asecin
Bluelighter
- Joined
- Apr 13, 2005
- Messages
- 1,725
http://en.wikipedia.org/wiki/Topoisomerase_inhibitor
Topoisomerase inhibitors are agents designed to interfere with the action of topoisomerase enzymes[1] (topoisomerase I and II), which are enzymes that control the changes in DNA structure[2] by catalyzing the breaking and rejoining of the phosphodiester backbone of DNA strands during the normal cell cycle.
Numerous plant derived natural phenols (ex. EGCG,[6][7][8][9][10] genistein, quercetin, resveratrol) possess strong topoisomerase inhibitory properties affecting both types of enzymes. They may express function of phytoalexins - compounds produced by plants to combat vermin and pests.
few examples out of vast polyphenol compounds out there present in herbs, fruits and vegetables.
Use of topoisomerase inhibitors for antineoplastic treatments may lead to secondary neoplasms because of DNA damaging properties of the compounds. Also plant derived polyphenols shows signs of carcinogenity, especially in feuses and neonates who do not detoxify the compounds sufficiently.[11][12][13] An association between high intake of tea (containing polyphenols) during pregnancy and elevated risk of childhood malignant central nervous system (CNS) tumours has been found
just one example of a confirmed type of tumor occuring when consuming polyphenols from either herbs, fruits or vegetables.
for ease, ill pick on a popular one.
http://en.wikipedia.org/wiki/Epigallocatechin_gallate
This property might be responsible for observed anticarcinogenic effects; however, there is also a carcinogenic potential. High intake of polyphenolic compounds during pregnancy is suspected to increase risk of neonatal leukemia. Bioflavonoid supplements should not be used by pregnant women.[25][26][27] Maternal consumption of tea or coffee during pregnancy may elevate the risk of childhood malignant central nervous system (CNS) tumours through unknown mechanisms.[
since its wikipedia, its not possible to have all the info available just in one article, but i have read medical journals relating flavonoids and polyphenols (present in fruits and vegetables at high amounts) to be responsible for more than the one here stated here type of tumor in new borns. and if required, i might have to waste few hours finding urls i used to save all around folders.
my question is, why are there no warnings on fruit and vegetable consumption that warns pregnant women not to eat them ?? it really pisses me off that marketers of "natural" products deceive, if not already healthy people who can metabolize them effectively, at least pregnant women ? thats low.
Topoisomerase inhibitors are agents designed to interfere with the action of topoisomerase enzymes[1] (topoisomerase I and II), which are enzymes that control the changes in DNA structure[2] by catalyzing the breaking and rejoining of the phosphodiester backbone of DNA strands during the normal cell cycle.
Numerous plant derived natural phenols (ex. EGCG,[6][7][8][9][10] genistein, quercetin, resveratrol) possess strong topoisomerase inhibitory properties affecting both types of enzymes. They may express function of phytoalexins - compounds produced by plants to combat vermin and pests.
few examples out of vast polyphenol compounds out there present in herbs, fruits and vegetables.
Use of topoisomerase inhibitors for antineoplastic treatments may lead to secondary neoplasms because of DNA damaging properties of the compounds. Also plant derived polyphenols shows signs of carcinogenity, especially in feuses and neonates who do not detoxify the compounds sufficiently.[11][12][13] An association between high intake of tea (containing polyphenols) during pregnancy and elevated risk of childhood malignant central nervous system (CNS) tumours has been found
just one example of a confirmed type of tumor occuring when consuming polyphenols from either herbs, fruits or vegetables.
for ease, ill pick on a popular one.
http://en.wikipedia.org/wiki/Epigallocatechin_gallate
This property might be responsible for observed anticarcinogenic effects; however, there is also a carcinogenic potential. High intake of polyphenolic compounds during pregnancy is suspected to increase risk of neonatal leukemia. Bioflavonoid supplements should not be used by pregnant women.[25][26][27] Maternal consumption of tea or coffee during pregnancy may elevate the risk of childhood malignant central nervous system (CNS) tumours through unknown mechanisms.[
since its wikipedia, its not possible to have all the info available just in one article, but i have read medical journals relating flavonoids and polyphenols (present in fruits and vegetables at high amounts) to be responsible for more than the one here stated here type of tumor in new borns. and if required, i might have to waste few hours finding urls i used to save all around folders.
my question is, why are there no warnings on fruit and vegetable consumption that warns pregnant women not to eat them ?? it really pisses me off that marketers of "natural" products deceive, if not already healthy people who can metabolize them effectively, at least pregnant women ? thats low.
