industry would create a drug such as this? I'll never understand. In theory, from what I have read, it is supposed to create an environment in which the opioid user has a diminished capacity to use opiates effectively. I have used these pill's after a night's partying, as directed, sublingually and have experienced rapid onset withdrawal
 
oxyidated said:
Why, in hell's name the pharmaceutical industry would create a drug such as this? I'll never understand. In theory, from what I have read, it is supposed to create an environment in which the opioid user has a diminished capacity to use opiates effectively.

Because the naloxone is only active IV, but not when taken sublingually, it makes diversion/abuse of suboxone much less likely/desirable. This means that patients can be trusted with multiple doses without the same risk of diversion as methadone.

Likewise, the bupe is only a partial agonist, and thus is MUCH less likely to lead to full respiratory depression in the case of overdose.
 
Sounds rough man, ive been through it a few times myself. You really have to be feeling sick as shit before you dose the suboxone or else it will really precipitate some nasty WD.

Just a few weeks ago i took two days off from suboxone and got a half gram of dope had some fun that night and all the next day. waited about 24 hours, was feeling kinda shitty so i took the suboxone and got all those same efects you listed, just in a slower onset since i didnt IV it.

Highly unpleasant
 
wow... so how soon after the precipitated withdrawals come on can you safely take another dose of suboxone? or does the experience make you want to wait a day just to be on the safe side?
 
^its just the action of that initial dose pulling any remaining opiates off of the receptors. You can take a second dose and its not going to make you any sicker or anything. That first dose is what does it.
 
Hense why Suboxone is not something to abuse. It works perfectly well under the tounge, but if you must, as a general rule for the average person, it takes about 12-16hrs. before the naloxone doesn't affect you after a dose of oxycodone, hydromorphone, or oxymorphone. It takes around 24hrs. after a full dose of Heroin. It takes about 36hrs. or more after using Methadone and this is given you haven't had the drug built up in your system.

However, as I have said, this is an average chart. Someone earlier in this post mentioned withdrawal syndrome 24hrs. after using Heroin.

My chart is based on my own experiences as well as those of about 15 of my friends and fellow dope heads. One of them in particular is very sensitive to naloxone and felt its effects after waiting the full 36hrs they want you to wait before you go into the clinic/office.
 
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^
the blocking of heroin , oxycodone etc is not caused by the minute amounts of naloxone when taken sublingually but by the burpenorphine itself

only 3% of the naloxone gets absorbed when the suboxone is taken sublingually and after a few hours only trace amounts are left in the body
 
Piper methysticum said:
Hense why Suboxone is not something to abuse. It works perfectly well under the tounge, but if you must, as a general rule for the average person, it takes about 12-16hrs. before the naloxone doesn't affect you after a dose of oxycodone, hydromorphone, or oxymorphone. It takes around 24hrs. after a full dose of Heroin. It takes about 36hrs. or more after using Methadone and this is given you haven't had the drug built up in your system.

However, as I have said, this is an average chart. Someone earlier in this post mentioned withdrawal syndrome 24hrs. after using Heroin.

My chart is based on my own experiences as well as those of about 15 of my friends and fellow dope heads. One of them in particular is very sensitive to naloxone and felt its effects after waiting the full 36hrs they want you to wait before you go into the clinic/office.

How used are you or your friends used to switching between heroin/suboxone?

I've been experimenting more this summer and have gotten high several times on heroin after taking low doses of suboxone 8-12 hours earlier.

I usually try to wait as long as I can, but I've had no problem taking suboxone 12-18 hours after last dosing on H. Obviously in both these situations it depends how much heroin you're dosing with and how much suboxone.

I think once you get used to switching your body adapts to it better?
 
oxyidated said:
First, let me preface this response by noting that this is an extremely dangerous drug. Especially for those who are using, have used recently, or intend to use in the near future, opioids.

Subutex=buprenorphine
Suboxone=buprenorphine+naloxone
Naloxone=the devil in the details

"Naloxone blocks the effects of opioids such as morphine, codeine, and heroin. If Suboxone is injected, naloxone will block the effects of buprenorphine and lead to withdrawal symptoms in a person with an opioid addiction. When administered under the tongue as directed, naloxone will not affect the actions of buprenorphine"*

*Source-Drugs.com

Why, in hell's name the pharmaceutical industry would create a drug such as this? I'll never understand. In theory, from what I have read, it is supposed to create an environment in which the opioid user has a diminished capacity to use opiates effectively. I have used these pill's after a night's partying, as directed, sublingually and have experienced rapid onset withdrawal



this is partially wrong, when you i.v. suboxone, the naloxone WILL NOT block the effects of the bupe. buprenorphine has a higher affinity for the mu opioid receptors than naloxone and will take control of the receptors no matter what MOA is used. It is the buprenorphine that knocks you into immediate withdrawal when you dose the sub too soon, not the naloxone. yes, the naloxone is only active via i.v., but the bupe still overpowers it b/c of its higher affinity for the opioid receptors. the only reason they put naloxone in those pills is to scare ppl away from abusing them, which doesnt work anyways. i'm not trying to say your wrong or get on to you or anything, just trying to correct the statement a little.
 
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I dont think the naloxone is totally ineffective tho, when i used to inject them, if i did more than like 8mgs i would start to get that cold feeling coming up my back. If you have ever been injected with an antagonist while addicted, then you know what im talking about. But it never sends me into precipitated WD, it just makes me feel kind of shitty for an hour. I was never big into shooting suboxone tho, its gross as shit.

Being on 16mgs a day i can either wait 3 days to get high off my normal dose of dope, or i can spend triple the amount of $ and punch through 24 hours after my last dose of bupe. I think it gets easier switching back and forth from bupe to a full agonist the more you do it. I know ive had some pretty dicey experiences when i first got on suboxone.
 
Surprised nobody has mentioned snorting Suboxone. I know people who take it that way all the time instead of sublingual. Not that I am recommending it. I just know it is similar to the oral route in that the naloxone is not active.
 
oxyidated said:
"Naloxone blocks the effects of opioids such as morphine, codeine, and heroin. If Suboxone is injected, naloxone will block the effects of buprenorphine and lead to withdrawal symptoms in a person with an opioid addiction. When administered under the tongue as directed, naloxone will not affect the actions of buprenorphine"*
*Source-Drugs.com

I had no idea that if you take it under your tounge the naloxone wont effect the bup? I was always told that it works, but doesn't effect the (sorry for my bad pharmalocialy lol sp?) opoid agnosit thing in your brain.. Does it work the same if you snort it?
 
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