Stable dermorphin solution/solvent at room temp?

[jahh]

Would you be so kind and elaborate on the mentioned routes of application, please?
I'd like to read some details, in particular how the sublingual dosage was prepared and what time interval expended between application and feeling the first effects.

Thanks!

- Murphy

That would be very interesting!
Also, at the dosage for total pain relief, were you able to function normally?( or did you feel tired, dizzy, like vomiting etc....)

thanks

 

[jahh]

The last 3 guys who tried this peptide had nothing but positive things to say about it
But haven't seen any more posts from them since8)
Hope nothing serious has happened to them.

 

[hamhurricane]

please do not assume this is a safe medication just because I have tried it. I could have already caused injury that has yet to show up; this is strictly an experimental exotic compound with virtually no human data and limited animal research data.

Well, I think you're forgetting the hundreds (if not thousands) of years it has been used as a traditional medicine in the form of polymedusa bicolor skin secretions, not to mention the odd appearance in the urine of autistic children.

 

[MadWolfZX]

Okay, I am going to report my subjective personal opinion on this product from sublingual and subcutaneous injection.

Both applications had identical results.

I ended up using 500ug for both, and results were identical. I got most relief from pain, roughly equal to 100mg of hydrocodone. I experienced the standard opiate relaxation effect. However, I did not get 'euphoria' from the dermorphin, but I rarely get euphoria these days. I have used moderate levels of opiates for 3+ years daily for chronic pain. I don't recommend the doses listed above for any particular person, and especially not for new opiate users, those are simply the dose ranged ideal for ME. Using more, up to 1mg did not seem to make a perceivable difference. Duration was in the 4-6 hour range for both ROAs. I conclude the cost is too high to be practical.

My material I can assure you was pure and in tact and really was demorphin. I used a highly reputable bio-supply/synth lab that routinely supplies the materials used by reputable research facilities.

If one does want to get and use this material, I did find the method of using tiny capped sterilized vials containing a small amount of bacstereostatic water and the dermorphin crystals dissoved into these to be ideal. I stored them at -20C and removed a vial for each application. It thawed to liquid in a matter of minutes.

I can not report on IV use. It's not that I did not try, but I have terrible veins for IV use, even medical staff have a tough time on many occasions getting good access. I don't have damaged veins or anything, I do not and have not used IV injection on any kind of frequent basis. It's just hard as heck to see my veins and get a good stick; they are deep under my skin and difficult to locate, even the normal main ones; even my wrist; I can appear to directly contact a vein and not get access. I'll try again to IV, but so far the result has just been a bunch of annoying needle sticks. I'll add the conclusion of IV use if I accomplish that, or I may ask a retired nurse I know, but she would probably freak if I went to her and asked her to IV some experimental drug into me.

I know that placebo is a possibility. But I will note that I purposely let myself get into withdrawl and then used the dermorphin, and it had near total alleviation of symptoms.

 

[jahh]

Very interesting
I can see other users of this peptide having dramatic differences in there results, based on their source

Looks like you'll have to "suck it up" and see for yourself

Okay, I am going to report my subjective personal opinion on this product from sublingual and subcutaneous injection.

Both applications had identical results.

I ended up using 500ug for both, and results were identical. I got most relief from pain, roughly equal to 100mg of hydrocodone. I experienced the standard opiate relaxation effect. However, I did not get 'euphoria' from the dermorphin, but I rarely get euphoria these days. I have used moderate levels of opiates for 3+ years daily for chronic pain. I don't recommend the doses listed above for any particular person, and especially not for new opiate users, those are simply the dose ranged ideal for ME. Using more, up to 1mg did not seem to make a perceivable difference. Duration was in the 4-6 hour range for both ROAs. I conclude the cost is too high to be practical.

My material I can assure you was pure and in tact and really was demorphin. I used a highly reputable bio-supply/synth lab that routinely supplies the materials used by reputable research facilities.

If one does want to get and use this material, I did find the method of using tiny capped sterilized vials containing a small amount of bacstereostatic water and the dermorphin crystals dissoved into these to be ideal. I stored them at -20C and removed a vial for each application. It thawed to liquid in a matter of minutes.

