strange idea regarding withdrawal

[Mr Crowley]

So I was researching drug withdrawal and noticed that the effects are pretty much the exact opposite of whatever drug has been used. Are there any drugs with only negative effects? Would it be possible to use these drugs on very low doses for an extended period of time with minimal effects and build a tolerance? If you built up enough of a tolerance to have withdrawal would it be enjoyable?
I couldn't find any information on this and I think you could effectively get a long lasting high without actually being on drugs when you put yourself into withdrawal by doing this.
Or maybe it's not possibly, does anyone have any thoughts or information on this!?

 

[PotatoMan]

Homeless ------> BDD

 

[jammin83]

lol. Pretty funny idea, have fun getting depressed enough for long enough that the withdrawal is actually euphoric.

Oddly enough, there was a stage of my benzo withdrawal that was actually pretty euphoric, sort of, I guess. My pupils were like saucers and I kind of felt like I was tripping on acid. Pretty weird. Benzos made me terribly depressed though.

I don't think it would work though.

 

[Speed King]

In theory, nice idea.

 

[Kittycat5]

I dont even understand the question tbh. How would building any tolerance make withdrawal euphoric? I understand what jammin is saying but overall withdrawal is terrible.

 

[Mr Crowley]

drug withdrawal has the opposite effect to the drug.
you would be on a drug with undesirable effects, with a massive tolerance, and only dose enough to keep the tolerance and not feel the effects. then you can trigger w/d whenever you want to get high and you won't be on any drugs.

does it make sense now?

 

[Kittycat5]

Ahh got it. So like taking naltrexone, stopping and getting opiate euphoria. Not sure that really happens though.

 

[MadMike17]

I like halfway see what your trying to say. Build up a tolerance to something, stop using it and try to get high. But when you said "triggering w/d when you want to get high and you won't be on any drugs." I'm not sure how you can get high and not be on any drugs?

 

[Mr Crowley]

you would essentially be training your brain to function normally with lower levels of dopamine/serotonin/etc..(probably just one) without ruining your brains ability to produce or release the chemicals. I don't know very much about biology or chemistry but if you found the right drug/drugs I think it should be possible.

and then you should feel exquisite whilst off the drug and normal while on it.
(kind of like with methadone with h addicts and feeling alright on it and then feeling terrible when you're off it, but in reverse)

any info would be appreciated I couldn't find any.

 

[hexagon]

I'm assuming your line of logic is that, because abusing dopamine agonists like stimulants downregulates dopamine receptors in your synapses and causes depression upon withdrawal, a side-effect of habitually using dopamine antagonists like antipsychotics would be euphoria upon withdrawal. Is that correct?

If so, you need to remember that your brain already has a baseline for healthy homeostasis. Artificially lowering the dopamine in your synaptic cleft would upregulate dopamine receptors in your brain, but the process of reversing that wouldn't be experienced as pleasurable at all, because it would necessarily requires that there be no surplus of dopamine in your synapses.

It would be analogous to breaking a bone for the gradual relief you'd experience while it was healing.

 

[Mr Crowley]

would it possibly work differently with serotonin? like I said, I've never studied biology or chemistry so I am very limited in my understanding of this. thanks for the info!