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Stimulants stomach issues from oral amphetamines

B

bampot

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Joined
Oct 29, 2011
Messages
23
So I've been taking speed a few days a week for a few months now...that is, amphetamine sulphate powder (not meth, not clinical, seems to be an exclusively European thing). Decent stuff, but still "street speed", so certainly impure to some extent. I don't binge or anything - I eat/sleep/exercise exactly as normal, just use it to feel a bit buzzed and energised. Probably comparable to 60mg or so of adderall daily.

Anyway, I've noticed that after, say, the third day of using it I start to get an extremely unpleasant feeling in my upper abdomen. Not acidic or cramping, just a nasty constant bloated aching feeling. This will still be lingering the next day, but after a day or two off it always goes away.

I'm wondering what this is caused by. Is it likely to be a direct result of the stuff irritating my stomach lining? Or over-basification of the stomach? Or is it more likely to be a pharmacological effect (I've heard for example that amphetamines can reduce blood flow to the stomach)? Then again perhaps it is due to something the product is cut with?

I intend to investigate this soon by trying the rectal route (insufflating wouldn't really tell me anything due to the drip)...that would at least tell me if it was a pharmacological problem or not. Just interested though - has anyone else experienced this? I'm assuming it doesn't commonly occur with clinical dexedrine or racemic mixtures, or else they wouldn't so widely prescribed. Then again, perhaps with some people it does happen, and it is just my personal digestive system that reacts badly?

Does anyone else regularly swallow street amphetamine sulphate, and if so, do you ever have stomach problems? Does anyone ever have any problems from taking adderall or dexedrine?

Bit of a vague rambling question - basically any enlightenment on possible causes of gastric reactions from amphetamines (or cutting agents) will much appreciated.

PS - One thing that might be complicating this is that I also take a daily omeprazole (prilosec...a proton pump inhibitor) for gastric reflux....
 
i had the same problem the day after the one and only time i took aderall. I was kinda curious too but seeing as im not gunna take it again i didnt worry to much about it
 
Can you acetone wash it? I realize it's not a hydrochloride salt and I'm having a brain fart right now, you'll have to excuse me, I forget if it works with sulphates, but I think it does.

Acetone wash would rid your amphetamines of impurities, which should help.

stimulants usually fuck up my GI too, and I have existing chronic pain in my GI. I prefer taking my stims rectally usually, it isn't as hard on my GI and has the benefits of long duration, rapid onset, pretty sure the bioavailability is a bit higher too.
 
hmmm....thanks. Did the rectal thing and it was indeed MUCH better, in other ways as well as getting rid of the stomach problem. Just a shame it's not the sort of thing you can do while you're out and about! Gonna stick to that wherever possible from now on I think though.
 
A lot of this is to do with cutting agents and stuff, but amphetamine in itself is very caustic, and long-term use is likely to result in damage to the stomach lining. In fact, it could be argued that in the interest of harm reduction - assuming your material is pure, your hygiene immaculate, and your dosages reasonable, taking considerable doses (even therapeutic) of amphetamines daily - it is more safe to administer intravenously. An ADD patient I know was told this by two specialist doctors, and it makes sense. Pure amphetamine is not good for your stomach lining. With irregular use, it's probably just a bit of acid reflux or your stomach disagreeing with cutting agents.
 
Psychonauticunt said:
A lot of this is to do with cutting agents and stuff, but amphetamine in itself is very caustic, and long-term use is likely to result in damage to the stomach lining. In fact, it could be argued that in the interest of harm reduction - assuming your material is pure, your hygiene immaculate, and your dosages reasonable, taking considerable doses (even therapeutic) of amphetamines daily - it is more safe to administer intravenously. An ADD patient I know was told this by two specialist doctors, and it makes sense. Pure amphetamine is not good for your stomach lining. With irregular use, it's probably just a bit of acid reflux or your stomach disagreeing with cutting agents.
Click to expand...

it is so not right to be promoting IV use.....
 
Not only is that information against OD guidelines, but it certainly can't be argued in interest of harm reduction that IV is the safest way to administer drugs, just if your drugs are pure. This is not true, and wonder how you think IV use is safer than say, oral administration.

I'm prescribed pharmaceutical grade methamphetamine, it's best and safest taken orally, and to suggest otherwise, that IV is somehow safer as long as your drugs are pure, is not true, nor is it HR.

If it's caustic to the stomach lining, which is designed to endure extremely acidic conditions, then there is no way you can say it's safer to administer it intravenously, directly into your cardiovascular system.
 
