Snorting 7-OH

[Exs95]

So I've been snorting 7oh powder (400-600mg) a day for almost a yr now

this method only appears to work on certain powders.. specifcally the fluffy ones and noto the crystaline

but even some of the fluffy ones don't work,

I'm wondering if it has to do wih Psuedo in the powder? Is Psuedo more bioavailable via intranasal? or is the effects I'm getting from the 7oh?

I've tired pure 7oh and it doesn't work so it must be the Psuedo.?

 

[Helpmeescapethis]

Sounds like you answered your own question there! Also, ai highly recommend tapering down. I know a few individuals who have been through high dose 7-OH withdrawals and it sounds worse than my nitazene withdrawals.

 

[Tetrapharmakos]

Sounds like you answered your own question there! Also, ai highly recommend tapering down. I know a few individuals who have been through high dose 7-OH withdrawals and it sounds worse than my nitazene withdrawals.

SR-17018 works amazingly well for reducing tolerance, just as great as it is for getting thru detox without any acute withdrawals.

But if you do decide to use SR-17018, please be careful using opiates again afterwards... 7-oh should be safer due to less respiratory depression, but people have ended up ODing after using SR-17018 and then using their usual opiate at a dose they were comfortable with before. It seems to massively rewind tolerance to near baseline within about a week if your using only the SR-17018 everyday without any other opiates.

 

[SuperPsych]

SR-17018 works amazingly well for reducing tolerance, just as great as it is for getting thru detox without any acute withdrawals.

But if you do decide to use SR-17018, please be careful using opiates again afterwards... 7-oh should be safer due to less respiratory depression, but people have ended up ODing after using SR-17018 and then using their usual opiate at a dose they were comfortable with before. It seems to massively rewind tolerance to near baseline within about a week if your using only the SR-17018 everyday without any other opiates.

That stuff sounds super interesting. I've heard a lot of stories of people having great success with it. I'm currently on buprenorphine. Gonna do the sublocade shot either at my next appointment in 2 weeks or push it out another month. Been thinking of getting some SR-17018 while it's available. I haven't used hard opiates in quite some time but have had an ongoing battle with kratom. Basically a constant cycle of using kratom daily in wild doses, detoxing, be sober for a while, back to the kratom. This has been going on for years. Is SR-17018 like Suboxone where it takes away the effects of withdrawal? Like would you be able to cold turkey and use SR-17018 and be fine? Or do you need to taper the opiate of choice while adding on SR-17018?

 

[Tetrapharmakos]

To my knowledge, for myself personally and most others they've been able to fully switch from usual. Opiate to the SR-17018 with success..occasionally people have some trouble switching over, this seems more common with 7-oh for some reason, and they have a better time starting the SR-17018 alongside a rapid taper of usual opiate, maybe 25% reduction per day for 3 days then switch fully to the SR-17018

 

[Exs95]

Sounds like you answered your own question there! Also, ai highly recommend tapering down. I know a few individuals who have been through high dose 7-OH withdrawals and it sounds worse than my nitazene withdrawals.

Ya that's my plan I have 1 8mg strip of subs I'm going to use when I drop my dose down. I've only ever been dependent on Kratom leaf, so I can't compare the W/Ds but not the first time I've heard the WD is worse than Fent & Zenes

 

[Exs95]

To my knowledge, for myself personally and most others they've been able to fully switch from usual. Opiate to the SR-17018 with success..occasionally people have some trouble switching over, this seems more common with 7-oh for some reason, and they have a better time starting the SR-17018 alongside a rapid taper of usual opiate, maybe 25% reduction per day for 3 days then switch fully to the SR-17018

to be honest i'd like to try the SR-17018 before I go the sub route

but someone I know it took him 3 grams of it for him to get off a high dose of 7..

 

[Tetrapharmakos]

to be honest i'd like to try the SR-17018 before I go the sub route

but someone I know it took him 3 grams of it for him to get off a high dose of 7..

That sounds about right. I think for the vast majority of people regardless of which opiate they are taking, 5 grams should be enough in most cases for a full detox, and with a little bit of SR-17 left over just Incase.

Dose range of 25 mg - 125 mg roughly, taken every 8-12 hours or 2x-3x per day, for a duration of 1.5 weeks-3 weeks.

That's a bit of a range but everyone is different.

 

[4DQSAR]

I've posted about SR-17018 elsewhere.

I think I concluded that the fact it's now being sold as an RC might suggest that in human trials, there were isssues. Why do I say that? Because pharmacutical companies are not legally required to publish a trial if it shows the drug in a bad light.

