Still don't know, can you have GBL and GHB in same night...

[rollergirl76]

OKAY, let me try this AGAIN. I posted this question last night but the topic was closed, I was told to do a "search" here. Well I did, and I still do not know the answer, possibly because my connection is damn slow and searching takes forever.
...so if anyone has real info on my question, please reply, it's like a "yes/no" answer. I have been given great info from this board before, so please help me out here.
Here is my question again:
Say you have GHB and GBL. You take the GHB when you are rolling, but the like GBL when you are coming down from the roll, closer to bedtime. Other than obvious problem of overdosing, say you are very careful with doses, and experienced with both GHB and GBL and know their sources, etc... is it bad to have them both in your system at the same time? i.e. IS IT BAD TO TAKE GBL AND GHB IN THE SAME NIGHT?

 

[NoriegA]

Yes, go ahead have fun...

 

[quale]

GBL is biotransfored into GHB, or at least are both transfored to the same active constituent. I believe this transformation is pretty damn efficet (equal moles of GHB give equal effect to equal moles GBL...though myabe the GBL takes a longer coming on).
In either case just to be safe treat it like you were doing two things of GHB, you shouldn't run into any danger there.
BTW probably the topic was closed b/c it belongs in health Q&A
BTW what was the poing of GHB at all...just to have a powder form (I mean I am all about that..I hate liquids but was there any other reason it was popular not GBL?)
[ 13 June 2002: Message edited by: quale ]

 

[Fujicrow]

GBL takes less time to hit than NaGHB or KGHB.

 

[badjessejames]

Sorry fulicrow.....there is no way that GBL comes on faster than GHB.GBL converts to GHB using your liver...which is why noone knows if long term GBL use is completly safe. Also I feel GHB has a much cleaner buzz....GBL makes me and others I know dizzy and sick, it comes on slower, lasts longer and is not proven safe as of yet. Do the conversion people...it's easy.

 

[Drug Dustbin]

GBL is rapidly and irreversibly hydrolysed into GHB by peripheral gamma-lactonase, not by stomach acid (at least in significant quantities). GBL is more rapidly absorbed and has greater bioavailability than GHB on an equimolar basis. In spite of the rapid hydrolysis of the lactone in blood, the distributive pattern of GBL may be different from that of GHB. This can be one reason why GBL gives more prolonged hypnotic effects than GHB.
References:
Lettieri J, Fung H-L "Improved pharmacological activity via
pro-drug modification: comparative pharmacokinetics of sodium
gamma-hydroxybutyrate and gamma-butyrolactone"
Research Communications in Chemical Pathology and Pharmacology
1978, 22(1)107-118
Bernasconi R, Mathivet P, Bischoff S, Marescaux C
"Gamma-hydroxybutyric acid: an endogenous neuromodulator with
abuse potential?" Trends in Pharmacological Sciences 1999 vol.20, 135-141
[ 13 June 2002: Message edited by: Drug Dustbin ]

 

[rollergirl76]

THANKS!!! I got the info I needed.
Also, just my 2 cents, GBL hits me waaaaayy faster and harder than GHB. I feel it in 5-10 minutes. Takes me 20-30 for GHB. GHB makes me want to dance and hug and talk a lot, GBL turns me into a porn star and then makes me sleepy! (Always used w/ E.) I just wanted to know if it was very bad to have both in the same night of partying.
Thanks for the info.

 

[PhreeX]

Originally posted by rollergirl76:
THANKS!!! I got the info I needed.GREAT!!!! Now I can close this thread, AGAIN, YET ANOTHER TIME, ONCE MORE, EVEN THOUGH I ALREADY DID!
I knoe searching takes awhile, but if you had typed in "GHB" or "GBL" in the search field, selected "Other Drugs" for the forum, then WAITED UNTIL IT FINISHED (it can take a few minutes) you could have found your answer....