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  • BDD Moderators: Keif’ Richards | negrogesic

Suboxone and Wellbutrin?

I'm on clonodine for insomnia at night. I used to be on modafanil but it didn't help at all with my adhd and I also found it to be physically unpleasant. I'm very sensitive to uppers except for dexedrine apparently. Not totally true, I felt it the dex for the first couple of days. I think I broke some of my receptors with Kratom abuse and tinapetine abuse. When I was abusing prescription opiods and alcohol (I stopped drinking about a decade ago, I am an alcoholic) other stuff still worked normally. Something in the past year has changed though and the only thing really, is my intense several month tinapetine bender that I went to detox for in feb.
 
Do not take tinapetine (or phenibut). It's waaaaaay not worth it. I'm always afraid someone is going to read my posts and go try it. It's really, really evil (and expensive)
 
Bupropion is very potent enzyme blocker (mostly cyp2d6) with enzimes being inhibited even for month after last dose. Maybe this Has something to do with it. Don't know if something else, in my opinion is IS very weak DRI and weak - moderate NRI. This maybe cause buprenorphine less noticable but for example tramadol (not weak SNRI + be real real dopamine boosting effects) is working as one of a few opioids while being treated with buprenorphine. Ofc wellbutrin absolutely diminishes any tram. mu-opi related effects to 0.
 
idontremember said:
Do not take tinapetine (or phenibut). It's waaaaaay not worth it. I'm always afraid someone is going to read my posts and go try it. It's really, really evil (and expensive)
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It is horrible, super-short acting opioid with effects on dopamine (raising dopamine) independent of opioid related dopamine raising effects. It's like little opioid cocaine.
 
Anecodote, Wellbutrin was fantastic not just for reducing my relationship with nicotine, but also reduced my interest in other quick gratification compulsions of ADHD in a way amphetamine preparations never did.

I love buproprion. But perhaps this is what is happening to you but undesired?
 
Madness said:
Yeah dexedrine has less levo IIRC? It's like 75 percent to 25 instead of Adderall 50 50? I could be talking out my ass but, if depression is the main concern I don't see why Wellbutrin would be nice. You named that it works better than it did in the past too. All things to bring up with your doctor who knows me than me

Edit : dex might be all dextro, Adderall has levo, either way dex is stronger and less jittery IME
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Correct me if I'm wrong I thought Dexedrine was a dead brand and it's Zenzedi now?

Regardless Dexedrine is or was, like Zenzedi entirely dextro-amphetamine

Adderall is 75% dextro-amphetamine and 25% levoamphetamine (stabilized as four different salts)

In my experience Adderall packs a far greater punch than dextro-amphetamine alone- however dextro-amphetamine is much less harsh on the back half. I like how d-amph is very subtle and gentle, but I see the benefit of Adderall to those who suffer from ADHD "burn out" cycles of lethargic depression. That l-amph will get you out of bed and singing in the shower at 6am
 
idontremember said:
I'm on clonodine for insomnia at night. I used to be on modafanil but it didn't help at all with my adhd and I also found it to be physically unpleasant. I'm very sensitive to uppers except for dexedrine apparently. Not totally true, I felt it the dex for the first couple of days. I think I broke some of my receptors with Kratom abuse and tinapetine abuse. When I was abusing prescription opiods and alcohol (I stopped drinking about a decade ago, I am an alcoholic) other stuff still worked normally. Something in the past year has changed though and the only thing really, is my intense several month tinapetine bender that I went to detox for in feb.
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Dextro-amphetamine is often noted to be "smoother" subjectively. I interpret this and others do as well that it is more subtle, less strength to the euphoria but no agitation, zoomin around like a robot, muscle clenching etc. Just a really nice clean sense of "everything is just a bit easier to organize my thoughts around, plan, and prioritize".

I like to think that it essentially takes my very best high effort un-medicated days and makes every day like that
 
Tianeptine sulfate was on clearweb maybe still in like 1000mg or more powder, as Coaxil that is 12,5mg sodium or natrium english-croatian tomato/tomato ;)

that shit is true short acting BS and it fucks with something I just didn't have time to explore it as I saw threads about people having probs later with ORT, methadone and bupe.

