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Stopping semi long term 2ce use.. Any health issues to expect?

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SoDizZzY

Greenlighter
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Aug 10, 2011
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Title pretty much says it, iv been using close to daily for about half a year mostly through liquid dosing. Iv heard 2ce is bad for the heart, though iv never been worried about an irregular heartbeat or anything of the sort in my time using. My vision seems different though in a strange way when sober. ANy input?
 
man, that's a lotta 2c-e. What was you're typical dose?

The only putative toxicity i'm aware of is production of free radicals during metabolism. This could theoretically be mitigated by high intake of antioxidants, but no one really knows if this is a legitimate problem or if antioxidants actually help in regards to free radicals. I would think the more pressing issues would be the psychological ones that inspired that much use, and usage of any psychedelic that frequently could cause psychological problems. I doubt stopping would cause any acute problems, other than boredom with normal life ;)
 
Of course, as a research chemical, nobody can give you definite answers. Not that many people have taken it as much as you have to begin with, and even fewer of them have reported back on perceived health problems. There have been some fatality scares in recent months, as a few deaths have been reported as being caused by massive 2C-E overdoses, but I'm not aware of any that were reliably confirmed and at least two deaths that were initially blamed on 2C-E were found to be the result of a mislabeled batch of a much more potent drug being sold as 2C-E (see this thread for details). Long story short: there's no conclusive evidence that 2C-E can cause death or long-term physical damage on its own.

AFAIK there's no conclusive proof of this (then again, there's virtually no conclusive proof on any of the effects of 2C-E), but there is anecdotal evidence that heavy 2C-E use might cause lasting stomach discomfort, and that snorting 2C-E is probably pretty rough on your nose. I went through a couple grams of -E in a couple months a while back, dosing 2-4 times a week, and the nausea/stomach irritation I got as a constant side effect of 2C-E lingered for a couple months. I still have some minor issues with indigestion/acid reflux, nothing an OTC acid reducer and the occasional Tums can't handle though, and that is certainly at least in part due to poor diet.

Lingering visual distortions are definitely to be expected after using any psychedelic so heavily for so long. Using other drugs will often make those distortions flare up, even months or years later - especially cannabis and MDMA, in my experience. It's nothing to worry about unless you still have significant distortions while completely sober, at least 3 months after your last use of any psychedelic, and the distortions are severe enough to interfere with your daily life; at that point, you might be experiencing HPPD (hallucinogen persisting perception disorder) or flashbacks. In the vast majority of cases, the distortions fade over a few weeks or months, although in many cases they never really go away 100%. I still notice some familiar colorful swirls and geometric patterns in the corner of my eye, or if I stare at a wall long enough, or while my eyes adjust to a sudden change in light levels, but if I don't look for it I don't really notice it. I like to think that my brain is just more creative at filling in those visual gaps where my eyes aren't providing anything useful.

As for the heart concerns, I think that's mainly just that people find it stimulating and have an elevated heart rate while they're actually tripping on it. If you haven't noticed any troubling heart symptoms either while using 2C-E or since you stopped, I wouldn't worry. If you have health insurance, or live in a civilized country where you don't need insurance to get basic medical treatment, you can talk to a doctor and maybe get an EKG just to be sure your heart is good and healthy.


If the lingering visuals don't fade on their own, you can look into HPPD treatment, but in most cases all they can really do is try to lower your stress levels (either through therapy/lifestyle adjustment, or good ole' drugs, typically benzos) and help you learn to cope. As for your heart and overall health, I'd say try and schedule a check-up/physical exam with a doctor in the not-too-distant future, but as long as the doc says you're in good health, there's no sense worrying about it.
 
Hey I hope you don't mind if I ask but why did you do it so long? Did you have any goal? And did it work out as you wanted?
 
I used 2C-E 2-3 times a week for about 2 months last year. Nowhere near as much as you but I can say the only lasting issues I experienced were that my perception was quite "off" for a good month or so after I stopped taking it so often. Visual distortions and a general change in mental perception - however that died down until it was no longer apparent.

The only real "negative" effect is that I don't desire to trip very often like I did then since I overdid it, but honestly I think that's just the excitement of trying psychedelics wearing off into a more level-headed approach to their use. So not so negative after all.
 
