JohnBoy2000
Bluelighter
- Joined
- May 11, 2016
- Messages
- 2,650
SSRI's - namely Sertraline and Venlafaxine - are licensed for social anxiety.
I think others are scripted for that purpose also.
But mirtazapine is not.
And in my experience - Mirtazapine does nothing to improve sociability, mood wise; it might improve general cognizance and functionality - but does not put one in the mood for socializing; at least - it didn't for me - at all.
SSRI's and venlafaxine are like magic for this.
Yet they both increase synaptic serotonin - albeit by different means.
Is this attributable to cross over of intra-neuronal post synaptic transduction cascades - ultimately mirtazapine negates its own social benefits; something like that?
Perhaps alpha 2 adrenergic blockade also releases transmitters which give rise to that cross-over cancellation - where as SSRI's - focusing exclusively on the 5HT transporter, don't have this effect?
Is there any other explanation as to why SSRI's work for sociability - and Mirtazapine does not?
I think others are scripted for that purpose also.
But mirtazapine is not.
And in my experience - Mirtazapine does nothing to improve sociability, mood wise; it might improve general cognizance and functionality - but does not put one in the mood for socializing; at least - it didn't for me - at all.
SSRI's and venlafaxine are like magic for this.
Yet they both increase synaptic serotonin - albeit by different means.
Is this attributable to cross over of intra-neuronal post synaptic transduction cascades - ultimately mirtazapine negates its own social benefits; something like that?
Perhaps alpha 2 adrenergic blockade also releases transmitters which give rise to that cross-over cancellation - where as SSRI's - focusing exclusively on the 5HT transporter, don't have this effect?
Is there any other explanation as to why SSRI's work for sociability - and Mirtazapine does not?
