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Stimulating qualities of phenethylamines

Blueboxes

Greenlighter
Joined
Apr 17, 2012
Messages
12
I am curious about the stimulant properties of different psychedelic phenethylamines... The ones in question, are mescaline, 2CP, DOX, and MDMA. I would like to know how stimulating each one is, which is the least/ most physically stimulating, and how they compare to common stims like caffeine. As this is all about harm reduction, I would simply like as much information from first hand observation as possible from other members. Also, is LSD physically stimulating as well? I was under the belief that it wasn't as it is a tryptamine, but have read that a lot of people feel otherwise. Just to note, I am mostly concerned with physical stimulation and the effects on the body, and level of stress on the heart.
Thanks for any information in advance!
 
Hello and welcome to Bluelight's PD!

First of all: caffeine is IMO a nasty little bugger that does the trick helping with some work productivity and wakefulness but is otherwise a low-threshold acting stimulant that is not even that useful for attention or real energy. It's also quite jittery, it has lots of peripheral effects (which are sort of like side-effects or at least not the primarily targeted central effects.

The psychedelics you mention:
  • mescaline: I didn't find it to be that stimulating at all, it felt natural for me on the body but I did feel compelled to go through a deep and meaningful experience that in itself kept me going on for hours. But it wasn't like any push at all. Very little peripheral effects.
  • 2C-P: I have no experience with it. It's not essentially a stimulant but I do think there are peripheral side-effects. From what I read it does keep you going for hours but much much more pushy than something like mescaline. Expect it to be less natural feeling.
  • DOB: It's a psychedelic amphetamine and as such has pretty stimulating effects, for about 20 hours after dosing you can expect to be wide awake and pushed to engage in active things. The trip itself to me is also very compelling to get involved in deep and hard thinking for hours on end, so it's both pushing to the mind as well as the body. There are significant peripheral effects and you can expect to be exhausted afterwards. Also the dose can be tricky and it can be fucked up if you dose too high.
  • MDMA: This is a very common stimulant and empathogen, not so much a psychedelic. It has a very strong push and can feel unnatural but at the same time the effects on emotional opening can be very healing and pleasant. It is so much a stimulant that it depletes neurotransmitters in your brain, this can cause a hangover though if you keep the dose reasonable then the first time to try it, you will likely have few nasty after effects. But this varies between people. There is marked peripheral effects but considering the intense central stimulant effects it's quite alright IMO.
  • LSD: It is indeed stimulating but mostly like I described mescaline. It feels very natural and flowing but it does keep you up and going. Stimulation yes, but peripheral, quite limited though this is dependent on dose, redosing and how long you stay awake.
 
It may be worthwhile to mention the nbome series here as well. I've only got experience with 25I, but find it to be quite stimulating. I often have to take something to put myself to sleep after an experience, though this is probably my fault for engaging in such experiences almost exclusively at night. Would be interested to see how this compound behaves during the day. Regardless, as mentioned above, the DOX series are amphetamines, so that could expected. Beyond that, I think the stimulation value of PEAs is going to be highly dependent on the individual compound, and will vary widely from compound to compound. For instance, I've heard 2C-I to be stimulating, but found 2C-E to be quite something of a somnolent, or at the very least non-stimulating, experience.

Also, first post!
 
Hi solipsis, Thanks for the information! Based on your experience, would you say that Mescaline or LSD are stimulating enough to cause any significant stress on the heart? Also in the case that they do increase heart rate or put stress on the heart, would either be as much as caffeine or nicotine? I have found amphetamine to be uncomfortable in the stimulating sense and am curious as to whether Mescaline would bring about similar issues.

----

Do you have any experience with mescaline meateor? Ive heard 2C-I to be stimulating as well so I figured I would stay away from that one lol. So just because something is a phenethylamine doesn't mean that it is guaranteed to be physically stimulating? I just thought it was a characteristic of the class..
 
Last edited by a moderator:
Merged your posts, blueboxes.

Mescaline and LSD can both raise blood pressure and blood rate - as do virtually all phenethylamines - but significantly? Well I think that is dependent mostly on if you are freaking our or not. If you are calm throughout the trip it should be okay but if you are having a difficult and stressful time it can give things like palpitations. But seriously hard stress, meh. Such palpitations I mention would be psychosomatic and nothing to really worry about IMO. These two drugs are quite quite benign. Mescaline feels most benign but in reality LSD is probably most benign.

Important question: do you suffer from heart disease or are you just worried??

Just because something is a phenethylamine doesn't guarantee it to feel stimulating, but that doesn't necessarily need to be reflected on the effect on your heart and other vital organs.
DOB is definitely one to stay away from if you are even only worried about stress on the heart and blood vessels.
2C-I is not too good either, 2C-P can also be a tough one, 2C-E is so-so. I don't think I agree about the somnolence (causing sleep), no. It does give me a body load that makes me wanna lie down lethargically but I have no illusions that it doesn't affect heartrate and BP.