Just for fun man I moved out of state due to being arrested and luckily getting the case dropped due to a few errors on the cops part even though i was guilty as fuck hah. Anyway parents sent me away with my uncle who kicked me out and i ended up getting arrested again and convicted. So now its been about a year on probation and i cant really do much so iv been fillin the gap with rcs. i dont really feel much different at all in fact i still kinda feel under some kind of influence but its positive. plus my vibrant vision is a real plus. what a coo drug hah
 
I've recently invested in a stock of many intensely psychadelic RCs for my treasure chest. I plan on significant long-term dosing, including hallucinogens from all three families (psychadelic, dissociative, deliriant). I will research the effects on my clinically diagnosed undifferentiated schizophrenia. Previously, I have extensively experimented with all forms of drugs, and have found that hallucinogens are effective at coping and understanding, even benefiting and controlling my "illness", despite their apparent role in the early onset of my predisposed condition (by means of a short lasting case of HPPD, after which I began to experience while sober delusions, true hallucinations, and negative symptoms). I believe it's just a strange and different thought process system, not necessarily a disease. 2C-E is among the compounds in my arsenal.
 
When I ordered a gram of 2c-P I took it every day for little over a month
started off small and worked my way up, halfway thru the month I was taking 12mg doses, and smoking booster doses off foil.


I'm fine, no residual visual effects, definately got "hppv" like symptoms for weeks after eating shrooms 3 days in a row however, I was having "flashbacks" for weeks.
 
Hmm.. I had HPPD for 3 or 4 months (albeit from LSD), so it's a little odd hearing that this compound's residual effects wear off so quickly. Everyone has different bodies of course, so I wonder how I will be affected. We will see haha.
 
!!4iV4HF9R34g, if you don't mind me asking...what deleriants are you working with, and are you intending on using those regularly as well?

i'm not flaring up in an anti-deleriant-based psychonauticism rant, i promise. i don't see those chemicals, and certainly not the deleriant plants, as being evil (or useless to development) at all. I love my datura garden :D though i've never eaten them, i just meditate beside them and commune...perhaps someday when the time is right though we will fully meet.

sorry to derail
 
Well, I've got a few places in the canyons where I know Datura grows. I was considering buying Mandrake or Hesbane, or even Atropa Belladonna (I've done it before). But nothing is bought yet, so the Datura is my definitive answer.
I do plan to use the deliriants regularly, perhaps even daily dosing of seeds for a (short (relatively)) prolonged period, within my continued dosing of entheogens.
This Deliriant Phase would most likely follow an initial potent Psychadelic Phase, preferably with DOC or 2C-E / 2C-P. (Has anyone anything to say about the decision between these?) This phase, however, will have to follow a potent Natual Psychadelic Phase now, because my RC vendor did indeed ship me a compound; NaHCO3, baking soda!! Oh well though.
The natural phase will be cool. I'm gonna make Yopo! I'll even kill a bird and make a hollow snuff tube, as well as use snail shells as the calcium oxide necessary for the Anadenanthera peregrina to convert the 5-OH-DMT to 5-O-DMT, leaving the chemical makeup of Bufotenine and producing Yopo. (: (Note: Don't let this snuff Yopo (not really Anadenanthera peregrina anymore) come into contact with your stomach acids (usually by swallowing the drip), or it will revert to 5-HO-DMT, inducing much vomiting. (Although pronounced nausea ought to be expected regardless.) I'm getting a large quantity, and these seeds produce intense trips, akin to smoked DMT or Salvia. However, perhaps very small regular use, along with the longer trips of HBWR..
Does anyone have information that would be pertinent to my using Syrian Rue along with Yopo or HBWR? Any health concerns? Thanks.
 
^ don't mix a maoi with hbwr, it could be quite dangerous as hbwr cause vasoconstriction already. Make sure you do some research at least, a simple google search turns up enough info that I wouldn't try it.
 
Thank you; I'll remember that.
Isn't this community exactly for the purpose of obtaining information like this though?
 
indeed, i just don't have the proof to back it up (other than anecdotal reports), some people have used the two successfully for really strong trips, others have felt like they were poisoned, i'd be very careful with your dose and do more research/wait for someone with the pharmacological knowledge before trying it out on yourself, for safety reasons if nothing else. Using an maoi with hbwr is going to make it hit you a lot harder, there are some concerns with the depressant effects on breathing and vasoconstriction. Be cautious about using an maoi with other psychedelics as well.

Your plan for deliriant use is nuts but i'd be interested in hearing how it works out, especially after dropping a 2c on top, I'm not sure if i'd even remember anything and i've had my fair share of diphenhydramine trips.
 
How could one use 2C-E daily? The nausea and come-up is unbearable (though the ensuing trips are amazing)
 
^tolerance, i've taken it 4-5 days in a row, by the end it just feels like you're taking speed, the psychedelic effects stop but there's still stimulation, and the comeup/nausea isn't near as noticeable if you are always redosing. How does one manage to sleep or eat properly is my question, and what kind of doses would be used after months? lol I had to double my dose each day to make it worth it, what a waste but I was bored at the time.
 
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