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Stimulants increase CV endurance?

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sj227

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Jun 19, 2009
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ok heres one for you med students.

i know cardiovascualr endurance is basically how strong your heart is. So as the heart is a muscle exercising helps to condition or strengthen it.

my question: if one takes stimulants of some kind and this elevates the heart rate to say 120 - 140bpm (not excessive just like a mild workout) is this the same as actually doing a mild workout with relation to the cv endurance side of things?
 
I could be wrong but I am pretty sure that non thearpeutic use of amphetamines and cocaine is pretty bad for the heart. With these drugs your heart rate is just raised for a short time like when you exercise, its raised for hours, sometimes most of the day. I imagine this places alot of pressure on your heart. Also combined with physcial exertion like dancing for hours it would be worse.

I'm pretty sure in the US that cocaine is a huge cause of presentation into emergency rooms because of heart papiltations or heart attack.

methamphetamine, mephedrone, MDPV, have kept my heart raised for an entire day. mephedrone is reportedly really bad for your heart and your circulatory system.

Someone with more knowledge than me might want to comment.
 
I haven't started bio-chem really yet, but from what I understand... no. When you are doing exercises that increase your cardiovascular strength, you are increasing the strength of the heart muscle. Taking stimulants is raising your heart rate via the release of norepinephrine and dopamine, so you are getting the increased beats-per-minute but your body is not going through the process of creating new muscle.

I could be wrong on that as I have so far studied mainly pharmacology, not bio-chemistry though I have the text book I need to get started on.

Also, the vasoconstriction that stimulants cause would also put extra strain on your heart and like mentioned above for an extended period compared to exercise.
 
I also haven't looked this up, but I can say with near certainty that amphetamines do not improve cardiovascular endurance. I believe the main cause of ED presentation from cocaine that psytaco mentioned is related to the vasoconstriction (-> decreased oxygen/nutrient supply to muscles and accumulation of toxic metabolites).
 
sj227 said:
ok heres one for you med students.

i know cardiovascualr endurance is basically how strong your heart is. So as the heart is a muscle exercising helps to condition or strengthen it.

my question: if one takes stimulants of some kind and this elevates the heart rate to say 120 - 140bpm (not excessive just like a mild workout) is this the same as actually doing a mild workout with relation to the cv endurance side of things?
Click to expand...

I think it's bad for you, but not sure. With amphetamine type drugs in the system, 1 is capable of cardiovascular endurance that they wouldn't otherwise be capable of. With duromine combined with an SSRI that multiplied the effects of duromine I was able to ride 60kms every afternoon with a sustained heart rate of 140bpm with little effort even though I had become a lazy 90kg fatty.

After a couple of weeks of this I probably built up the heart muscle to an extend I was naturally fit. I stopped the duromine after 2 weeks as it was effecting me too strongly, and I found that my physical endurance was no longer as good, in that I didn't/couldn't be bothered riding the distances I did every afternoon. Maybe it was more the motivational side of the drug that stopped me continuiing the same routine after I stopped it.
 
The heart will actually grow larger if you use stimulants daily, long term. This allows for greater cardiac output however as you'll see if you ever study exercise physiology, the heart is only 1 part of many physiological changes which occur when a person gets 'fit'. One of the major changes which will be missed out on is the changes to the energy mechanisms of the body (metabolism), specifically the phosphocreatine, glucolysis and citric acid cycles.

I don't know if that helped much, but that is as much as I can tell you from what I have learnt in my degree so far.
 
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