TreeTrippingToker seems to not know what he speaks of... ok, as a superStar DJ know world wide for my masterfull smooth as silk beat-matching abilities*, here is my run-down:
MDA - As far as I am concerned, it's a little to trippy - you may hear things that are not there...
MDMA - WONDERFULL (once you get use to it) .. it seems the music is just apart of you, and you dominate the tables with ease... but as I hinted to, it takes some getting used to so as not to be 'over agressive' .. but some of my best sets, hell, all of my best sets were while I was blowing the fuck up...
LSD - IMO, avoid this one.. you will hear things that are not there and you THINK you're doing better then you really are.. some of the sets I recorded while on LSD were laughable -nothing but trainwrecks... but when I was spinning I thought it was the best set of my life... still, if you get used to it, you might have great success... YMMV..
PCP - Wouldn't know, never had a good PCP experience alone, I think spinning would be VERY difficult due to the EXTREME impaired senses...
THC - Again, wouldn't know... I imagine you would be slower then usual, probably pretty sloppy, and would no doubt throw in many "bong hit" samples.... I would avoid this..
Coke - You would probably be flying through the vinyl, until you had to do another line every 15 minutes... still, it might improve you abilities...
Crack - Hardly possible, when you take a hit of crack the rush lasts for like a minute, then you want more... so unless you had someone loading a pipe for you, this wouldn't be possible... you would also be too edgy and would probably fuck up a lot of mixes...
Crstal Meth - If anything, this would be the best... you're speeded up and more focused then ever .. if I had my choice of drugs for spinning (and I wasn't a narcotics junkie) it would be meth ...
NOS - Yeah right... if you could even stand up you wouldn't have a chance in hell of being able to lift the needle, let alone beat match... NOS is for AFTER your sets done..
Perscriton Pills and Painkillers - Well, it depends on you... at this point in my life, I would spin my BEST on strong narcotics (Oxycodone, Morphine, Fentanyl, etc..) but thats because these things give me energy and magical powers - for most people, prescription PK's and downers would just make you spin like Keoki used to - horrible trainwrecks, falls off the tables, etc... if you're new to the world of prescription narcotics/downers I would NOT have my first experience behind the tables...
Hope this helps! Again, everyone is differn't .. one DJ I knew could do INCREDIBLE things while tripping his balls off, but if he had a little speed he just couldn't maintain....
Play around, see what works...
*I am not a world famous DJ, I spin in my bedroom, I tell girls I am a famous DJ to get laid, it has yet to work...