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Bupe Some of you may not care but some docs do care read my little story below if your board !!!!! šŸ˜ŽšŸ˜Ž

gymguy30

Bluelighter
Joined
Jun 29, 2025
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226
Just wanted to share my experience for anyone who might be in a similar spot.

A couple months ago, I finally opened up to my primary care doctor (he’s internal medicine) and told him I had been abusing opioids and spending over 1500 or more a month on them for several years and I couldn’t take it no more. Which to be honest he wouldn’t say it because he’s so shy but he was probably irritated considering the fact that he would prescribe tons of hydros anytime I wanted lol.

He told me he didn’t usually prescribe Suboxone or Subutex long-term, but he’d help in the short term while I found a clinic. He started me on 2mg/day of Suboxone films, which honestly did nothing for me. I was still using opiates like crazy — including 7-OH — even while on them. He also kept my Klonopin at 2mg/day, which I’d been prescribed for nearly 10 years.

Eventually, I used the Medicare Part D (my fav ) prescriber tool to look for a doctor who not only prescribed Subutex, but also other meds I might need — like Klonopin or possibly Xanax if I ever needed to be switched. I wanted someone who truly understood addiction and mental health, not someone who’d just see ā€œaddictā€ in my chart and dismiss me. I found this doctor, gave him a shot, and honestly — it was one of the best decisions I’ve made. He’s been solid from day one and treats me with actual respect.

At our first appointment, he looked over my chart and saw I had been prescribed 2mg/day of Klonopin. He then handed me a mental health questionnaire — stuff about my childhood, how I react to stress then and now, how badly certain things affect me emotionally, etc. After looking over it, he upped my Klonopin from 2mg to 3mg immediately, without me even asking. That alone was a huge help.

Right away, he said, ā€œOh no — tell your primary care I’m taking this over now.ā€ Then he said, ā€œWith your severe PTSD, generalized anxiety disorder, panic attacks, and depression, this is definitely an inadequate prescription for you. You need the Klonopin increased.ā€

That honestly shocked me. My old doctor had me convinced for years that 2mg/day was the maximum legal dose anyone could prescribe for Klonopin. I really believed that. Smh. I never thought it could be increased. But this new doc actually looked at my situation and symptoms — not just the number on a screen.

I also told him that the Suboxone films my primary gave me were making me nauseous. I’ll admit — that wasn’t completely true. They made me feel a little off, but mostly I just hated how they made me feel mentally. I knew Subutex worked better for me. So yeah, I might’ve stretched the truth a little to make that switch happen — just being honest.

He switched me from the 2mg Suboxone to 8mg of Subutex daily. After 5 or 6 days, I was still struggling hard with cravings. Real opioids and even 7-OH were still constantly on my mind. I called the office, and within 15 minutes he had a new script for 16mg waiting for me at my pharmacy. No hoops. No lectures. Just support. That kind of response meant a lot.

I did okay at 16mg, but then one night I had a super vivid dream about sniffing Roxy’s. I woke up literally about to relapse — ready to go call my guy and grab some OP40s or blues. I told my doctor straight up, and he upped me to 24mg of Subutex. Since then, I’ve been doing a lot better. I usually stick to 16mg/day, but I’ll take the full 24 if I’m having a really rough day. That extra tab is like a cushion when things get tough.

I also told him how thankful I was for the Klonopin increase, but lately my stress, anxiety, PTSD, and panic attacks had gotten worse. Most nights I’d be woken up by nightmares at like 2–3 a.m. and couldn’t fall back asleep. He didn’t blink. He said, ā€œAlright, I’m bumping you to 4mg/day. Try the extra at night and see how it helps. If it doesn’t do the trick, I’ll keep you at 4mg and we’ll add something like Ambien, Seroquel, or Temazepam.ā€ I haven’t tried those yet, but it’s nice knowing I’ve got options.

Also — and I know this isn’t ideal, so no judgment needed — but most of the time, my ROA for Subutex is intranasal. That’s just what works best for me in terms of managing cravings and feeling like it’s actually doing what it’s supposed to.

At the end of the day, this doctor actually treats me like a human being — not a junkie or a problem to manage. After years of being looked down on or brushed off, it’s been a huge relief to work with someone who listens, takes action quickly, and doesn’t make me feel like less of a person for my past. If you’re struggling and not getting real help, keep looking. There are good doctors out there who actually give a damn.
 
All things considered this is kinda crazy to me, as benzos and bupe together in high doses can kill, and those are some both decently high doses.
Im glad youre doing well, but I'm guessing 2mg kpin did it for you for a while, and eventually, you get a tolerance, so eventually, if you use these in the same manner as the 2mg, the 4s will end up working about the same as 2s before the bump up. But I hope it actually does help.
 
