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Opioids SR-17018 for Opioid Reset

AddictivePersonality

AddictivePersonality

Greenlighter
Joined
Jul 28, 2026
Messages
11
Hi All,

So I will have some SR-17018 in hand tomorrow and have some questions.
If taking it to reset tolerance is stopping all other opiates the only way? Or does just the action of taking it help restore tolerance? Can it lower tolerance even when taken along with another opiate? The reason I ask is because I’m on 120mg Methadone and have to take an observed split dose of 60mg every other day except weekends but want to be able to lower my tolerance as much as possible because I no longer get any therapeutic benefit anymore which has taken a toll on my mental and physical wellbeing. Any insight will be highly appreciated thanks :))
 
so many people are jumping on this and it
kinda doesn’t make sense… bl is promoting a Johns Hopkins study as well.. please consider participating.. well does it actually work?

Tronica

Recruiting Thread 'Seeking US adults with experience using SR-17018 for anonymous Johns Hopkins online survey study'

I am Austin Zamarripa, Ph.D., an Assistant Professor at Johns Hopkins University School of Medicine, and we are conducting a research study seeking adult volunteers in the US to complete an online survey about SR-17018 use. We want to learn more about experiences individuals feel when using SR-17018.

This study has received ethical clearance from the Johns Hopkins Medicine IRB with the assigned protocol number: IRB00557700. Study recruitment is currently open beginning June 2026. The study is expected to remain open until approximately October 2026, or until recruitment is complete.

If...
  • Like
 
neversickanymore said:
so many people are jumping on this and it
kinda doesn’t make sense… bl is promoting a Johns Hopkins study as well.. please consider participating.. well does it actually work?

Tronica

Recruiting Thread 'Seeking US adults with experience using SR-17018 for anonymous Johns Hopkins online survey study'

I am Austin Zamarripa, Ph.D., an Assistant Professor at Johns Hopkins University School of Medicine, and we are conducting a research study seeking adult volunteers in the US to complete an online survey about SR-17018 use. We want to learn more about experiences individuals feel when using SR-17018.

This study has received ethical clearance from the Johns Hopkins Medicine IRB with the assigned protocol number: IRB00557700. Study recruitment is currently open beginning June 2026. The study is expected to remain open until approximately October 2026, or until recruitment is complete.

If...
  • Like
Click to expand...
No compensation, no participation…
 
why care if you get compensated? To be honest why would i care:. i dont so why in tf should u care?? i don’t but i have done this all for “free” yeah you have all the time in the world to educate me.. that’s all the time in the world.. tick tock.. but you have forever.. why am i caring about u?


you know what i care about is amazing people.. people struggling with drug addiction and super bright researchers like Tron.
 
Last edited:
AddictivePersonality said:
Hi All,

So I will have some SR-17018 in hand tomorrow and have some questions.
If taking it to reset tolerance is stopping all other opiates the only way? Or does just the action of taking it help restore tolerance? Can it lower tolerance even when taken along with another opiate? The reason I ask is because I’m on 120mg Methadone and have to take an observed split dose of 60mg every other day except weekends but want to be able to lower my tolerance as much as possible because I no longer get any therapeutic benefit anymore which has taken a toll on my mental and physical wellbeing. Any insight will be highly appreciated thanks :))
Click to expand...
How did your experience with it go?
 
TheplugsPLUG said:
How did your experience with it go?
Click to expand...
It’s been going well👍🏽 a little hard with having to dose Methadone 60mg one half of my split 120mg MTD dose every Mon, Wed, Fri. I’d like to go without dosing for longer than two consecutive days “Saturday, Sunday” I’m also trying to skip dosing “Tuesday, Thursday” since I can .. but even after just the two days I feel it lowered/reversed my tolerance exceptionally well!
 
Last edited:
AddictivePersonality said:
It’s been going well👍🏽 a little hard with having to dose Methadone 60mg one half of my split 120mg MTD dose every Mon, Wed, Fri. I’d like to go without dosing for longer than two consecutive days “Saturday, Sunday” I’m also trying to skip dosing “Tuesday, Thursday” since I can .. but even after just the two days I feel it lowered/reversed my tolerance exceptionally well!
Click to expand...
Yea this stuff has worked amazing for me. I barely had any type of withdrawals getting off fetty.
 
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