Amphetamine can indeed be uncomfortable, but it's pretty important to mention the dosage you took. If it was at normal therapeutic doses then it's more tricky, while at high recreational doses it's quite natural to feel an uncomfortable stimulation.

If you are not okay with amphetamine then you probably might want to avoid MDMA as well.
 
Well, the last time I used amphetamines, it was 30 mg of dextro-amphetamine that sent me into a panic attack and I got paranoid about my heart.. So I went to the walk in, they checked me out gave me a script to xanax and sent me on my way.. About a week before that though, I had a rough time with some MDMA and alcohol, and my girl freaked out because I was too messed up and made me go to the hospital.. She said my lips were blue and face was white, but idk, she was on them too and they were trippy... regardless, I was released the same night and have had multiple ECG's since then by my own request and have read clean everytime, but I just worry a little bit about heart health these days as I get palpitations occasionally..

I do use mushrooms occasionally though and have had no issues as well as having used LSD a few times since then. If mescaline is no worse on the heart than LSD than I have nothing to worry about because my body handles that just fine.. I learned my lesson back then though, and always research everything before taking it these days lol hence why I am here. I have never had any indication of heart issues other than palpitations my doctor does not seem worried about, however I would rather be over safe than sorry.
 
That's very wise.

Well I've only done mescaline once and it was synthetic product but like I said it felt harmless to me and I haven't heard about complications with it with normal use. Stimulants are what you should avoid most at least that is what it sounds like, and too right because IMO they are often shitty by nature.
2C's can vary to begin with but they are typically more mescaline-like than amphetamine-like. Something like 2C-C or 2C-B should be fine to experiment with but others like 2C-I, 2C-D, 2C-E, 2C-P and 2C-T-7 you should probably be much more careful with and build up your trial dose even more slowly than with other 2C's.

I don't know what you are looking for but 4-HO tryptamines might be more your thing. I find those to be physically easy and psychologically very interesting and beautiful.

Again: avoid DOx compounds, they can be interesting if you have little trouble with stimulants but otherwise they can be troublesome or even hellish. That inclused Bromo-dragonfly. With your constitution I think you'd better avoid that like the plague and consider that with every new batch of blotters you get.

Eh I think that about covers my advice on several sorts of drugs that interest you.
 
Thanks I really appreciate all the info! And I do certainly enjoy most tryptamines I have tried and definitely look forward to getting my hands on some more if I could only find some.. The last time I tried online I was ripped off so I am a little sketch about trying again :( maybe someday soon I will though as there are a few I really want to try!
 
Something like 2C-C or 2C-B should be fine to experiment with...

Im not sure about this one...I have taken a good amount of 2c-b and while I have never experienced it to be overwhelmingly amphetamine-like...it is pretty stimulating, at times I could compare it to MDMA in that regard although I may be confusing some euphoria with physical stimulation. Nevertheless It will raise your heart rate noticeably, I know that much. It seems as though you are worried because you have a heart condition or anxiety issues of some sort, so my advice is to be very careful if your gonna mess with substances that have such an impact on your body. None of these substances are extremely well researched either, so you may be better sticking with the old psychs like LSD and Mescaline...both are tried and true, and dont tend to kill people.
 
That's why I said about other 2C-X to build up the dose even more slowly than with other PEAs. So that doesn't mean diving right in with 2C-C or 2C-B. Yes it can be stimulating but IMO it starts to get 'serious' only at quite high doses and not threatening right from the get go, in that respect I found them the mildest of the 2C's (2C-C being the absolute mildest I have tried yet, not sure about T-21 which I still have to try) making it approaching mescaline which is of course a direct relative.
2C-D is rather what I would call of low potency, but when the effects become apparent so does a stimmy edge. Okay for most but perhaps not if you're not up for edges.
 
I am interested in trying some of the 2C's someday, but I want my first psychedelic phenethylamine to be Mescaline :) as long as everyone agrees that it is pretty mild physically and not very stimulating then I will be trying it soon. Anyone have any favorite tryptamines that are still available?
 
About everyone agreeing, guess again:
http://www.bluelight.ru/vb/threads/372602-How-stimulating-is-2ce-Mescaline

So it can certainly vary how stimulating it is but most people find it tolerable and/or pleasurable. Not all users though, one got a seriously elevated heartrate. Still doesn't mean it'd feel like dirty shit in your body like a lot of actual stimulants.

But you either have to accept some stimulation or rule out most on the category. Even though tryptamines tend to make people more lethargic and the 4-HO's are quite easy on the body they still boost body and mind activity in ways and in the end are pretty much all stimulating. And panic attacks are also still always a possibility.

It's just that when you compare very comfy psychedelics with stimulants, I think it's a risk worth considering unless you are
really diagnosed with a disease that makes your heart like that bus in the movie Speed.

About tryptamines, please research them yourself. I'd choose 4-HO's over 4-AcO's at least at the start. 4-HO-MET and 4-HO-MiPT are interesting, 4-AcO-DMT is also beautiful though. Probably best to stay away from 5-MeO tryptamines, they can be uncomfortably loaded with stimulating energy.
 
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