I can not report on IV use. It's not that I did not try, but I have terrible veins for IV use, even medical staff have a tough time on many occasions getting good access. I don't have damaged veins or anything, I do not and have not used IV injection on any kind of frequent basis. It's just hard as heck to see my veins and get a good stick; they are deep under my skin and difficult to locate, even the normal main ones; even my wrist; I can appear to directly contact a vein and not get access. I'll try again to IV, but so far the result has just been a bunch of annoying needle sticks. I'll add the conclusion of IV use if I accomplish that, or I may ask a retired nurse I know, but she would probably freak if I went to her and asked her to IV some experimental drug into me.

I know that placebo is a possibility. But I will note that I purposely let myself get into withdrawl and then used the dermorphin, and it had near total alleviation of symptoms.

 

[jahh]

If this peptide is active by sublingual admin. , would it also be active by rectal admin.?

 

[jahh]

If this peptide is active by sublingual admin. , would it also be active by rectal admin.?

Anyone?

 

[MadWolfZX]

If this peptide is active by sublingual admin. , would it also be active by rectal admin.?

Anyone?

I did dissolve the material in a tiny volume of water (10 units of a 30unit 1ml syringe) and squirted this solution under my tongue and held it for 20 minutes or so. It was active via this ROA. I did dry my mouth with a cloth before hand in order to minimize risk of excess saliva diluting/carrying away the solution before it could absorb.

Chris

 

[daddysgone]

I am EXTREMELY skeptical about your reports that the duration is 4-6 hours.
I also have experience with this subtstance (you can read my reports about if you use the search function). First off, I found no positive effects from it whatsoever.

I understand that 1 person's subjective reports do not hold much weight, but from a strictly pharmacological point of view, I don't see how this substance could have such a long duration. The main problem with peptides is their extremely short duration. While I have no doubt that this substance could exert a typical opioid effect for 30 minutes or so, I just don't see how this peptide could be active for 4-6 hours.-DG

 

[MadWolfZX]

I am EXTREMELY skeptical about your reports that the duration is 4-6 hours.
I also have experience with this subtstance (you can read my reports about if you use the search function). First off, I found no positive effects from it whatsoever.

I understand that 1 person's subjective reports do not hold much weight, but from a strictly pharmacological point of view, I don't see how this substance could have such a long duration. The main problem with peptides is their extremely short duration. While I have no doubt that this substance could exert a typical opioid effect for 30 minutes or so, I just don't see how this peptide could be active for 4-6 hours.-DG

I'm skeptical of the quality of product you acquired based on your consistent negative experiences. I spent A LOT of money to ensure the product was exactly as represented and to buy supplies to ensure safe/proper administration/storage. In the end, I find it way to costly to use on a regular basis, but I'll spend a bit for experimentation once in a while, as I find it fun. I will never buy dermorphin again, though, as much cheaper options are just as or more effective. But I will try some more experimental drugs/chemicals in the future of course - for fun.

 

[jahh]

Maybe the dermorphin analog : (phe4)-dermorphin (1-4) amide would be a better choice, it seems to pass the BBB. There seems to be a number of analogs that seem more practical than the parent. I think some of the experiences with this peptide are so far different because of it's instability and maybe some used one of the analogs?

Would the dosage be the same for the analog?

 

[jahh]

Maybe the dermorphin analog : (phe4)-dermorphin (1-4) amide would be a better choice, it seems to pass the BBB. There seems to be a number of analogs that seem more practical than the parent. I think some of the experiences with this peptide are so far different because of it's instability and maybe some used one of the analogs?

Would the dosage be the same for the analog?

^ anyone?

 

[thesomoan]

I am EXTREMELY skeptical about your reports that the duration is 4-6 hours.
I also have experience with this subtstance (you can read my reports about if you use the search function). First off, I found no positive effects from it whatsoever.

I understand that 1 person's subjective reports do not hold much weight, but from a strictly pharmacological point of view, I don't see how this substance could have such a long duration. The main problem with peptides is their extremely short duration. While I have no doubt that this substance could exert a typical opioid effect for 30 minutes or so, I just don't see how this peptide could be active for 4-6 hours.-DG

Dermorphin is a peptide which cannot be coded for in higher mammals, our DNA does not code for all the nessacary amino acids (wikipedia), which means that Dermorphin likely has a much longer half life than other peptides as our body is much less equipped to metabolize it which makes a longer duration than other peptides feasible.

 

[RhythmSpring]

I imagine the issue would be less quality of product and more quality of keeping the product stable and ROA, no?

It seems quite hard to keep this substance stable and get into the system gracefully.