ADHD- dextroamphetamine is best stim I tried as here it is almost impossible to find but Concerta works great as I burn it in 5 days than i have 10 days recovery till next rx which is every 15 days

Vyvansse is lisdexamphetamine or like ibuprofen lysine which is absorbed when in small intestine to not get rec.

I tried with atomoxetine with concerta and even was taking it a month and maybe it was placebo but I got it for free so I tried with 50-75mg daily, it worked after couple days in not losing train of thought.

Also Methylphenidate and maybe bupropion is close to but not the same as and will put you in a withdrawal like state as crash and not taking subs at the time..(can be confusing).There is case study with young guy reporting he took 160mg couple days and he couldn't comfort his opioid withdrawal with buprenorphine..I most certain it's Swiss or it is reported there. I will find it maybe it was Croatian. but my memory is very strange maybe better than Terence.

They say Joe Rogan stopped taking DMT and started talking to Terence Howard
 
ĐmantuNJofra said:
Vyvansse is lisdexamphetamine or like ibuprofen lysine which is absorbed when in small intestine to not get rec.
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Lisdexamfetamine is composed like Dexedrine or Zenzedi entirely of the dextrorotary methamphetamine isomer. The molecule is attached to lysine, an amino acid in dietary supplements. Lisdexamfetamine can not enter the brain- and has no subjective physical or psychological effects.

However the magic actually happens in yer blood, not instine. Lisdexamfetamine is a pro-drug, or a drug that is metabolised into the desired mind altering drug. As lysine is needed by the body, your blood recognizes it and rips it off of the dextro-amphetamine leaving essentially Dexedrine in your bloodstream. This is a two fold design that:

1. Is a slow and smooth extended release compound. Blood can only cleave lysine at a certain rate- you can't speed it up or slow it down. The benefit here is it makes Vyvanse 100% predictable and consistent. Adderall XR on the other hand is a capsule with half of the beads digesting and releasing instantly, the other half take longer for the coating to dissolve. Ideally six hours, however conditions like diet, metabolism, acidity of urine can play a role in shortening or lengthening Adderalls activity, and its intensity. I hated Adderall XR, it was like a non negotiable redose. I'd always be crashing from the first dose and getting agitated and angry- then dose two kicks in and now I'm angry but faster.

2. It's not really worth the effort to abuse it. Since lisdexamfetamine is cleaved into lysine and dextro-amphetamine in the bloodstream, baking soda makes no difference. Snort it and it will trickle down your throat, enter the stomach- and enter the blood stream. But it won't enter the mucus membrane. Boof it, and you just wasted a Vyvanse.

Can't be extracted or converted to dexamph easily. And if you eat ten pills, your blood reaches a standstill. There's too much Lisdexamfetamine to cleave, so the Lisdexamfetamine starts a "que" floating around waiting to be made active. Essentially you likely will get some nice long lasting euphoria... until you realize you've put so much Lisdexamfetamine in your blood that the high won't get any higher... but it'll last a lot lot longer whether you want to be awake for three days or not lmao

Loved Vyvanse. So smooth, barely even noticed it. A great ADHD med should not give you euphoria, it should simply level the playing field with as little intrusion or change in your normal personality as possible
 
Oh and fun fact, there is an approved prescription medication called Benzamphetamine which is a pro-drug like Vyvanse but it releases slowly both pure dextrorotary amphetamine as well as well as pure dextrorotary METHAMPHETAMINE.

Currently it is strictly for very serious fourth line treatment binge eating disorders

However with the popularity of other weight loss or eating moderating meds, I reckon Big Daddy Pharma will scoot it over to ADHD soon
 
ĐmantuNJofra said:
High dose MPH and opioid witjdrawal
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I would politely say to 99% of psychiatrists and to 100% of " 'experts' that approve 'war on drugs' " or anyone who thinks that turning people into juvenile morons (including juvenile morons that support "The Experts") to, well - go fuck yourselves!

Nothing personal @ĐmantuNJofra it's just that paper you cited invoked some fckd up memories and made my blood boil. Fuckem all!!!

Continue as though I never interupted the thread. Off to calm down with few songs of The Beat Fleat...
 
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