So im switching to methadone

[caseface99]

So i leveled with my doctor recently who had me on suboxone after catching me abusing my oxy. I told them that i certainly wasnt going to quit drugs irregardless of what they say and do. i complained that i wont be able to use opiates while on suboxone and so in response they said i should switch to methadone because ill be able to get high on fentanyl and heroin and drugs like that while on methadone. started at 60mg. what dose will get me feeling gooder? im on a court order for prescriptions is why i was taking the suboxone.

 

[neversickanymore]

If you want to keep rolling case I would consider a couple of things. I would certainly get both your testosterone and vitamin D levels checked. Chronic opiate use can really effect the levels of these and low test can have significant negative psychological symptoms. If you are experience these symptoms then both your positive and negative opiate use experience will not be as pleasant. I would certainly use a high quality multivitamin daily.

I'd consider attempting to stay on the lowest dose of methadone possible. If you're going to be using other opiates on top of it 60 actually sounds perfect.

My favorite many years ago was methadone and Xanax. But yes my line up was methadone, oxy and xan. Dangerous, especially if you are planning on adding all those street drugs on.

Your worrying me case.. be safe. Hope your well!

DS>OD

 

[caseface99]

thanks

 

[lovemissile66]

thanks, ill talk to my doctor about the testosterone thing. Also, my doctor told me that using is not only possible while on methadone but that the methadone will block overdoses is that true?

UH...ABSOLUTELY NO!!! QUITE THE OPPOSITE. YOU MAY BE TEMPTED TO UP THE AMOUNT OF FENT OR HEROIN OR WHATEVER, BECAUSE THE METHADONE BLOCKS THE EFFECT OF THE RECREATIONAL DRUG. HENCE, A POSSIBLE OVERDOSE. I USED TO IV HEROIN. I ALSO WENT THE METHADONE ROUTE, ALBEIT BRIEFLY. I WASN'T READY TO QUIT H AND SAW NO REASON TO PAY FOR BOTH.

METHADONE IS JUST AS PROBLEMATIC AS SUBOXONE WHEN TRYING TO COME OFF EITHER. I DON'T THINK I UNDERSTAND WHY YOU ARE ON METHADONE, EVEN WITH YOUR LEGAL SITUATION. IF YOU ARE STILL ABUSING STREET DRUGS, A DRUG TEST YOU MAY FAIL, METHADONE OR NOT.

 

[heliologean]

The methadone will increase your tolerance if you do it daily, but it won't stop overdoses like suboxone (generally) will. Methadone has a normal binding affinity for the mu opioid receptor so it won't "outcompete" other opiates you take like suboxone will. Using on methadone is dangerous, using on suboxone is significantly less dangerous (though still dangerous). Use caution please.

 

[neversickanymore]

The methadone will increase your tolerance if you do it daily, but it won't stop overdoses like suboxone (generally) will. Methadone has a normal binding affinity for the mu opioid receptor so it won't "outcompete" other opiates you take like suboxone will. Using on methadone is dangerous, using on suboxone is significantly less dangerous (though still dangerous). Use caution please.

You're on and off here.

To back earlier concerns I thought you should consider case

Methadone side effects, separating fact and fiction.

Low vitamin d status of patients in methadone maintenance treatment.

Methadone

Neuropathic Pain: Causes, Management and Understanding

Hypogonadism and Low Testosterone Levels as a Side Effect of Methadone and Buprenorphine
Hypogonadism in men receiving methadone and buprenorphine maintenance treatment.

Long-term Opioids Linked to Hypogonadism and the Role of Testosterone Supplementation Therapy - PMC

Opioids play a pivotal role in managing chronic pain with increasing prescription rates over the last few years. Hence, it is crucial to focus on the adverse effects of narcotics, and one of the lesser-known side effects is hypogonadism. Opioids act ...

www.ncbi.nlm.nih.gov

A comprehensive review of opioid-induced hyperalgesia - PubMed

Opioid-induced hyperalgesia (OIH) is defined as a state of nociceptive sensitization caused by exposure to opioids. The condition is characterized by a paradoxical response whereby a patient receiving opioids for the treatment of pain could actually become more sensitive to certain painful...

pubmed.ncbi.nlm.nih.gov

Methadone Injection: Package Insert / Prescribing Info

Methadone Injection package insert / prescribing information for healthcare professionals. Includes: indications, dosage, adverse reactions and pharmacology.

www.drugs.com

"Methadone has a normal binding affinity for the mu opioid receptor so it won't "outcompete" other opiates you take like suboxone will."

