Explain it by telling somebody to shake somebody's right hand with their left hand.It's amazing how many people on BL just cannot get to grips with the concept of optical isomerism. I mean, it's not of interest to most people.
I discovered some people really struggle with the whole idea of mirror images being different. I have tried and failed to teach this concept. But that may say more about my ability to teach than anyone else's ability to learn.
No, you're a discerning consumer.Am I a terrible person to think that cartel meth is actually really good?
Well that depends.I have never messed with Cartel meth or the homemade stuff, what is the difference?
I try to be as correct and complete as necessary to answer the question.Wow, that was a truly impressive answer
Pseudoephedrine Is a secondary alcohol and it's reduced by removal of the hydroxyl group. So I shouldn't have said amination by reduction because it was already an amineGood Morning!
I really wouldn´t call this an impressive answer. At least not the chemistry part.
@snmfmy
If pseudoephedrine is used as starting material in a methamphetamine synthesis the reaction is NOT a reductive amination. Instead a benzylic hydroxy is swapped for a hydrogen so it is a reduction. Have a look at the pseudoephedrine molecule. The nitrogen (with a methyl attached to it) is already in place. One just needs to remove that OH group.
Reductive amination (aka reductive alkylation) is the exchange of a carbonyl oxygen for a nitrogen (eg. ammonia or methylamine). This is what happens with P2P as a precursor.
Also using elemental lithium from batteries doesn´t involve lithium hydride. It is a kind of birch reduction utilising in situ generated ammonia.
And when aluminium metal is used to reduce an intermediate imine (formed from P2P and methylamine) the metal is NOT a catalyst. It´s a source of electrons for the reduction of the imine.
This is called a dissolving metal reduction (mercury is needed to break passivation of the aluminium metal so it can react).
Cheers
Wow, I am impressedGood Morning!
I really wouldn´t call this an impressive answer. At least not the chemistry part.
@snmfmy
If pseudoephedrine is used as starting material in a methamphetamine synthesis the reaction is NOT a reductive amination. Instead a benzylic hydroxy is swapped for a hydrogen so it is a reduction. Have a look at the pseudoephedrine molecule. The nitrogen (with a methyl attached to it) is already in place. One just needs to remove that OH group.
Reductive amination (aka reductive alkylation) is the exchange of a carbonyl oxygen for a nitrogen (eg. ammonia or methylamine). This is what happens with P2P as a precursor.
Also using elemental lithium from batteries doesn´t involve lithium hydride. It is a kind of birch reduction utilising in situ generated ammonia.
And when aluminium metal is used to reduce an intermediate imine (formed from P2P and methylamine) the metal is NOT a catalyst. It´s a source of electrons for the reduction of the imine.
This is called a dissolving metal reduction (mercury is needed to break passivation of the aluminium metal so it can react).
Cheers
Were you a consultant on the television show, Breaking Bad? Lol. Ephedra grows in Afghanistan: The Taliban has claimed it will eradicate the opium fields. Can wild ephedra be used to make a new cash crop product; methamphetamine or some variation of it?There is a catalytic hydrogenation of pseudoephedrine directly to methamphetamine? You got reference for this? Because I think ephedrine needs to be
converted to chloroephedrine before being catalytically hydrogenated to methamphetamine. So NOT really direct.
Thank you for the link@Jnowhere
Not a consultant for BB but some (luckily legal) chemistry background!
These links might answer your question:
https://www.vice.com/en/article/7kv...-afghanistan-is-turning-up-all-over-the-world
https://www.emcdda.europa.eu/public...-supplier-of-ephedrine-and-methamphetamine_en
https://www.unodc.org/unodc/en/pres...-expanding-rapidly-as-heroin-trade-slows.html
? Because I think ephedrine needs to be converted to chloroephedrine before being catalytically hydrogenated to methamphetamine. So NOT really direct.
The original poster has to be Trolling. Who would make their username that??? Moreover? P2P was/is always superior in all aspects, and it is not a subjective issue. Impurities, yield, crystallisation? There is no comparison. Most cartels though use ephedrine making the o.p. almost certainly a Troll. We know what they use ephedrine both by forensic chemistry and seizure reports in Mexico. They import barrels of powdered ephedrine from China. P2P gives a superior product but cartels only care about cost-effectiveness & profit margins.No you don't get it. The switch from pseudo to P2P means you will always get shit. If you've been doing meth less than 10 years please do not join the discussion because you haven't done good old american pseudo meth. Here's a good way to tell if u have pseudo meth, you only need about 3/4 of a gram for the entire weekend. Snorting, not smoking.
Yes, it's lithium hydride because there's no aluminum in lithium battery foil. You can use anhydrous ammonia, pseudoephedrine, and lithium.@snmfmy
1. LAH is common abbreviation for LithiumAluminiumHydride. No ammonia involved.
2. If by sodium hydroborate you mean sodium borohydride (NaBH4) then NO this reagent won´t be able to perform the reduction of pseudoephedrine to methamphetamine.
1. There is no HgCl. It´s either HgCl2 (Mercury(II)chloride) or Hg2Cl2 (Mercury(I)chloride).
2. Elemental aluminium is spent during the reaction. Whenever one substrate is reduced (here pseudoephedrine), some other material will be oxidised. In this case aluminium.
Also there will be elemental mercury (Hg) in the waste stream. Again a chemical change because initially you feed in a salt of mercury.
What do you mean by recycling process?
Condensation product of ketone and amine is called an IMINE.
I'd take MDA over methamphetamine any dayI don't think their is a definitive best precursor or best route. People who make the stuff only care about one thing.
Profit.
I've always believed that the best product is what the customer wants and I don't know anyone who has sampled both 4MAR and methamphetamine who thought the latter was better. But I freely admit, I don't really mix in those circles so I can only base my opinion on what 14-15 people have told me. Others might have been left with a totally different impression.
People will just come up with novel synthesis where controlled Precursors are generated in situ and reacted away.Well L-PAC is almost certain to become the next pre-precursor for methamphetamine production. It's mostly produced in India using bioreactors.
I just think methamphetamine is really harmful. I've seen it harm friends. I've never seen it make someone's life better.
It does frighten me that it's so synthetically simple. I only mention L-PAC because it just underlines the fact that legal control is nigh on impossible. Another approach is needed. Now I'm not saying I know what that alternative is, but I just sense it's the rational thing to do.