That's why I support www.alltrials.net

Because real harm is needlessly occuring because researchers do not have access to previous data sets.

BTW NO - I am in no way, shape or form connected to All Trials beyond once having shaken the hand* of Dr. Ben Goldacre who began this campaign some twenty years ago.

*It was connected to his body at the time - I'm not odd.

 

[Exs95]

I've posted about SR-17018 elsewhere.

I think I concluded that the fact it's now being sold as an RC might suggest that in human trials, there were isssues. Why do I say that? Because pharmacutical companies are not legally required to publish a trial if it shows the drug in a bad light.

That's why I support www.alltrials.net

Because real harm is needlessly occuring because researchers do not have access to previous data sets.

BTW NO - I am in no way, shape or form connected to All Trials beyond once having shaken the hand* of Dr. Ben Goldacre who began this campaign some twenty years ago.

*It was connected to his body at the time - I'm not odd.

Yeah tbh SR goes for like 99$ a G, I can't afford that atm. I'm just going to CT when the time comes and if I really need to I'll take the suboxone strip I have. I'm just nervous the Subs will just make it worse... never really been down this road. I know I can't taper because having it on hand makes me compulsively dose. So CT quit with a bunch of comfort meds like Pregabalin, Gabapentin, Soma, Diazepam and MIT extract or leaf

 

[4DQSAR]

Yeah tbh SR goes for like 99$ a G, I can't afford that atm. I'm just going to CT when the time comes and if I really need to I'll take the suboxone strip I have. I'm just nervous the Subs will just make it worse... never really been down this road. I know I can't taper because having it on hand makes me compulsively dose. So CT quit with a bunch of comfort meds like Pregabalin, Gabapentin, Soma, Diazepam and MIT extract or leaf

To be fair, the synthesis is not trivial. I suggest that at least to begin with, the chemists most likely only synthesized the drug at bench-scale because they could not be certain if it would be popular.

I believe SR-17018 was trialled in a primate in vivo model and I suggest the pertinent detail is 'Low In Vivo Efficacy'. If memory serves, in comparison with buprenorphine, the latter was statistically better in terms of pain relief as well as for opioid detoxification.

I know BLers have posted reports that noted that at around 100mg the compound (whose identity we cannot be certain of) produced 'typical opioid effects'. I suggest that trip reports are akin to unstructured case studies so of potential value, case studies can only ever be considered low quality evidence.

But if it can be subject to abuse, it WILL be subject to abuse.

I've known multiple people in the US who managed to use kratom tea to manage AWS and most reached a point where they began to consider if that morning tea they consumed was really needed.

But using large doses of 7-OH mitragynine (and possibly mitragynine pseudoindoxyl) does not sound compatible with a healthy lifestyle. If you don't even really know what you are consuming, obviously that's a bad thing.

I'm uncertain if SR-17018 is a panacea or merely another example of a partial agonist. There certainly is data showing that in primate models, changes in body chemistry (hyperaglasia) were noted. I have posted all of the papers and references but you know what? I forget where. I assume using keywords would locate it.

 

[Exs95]

To be fair, the synthesis is not trivial. I suggest that at least to begin with, the chemists most likely only synthesized the drug at bench-scale because they could not be certain if it would be popular.

I believe SR-17018 was trialled in a primate in vivo model and I suggest the pertinent detail is 'Low In Vivo Efficacy'. If memory serves, in comparison with buprenorphine, the latter was statistically better in terms of pain relief as well as for opioid detoxification.

I know BLers have posted reports that noted that at around 100mg the compound (whose identity we cannot be certain of) produced 'typical opioid effects'. I suggest that trip reports are akin to unstructured case studies so of potential value, case studies can only ever be considered low quality evidence.

But if it can be subject to abuse, it WILL be subject to abuse.

I've known multiple people in the US who managed to use kratom tea to manage AWS and most reached a point where they began to consider if that morning tea they consumed was really needed.

But using large doses of 7-OH mitragynine (and possibly mitragynine pseudoindoxyl) does not sound compatible with a healthy lifestyle. If you don't even really know what you are consuming, obviously that's a bad thing.

I'm uncertain if SR-17018 is a panacea or merely another example of a partial agonist. There certainly is data showing that in primate models, changes in body chemistry (hyperaglasia) were noted. I have posted all of the papers and references but you know what? I forget where. I assume using keywords would locate it.

Well I know what I'm using just not too sure what is causing most of the effects I experience, the 7oh or the Psuedo.

