st john's wort, how many days before mdma should I stop

[barrypepper]

Planning on a big night next week, only issue is that I've been over-using serotonergic drugs recently, well MDMA and mainly mephedrone. Not over-using them lots, just a little. I had a big night on MDMA about a month ago, and in the last 2 weeks I've used about 2grams of mephedrone.

I don't want my 5ht receptors to have down-regulated to such an extent that I won't enjoy next week. So I've been taking st johns wort in moderate doses for the last few days. But my understanding of it, is that it almost acts as an SSRI, therefore re-sensitising the receptors. However I also know that taking it at the same time, or too close to the time of using MDMA will prevent the receptors from giving you the MDMA effects your after.

So my question is, how long before I plan on taking MDMA should I stop the St Johns Wort?

Also, should I take some 5htp the day before, and the day of the MDMA to boost available serotonin?

 

[StoneHappyMonday]

St Johns Wort has been placed in scientific tests as no better than placebo. It won't affect your MDMA at all. 5HTP is also a waste of time and money.

How about you just take MDMA and quit worrying.

 

[barrypepper]

St Johns Wort has been placed in scientific tests as no better than placebo. It won't affect your MDMA at all. 5HTP is also a waste of time and money.

How about you just take MDMA and quit worrying.

Really, on both counts?

I've read scientific evidence that states the contrary.

And, as long as you take it correctly, 5htp sounds like it will boost serotonin levels.