All things considered this is kinda crazy to me, as benzos and bupe together in high doses can kill, and those are some both decently high doses.
Im glad youre doing well, but I'm guessing 2mg kpin did it for you for a while, and eventually, you get a tolerance, so eventually, if you use these in the same manner as the 2mg, the 4s will end up working about the same as 2s before the bump up. But I hope it actually does help.
Well first off my man let me say i don't use 4mg kpins every day. Also you have no clue what I endured as a child furthermore you don't know what medications I need or in what doses. I'm not being rude brother. Let me state also that just because two substances are CNS depressants doesn’t mean the risks are all equal. There’s a huge pharmacological difference between combining Subutex (buprenorphine) and benzos vs combining full opioid agonists (like heroin, fentanyl, methadone) and benzos.

Let’s break it down based on real science — not fearmongering.


šŸ”¬ Key Differences That Reduce Risk


1. Ceiling Effect on Respiratory Depression (Partial Agonist)

  • Buprenorphine is a partial mu-opioid receptor agonist, meaning it plateaus in terms of respiratory depression at higher doses.
  • This ā€œceiling effectā€ dramatically reduces the risk of fatal respiratory depression.
  • In contrast, full agonists (like fentanyl or methadone) do not have a ceiling — the more you take, the more they suppress your breathing.

2. Receptor Affinity & Blocking Effect

  • Bupe binds very tightly to opioid receptors, often displacing or blocking full agonists.
  • This can actually act as a safety buffer, preventing other opioids from stacking on top and causing a fatal interaction.
  • When stabilized on Subutex, it’s actually harder to overdose on other opioids.


3. Stable Blood Levels in Maintenance Treatment

  • Subutex is typically taken daily, creating stable, consistent blood levels.
  • This is way safer than the binge-patterned use often seen with full agonists.
  • Overdose risk is highest when tolerance and levels fluctuate — which is far more common with illicit or non-prescribed opioid use.


🚨 Full Agonists + Benzos = One of the Deadliest Combos

  • When benzos (like Xanax or Klonopin) are combined with full opioids, the two potentiate each other.
  • That leads to a multiplicative effect on respiratory depression — not just additive.
  • Most opioid/benzo overdose deaths come from illicit full agonist use, not prescribed bupe + benzo combos.

Also I wanted to post some real life evidence that shows what you're saying is a little outdated my brother.

šŸ“Š Real-World Data Backs This


  • A 2018 study published in Drug and Alcohol Dependence found that bupe + benzos had significantly lower overdose mortality than methadone or heroin + benzos.
  • The FDA even updated its guidance in 2017, STATING:

ā€œThe benefit of continuing buprenorphine alongside benzodiazepines outweighs the risk — especially since discontinuing of buprenorphine increases the risk of relapse and overdose.ā€

āœ… Final Summary


Combining CNS depressants isn’t something to take lightly — but when it comes to bupe vs full agonists, the difference is night and day.

  • Buprenorphine’s ceiling effect, tight receptor binding, and stable blood levels make it far safer when taken with benzos than full opioids.
  • Full agonist opioids + benzos = one of the most lethal combinations in overdose statistics.
  • Bupe + benzos (when prescribed and monitored) is objectively less risky and clinically supported.

Let’s stop pretending they’re the same thing. They’re not.
 
Did you really just drop an ai summary my man?
Also I never said that its the 'same thing', nor did i say i know what you went through. I said that combo kills, which it does, and tried to explain why increasing dosages long term fucks with your body's equilibrium, which it does. Just trying to help.
 
Did you really just drop an ai summary my man?
Also I never said that its the 'same thing', nor did i say i know what you went through. I said that combo kills, which it does, and tried to explain why increasing dosages long term fucks with your body's equilibrium, which it does. Just trying to help.
Thank you brother for the help but my doctor has been in the field a very long time and it's ok thank you
 
*You’re
*Bored


Didn’t help but best of luck/sorry that happened/happy for you either way
 
I don’t have an issue with the guy and it’s an inside joke


Sleep it off. I’ll get you the number to that therapist we talked about. Your wife and I been discussing your…condition in between Spanish lessons and we both think it’s best for you to turn your life around. All that anger isn’t healthy and is stressing y’all as I’m sure you’re aware. She wants better, not bitter, bro-bro


Anyway, reported for spam/offtopic. Ban evasion, etc
Wtf is going on ?? Just saw this
 
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