I'm quitting this week and I think it will be easy with everything I currently have at my disposal

 

[Biomed Tech Guy]

Well I know what I'm using just not too sure what is causing most of the effects I experience, the 7oh or the Psuedo.
I'm quitting this week and I think it will be easy with everything I currently have at my disposal

PLEASE let me..us know how it's going!!
I had got up to roughly 900-1200mg of 7OH with 55-70mg of pseudo every 24 hours, some days a bit more and some a bit less.
If SR-17018 can get me down off of near that (I've tapered that kratom down and Rx oxy ir and morphine er way up in the last 12 days) it will literally be a Godsend.
To be able to un-fuck myself from that level without making the national news or the obits, or to have a psych ward hang my picture on the wing, or a rehab facility refer to "my story" to make a point, and if I get a noticeable RESET on top of that....
I'm searching this forum for SR-17018 reports every day.

 

[DieTrying]

PLEASE let me..us know how it's going!!
I had got up to roughly 900-1200mg of 7OH with 55-70mg of pseudo every 24 hours, some days a bit more and some a bit less.
If SR-17018 can get me down off of near that (I've tapered that kratom down and Rx oxy ir and morphine er way up in the last 12 days) it will literally be a Godsend.
To be able to un-fuck myself from that level without making the national news or the obits, or to have a psych ward hang my picture on the wing, or a rehab facility refer to "my story" to make a point, and if I get a noticeable RESET on top of that....
I'm searching this forum for SR-17018 reports every day.

ANY sr info--success stories PLEASE let me know?

 

[4DQSAR]

any luck with paperers info -on sr? availability staeside? evry1 on discord which im new too seems to scamming pple-i had 30k stolen during covid by my half niece who was my 'payee'so i cant afford to be scammed i live month to month now on 966 a month ssdi-any help WOULD BE LIFECHANGING im in dire straights with the ban 7 -59yo and health stuff an abrupt wd cld literally kill me---

As gar as I can tell, SR-17018 is quite expensive to make. One of the main precursors has no other uses (as far as I know) so there must be a temptation for people to cash in by selling something like brorphine. I'm uncertain how orally active this latter compoud is but long ago when I read the Chinese papers, I seem to remember the two having similar oral activity. But was long ago, so I could be wrong on that,

 

[VerbalTruist]

@DieTrying I would recommend a trip to detox if you’re worried about dying from withdrawal. As far as asking for sources goes, it’s against the rules and knock it off.

 

[DieTrying]

@DieTrying I would recommend a trip to detox if you’re worried about dying from withdrawal. As far as asking for sources goes, it’s against the rules and knock it off.

did i ask for sources? ill have to go read back -bcs if so i certainly didnt mean to-more likey was in partial wd and panic post/thinking out loud-oh yes i see it-sorry-gonna delete it-

 

[4DQSAR]

any luck with paperers info -on sr? availability staeside? evry1 on discord which im new too seems to scamming pple-i had 30k stolen during covid by my half niece who was my 'payee'so i cant afford to be scammed i live month to month now on 966 a month ssdi-any help WOULD BE LIFECHANGING im in dire straights with the ban 7 -59yo and health stuff an abrupt wd cld literally kill me---

Mate - I'm sure it wouldn't take long to find the thread. I posted links, the problem is that I have posted literally THOUSANDS of links to academic papers and I also only have a finite amount of life left to live. If it's is 'LITERALLY lifesaving', find it. I don't think it's my job to act as a oracle. It's on the site, alost certaily in either opioids or other drugs. But I don't keep all of those papers. I just find them when someone asks the first time. From that point, it's up to the seeker.

Sorry, it's been a long day and it isn't like I don't have others who also seek aid.

 

[DieTrying]

@DieTrying I would recommend a trip to detox if you’re worried about dying from withdrawal. As far as asking for sources goes, it’s against the rules and knock it off.

thankswish i could go get medical manage/moniterd--if i could afford detox id have went a year ago-tho' thats how i ended up on 7 to avoid an abrupt forced taper by new young doctor pullinh my script of 10 yeras--i al,msost got taken out jumping off 4 mg subs in 2007 dropped to 92 lbsfrom 145 in less then 2 weeks -tachycardia for over a month severe dehydration stec all while passing kidney stones/pain adrenaline insonia-and sub wd-im older now and have signalling autonomid issues and metabolic so im in even worse positon than in 2007-medically- i live alone dont even have a way to hospital-ambulance takes 45 minutes to get to my aprtment -so just trying to not die is all

 

[Biomed Tech Guy]

I had a "random" (that my Spirit doesn't take as random) conversation w/a guy a couple of days ago. It started out and encompassed work and vacation, but pain management and WD came up.
He said the 1x a month injectable Sublocade was eventually his ticket to freedom. NOT the sublingual strips, but the injection. FWIW