This isn't true. My Father had a patient brought to the ER that was a methadone pain patient that had taken Her entire monthly dose of methadone in an attempt to take her own life. It took almost the entire supply of narcan of THREE POPULATED COUNTIES to reverse the the OD successfully. This was early opiate crisis.. it wasn't available oc etc, but it clearly still shows how powerful methadone is. That statement is bs.. look it up yourself.

Neuropathic Pain: Causes, Management and Understanding
this link from above really goes into the other less known physiologic affects of methadone. I always wonder why some users scoff at methadone.. it's one hell of a powerful drug. I think it has to do with administration routes and addiction.

Totally true it won't save you from overdose.. Suboxone may help being a partial agonist with strong binding and the IV antagonist deterrent.

You can certainly use on top of methadone but it will be more expensive and dangerous as well.

 

[heliologean]

"Methadone has a normal binding affinity for the mu opioid receptor so it won't "outcompete" other opiates you take like suboxone will."

This isn't true. My Father had a patient brought to the ER that was a methadone pain patient that had taken Her entire monthly dose of methadone in an attempt to take her own life. It took almost the entire supply of narcan of THREE POPULATED COUNTIES to reverse the the OD successfully. This was early opiate crisis.. it wasn't available oc etc, but it clearly still shows how powerful methadone is. That statement is bs.. look it up yourself.

The binding affinity of methadone is ~ an order of magnitude smaller than the binding affinity of suboxone. On normal maintenance doses of suboxone literally all of your opiate receptors are occupied but only weakly activated, contrasted with normal methadone maintenance doses where some of your opiate receptors are occupied but fully activated. So on suboxone maintenance the only way to get high on opiates is to take something with a higher binding affinity, and that doesn't exist fortunately (or unfortunately).

I've had more than one friend switch to methadone for literally this reason and OD taking large doses of fent to breakthrough the opiate tolerance from the methadone. One of them died. The issue is that tolerance to the euphoria from opiates comes on faster/stronger than the tolerance to the respiratory depression does. Not saying methadone itself is bad just that if you're going to switch to methadone from suboxone for the purpose of being able to use/get high from other opiates, be cautious.

 

[neversickanymore]

link it up.. I didn't say methadone will prevent ODs.. so be careful as to your posts. you have to critically read before posting. So if methadone pushes over Suboxone and massive doses 0f narcan, how does your post make sense? The whole deal with Suboxone is what??? and its actually kinda bs as well.

 

[caseface99]

thansk

Not saying methadone itself is bad just that if you're going to switch to methadone from suboxone for the purpose of being able to use/get high from other opiates, be cautious.

That's exactly why I'm getting on methadone. Thanks for the responses. I'll be careful. I heard around 150 mgs wont block opiates so ill still be able to get high if I don't go over that dose. I started at 30 and I'm going up 10 per week.

 

[JackARoe]

I don’t know if this applies in 2025, but when I was on methadone in the early 80s into the 90s I did use on top of my dose at times. At least when it was 80 mg I could still feel whatever the NYC heroin was at that time over the methodone when IV’d. At that time the slogan was the heroin his so strong people are smoking it. However, saying that I know it’s a completely different game these days. I understand fentanyl can cut through buprenorphine. So that type of game is completely different from what I was used to.

Whenever I went above 80 mg of methadone using any heroin came across a lot lighter. Again though the street scene is completely different from 35 years ago. I can’t even say what someone would shoot up in 2025.

Stay safe. I’m kind of grateful that I’m out of the whole scene.

 

[Aslifeburns]

So i leveled with my doctor recently who had me on suboxone after catching me abusing my oxy. I told them that i certainly wasnt going to quit drugs irregardless of what they say and do. i complained that i wont be able to use opiates while on suboxone and so in response they said i should switch to methadone because ill be able to get high on fentanyl and heroin and drugs like that while on methadone. started at 60mg. what dose will get me feeling gooder? im on a court order for prescriptions is why i was taking the suboxone.

 

[Aslifeburns]

I was on paper so I went to a methadone clinic also. I had no insurance so I paid cash dumbest thing I ever did. The withdrawals last weeks. Ya, I got counseling included which filled my aoda requirement but I would take withdrawal from fentanyl and heroin before ever touching methadone again. If it's court ordered to be in a program, jail is 100x worse withdrawing from methadone. Methadone also blocks at some level(can't remember exact level I was told) so you could OD. Have you tried gabapentin?