placebonaut
Bluelighter
- Joined
- Feb 7, 2026
- Messages
- 495
There's plenty of info out there about threshold vs strong dosage of drugs per body weight, and info on LD50, however people have different body chemistry and drugs effect them in different ways, there's a bit of a gamble building up and balancing dosage with tolerance changes as usage increases to remain safe.
I wondered for the popular drugs if there are also common physiological, mental, and/or psychological traits that can help people notice where they are on the range of intoxication through to risk to life, especially early warning signs people are getting close to death! Maybe also risk to dependency/addiction.
I've seen bits of info scattered around usually during drug specific discussion, but can't find any general discussion on the warning signs to watch out for.
A few examples to illustrate the point
Anyone else have any other examples that can be used as early warning signs - they might not be the same for everyone but if people are aware they'd have a little alarm bell of warning that might go off in their head to help them stay safe.
I wondered for the popular drugs if there are also common physiological, mental, and/or psychological traits that can help people notice where they are on the range of intoxication through to risk to life, especially early warning signs people are getting close to death! Maybe also risk to dependency/addiction.
I've seen bits of info scattered around usually during drug specific discussion, but can't find any general discussion on the warning signs to watch out for.
A few examples to illustrate the point
- Soma - When I'm approaching my strong dosage of Soma I tend to nod out, there seems linkage with the dose and duration of the nodding, lower dose nods me for 15 mins, higher dose 30 mins, higher still and I hit the soma shuffle phase once I come round from the longer nod
- Cocaine + Alcohol - when I start to over do the cocaine dose I get jittery, it's always time to back off then
- Increased dosage - taking more to get the same high is an indication off tolerance build up and should be a sign to consider a tolerance break
Anyone else have any other examples that can be used as early warning signs - they might not be the same for everyone but if people are aware they'd have a little alarm bell of warning that might go off in their head to help them stay safe.
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