Psychonauticunt said:
A lot of this is to do with cutting agents and stuff, but amphetamine in itself is very caustic, and long-term use is likely to result in damage to the stomach lining. In fact, it could be argued that in the interest of harm reduction - assuming your material is pure, your hygiene immaculate, and your dosages reasonable, taking considerable doses (even therapeutic) of amphetamines daily - it is more safe to administer intravenously. An ADD patient I know was told this by two specialist doctors, and it makes sense. Pure amphetamine is not good for your stomach lining. With irregular use, it's probably just a bit of acid reflux or your stomach disagreeing with cutting agents.
Click to expand...

Yea because damaging your veins is so much better..........
....
 
Not to mention your heart. 100% Bioavailability does not make the best/safest ROA.
 
oral amphetamines are the best/safest/most efficient ROA, unless you're OK with plugging, but if it's street stuff, i wouldn't plug it, cause i've seen some odd fillers in street drugs (crushed up glass [actual glass, not meth] among other things) that i would not want up my ass.
 
^Which is why you should acetone wash any street drugs that may present themselves before you.
 
Plugging troubleshooting please?

Rather than start yet another plugging thread, I'm going to revive this one...

So, about plugging amphetamines (sulphate powder). Read up about it, done all that's recommended (clear bowels, dissolve in about 3ml water, use oral syringe, lie on side for a while etc.). As I mentioned before, it works pretty well (and avoids the nasty stomach issue). However, it certainly doesn't work as well as I'd been hoping. I'd say I get about 50% of the effects that I would from the same oral dose.

From what I have read, the bioavailability should be greater if anything. (Someone above says not though. Is this true? Why would this be? Intranasally works just fine, and a mucal membrane is a mucal membrane....) What could be the problem otherwise? Do I just happen to have an especially non-absorbent ass?!

Any troubleshooting help much appreciated.

PS - my supply is very trustworthy, certainly not cut with anything like glass (wouldn't imagine that dealer would stay in business/good health very long!)
 
Stomach ph is affected by amphetamine(s), and it can cause a quite nasty heartburn and increase in gastric acid. An effective supplement for this is betaine hydrochloride with pepsin.
 
bampot said:
PS - One thing that might be complicating this is that I also take a daily omeprazole (prilosec...a proton pump inhibitor) for gastric reflux....
Click to expand...

IMO omeprazole once a day wouldn't complicate the symptoms.
I've been taking 20mg omeprazole in the morning for the last 7 days and it has worked wonders for me, But I am not on any amphetamines presently. I think your GI problems would be worse if you weren't taking omeprazole. But this is just my opinion.
 
most problems with rectal administration come from not using the restroom first, so when you administer your solution, it gets absorbed into your feces and not into the walls of your rectum.

Or a mistake with your prep process. What are you using to plug? 1mL oral syringe?
 
bampot said:
So I've been taking speed a few days a week for a few months now...that is, amphetamine sulphate powder (not meth, not clinical, seems to be an exclusively European thing). Decent stuff, but still "street speed", so certainly impure to some extent. I don't binge or anything - I eat/sleep/exercise exactly as normal, just use it to feel a bit buzzed and energised. Probably comparable to 60mg or so of adderall daily.

Anyway, I've noticed that after, say, the third day of using it I start to get an extremely unpleasant feeling in my upper abdomen. Not acidic or cramping, just a nasty constant bloated aching feeling. This will still be lingering the next day, but after a day or two off it always goes away.

I'm wondering what this is caused by. Is it likely to be a direct result of the stuff irritating my stomach lining? Or over-basification of the stomach? Or is it more likely to be a pharmacological effect (I've heard for example that amphetamines can reduce blood flow to the stomach)? Then again perhaps it is due to something the product is cut with?

I intend to investigate this soon by trying the rectal route (insufflating wouldn't really tell me anything due to the drip)...that would at least tell me if it was a pharmacological problem or not. Just interested though - has anyone else experienced this? I'm assuming it doesn't commonly occur with clinical dexedrine or racemic mixtures, or else they wouldn't so widely prescribed. Then again, perhaps with some people it does happen, and it is just my personal digestive system that reacts badly?

Does anyone else regularly swallow street amphetamine sulphate, and if so, do you ever have stomach problems? Does anyone ever have any problems from taking adderall or dexedrine?

Bit of a vague rambling question - basically any enlightenment on possible causes of gastric reactions from amphetamines (or cutting agents) will much appreciated.

PS - One thing that might be complicating this is that I also take a daily omeprazole (prilosec...a proton pump inhibitor) for gastric reflux....
Click to expand...
I've been a frequent user of amphetamines. I began indulging for about 6 weeks. 8 days ago I began having abdominal pain. Today the pain and discomfort are very prevalent. I've quit the street product and began using prescription Folcolin with the same results. Am I just supposed to stop my daily routine or wait for this crap to disappear?
 
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