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  • BDD Moderators: Keif’ Richards

Strongest opioid and Opiates

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K'd-OUT-in-AZ said:
Levorphanol is a great opioid. Very underrated and should be used more often for pain. The shit lasts forever and is very potent. I had gotten a hold of a bottle of 100 2mg pills and I made that shit last. I shot the shit out of many of those pills. 2mg is equivalent to 15mg of Morphine. So x7.5 stronger.
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I wish I could get a hold of one of those bottles with 100 Levorphanol pills in it. That would be some awesome times............:)
 
lordreven333 said:
bump lol people need to see this if they haven't alot of information or opioids and opiates ok

can someone explain the difference between opioids and opiates. yes you could look it up some people won't I did and its been a while.
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Opiates are naturally occurring alkaloids contained in the resin of the opium poppy, primarily morphine, codeine, and thebaine. Opioids are synthesized from these opiates, known as semi-synthetics. As example, oxycodone is synthesized from thebaine, heroin from morphine and Dihydrocodeine from codeine. Fully synthetic opioids are not derived from opiates. They are made to mimic the effects of opiates. Includes Tramadol, propoxyphene & fentanyl.
 
plenty of opiates are stronger than the ones you listed, as you have just scratched the surface. Fentanyl is to my experience one of the more potent opiates, but also creates less euphoria, more nausea, and alot more breathing issues. oxycodone and hydrocodone have stronger cousins that are metabolized from those drugs called Oxymorhpone(opana) and hydromorhpone(dilaudid)
 
K'd-OUT-in-AZ said:
No, Levorphanol is x7.5 more potent than Morphine 2mg=15mg or 4mg=30mg same thing.
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How do you figure? Even your link here states 10 mg IV/IM morphine = 2 mg IV/IM levorphanol. Ten divided by two is five, meaning five times more potent. Orally, it's 7.5x more potent.

I'm going to repost this:

I had a book years ago that I took from my aunt (who is a dentist) that she had from dental school. It was a Pharmacology book and it had a chart that compared various opiates through the IV route.

Here is how it was:

Morphine IV 10 mg =

Heroin 5 mg (2x more potent than morphine) (Morphine prodrug)
Hydromorphone 1.5 mg (7x more potent than morphine)
Fentanyl 0.1 mg (100x more potent than morphine)
Oxymorphone 1 mg (10x more potent than morphine)
Levorphanol 2 mg (5x more potent than morphine)
Oxycodone 20 mg (morphine is 2x more potent)
Meperidine (Demerol) 75 mg (morphine is 7.5x more potent)
Buprenorphine 0.5 mg (20x more potent than morphine)

So the list would actually go something like this:

Fentanyl
Buprenorphine
Oxymorphone
Hydromorphone
Levorphanol
Heroin
Morphine
Oxycodone
Demerol

I'm not including methadone on the list because I've never seen any real data for it the IV route. My gut feeling however tells me it's more potent than oxycodone both orally and intravenously. Methadone is an highly potent narcotic, while oxycodone is more unstable as it is quite potent orally, but loses much of it's potency IV. It's slightly more potent than morphine orally, but as you can see - morphine is 2x more potent intravenously. If I had to guess though, I'd say that 15 mg of methadone = 10 mg morphine IV.
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Any new thoughts anyone?I have a question about soma and mixing it with opiates and benzo's First does soma and opiates mixed get you really high tell me what you know also I've heard that mixing soma with benzo's is also a strong high.Is any of that true?
 
lordreven333 said:
Any new thoughts anyone?I have a question about soma and mixing it with opiates and benzo's First does soma and opiates mixed get you really high tell me what you know also I've heard that mixing soma with benzo's is also a strong high.Is any of that true?
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Yea Soma+opies is a good time, but be aware of your tolerance. I dont know about benzos and somas.
 
I have kinda a high tolerence to hydrocodone It use to be 10mg would be more than enough But last time it took about 20-30mg and there was 3 grams of apap total would you say that's a high tolerence or??
 
It's not a high tolerance, but its not a contest either.

There's no such thing as APAP tolerance, you don't want to be taking 3 grams (3000mg) of APAP on a regular basis.
 
lordreven333 said:
I have kinda a high tolerence to hydrocodone It use to be 10mg would be more than enough But last time it took about 20-30mg and there was 3 grams of apap total would you say that's a high tolerence or??
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your tolerance is still relatively low; keep it there. also you shouldn't worry about that much APAP, as it really only gets bad at 4g/day, but it's also not the best thing for your body but we all do drugs here so :|

i did 75mg of oxycodone tonight because i couldn't find any oxymorphone (my baby). i really enjoy the roxy high as it feels real clean and some what energizing; opana kicks my ass and i like it =D
 
3g in 24 hours is okay; it's safe to take 4g in 24 hours if spaced out properly (1g every 4-6 hours) but to take 3g at once is not so good, think of your poor liver trying to process all that APAP at once.

To take 3g in one go daily is gonna put some at least strain on your liver.. everyone's liver handle things differently; am sure most would be fine but you don't want to be the one ending up with liver failure! If in doubt, CWE, it's easy...

Back on topic - remifentanyl is the strongest I've seen used in humans (twice as strong as fent) but carfentanyl kicks its ass by the looks of things!!
 
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