PlurPsyed
Bluelighter
A friend of mine just gave me a bottle of Seroquel saying it would be good for upper comedowns. Does anyone have any experience using it for this purpose? How effective it is and what's a good dosage for this purpose?
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OD Moderators: Keif’ Richards | negrogesic
Stimulants Seroquel for comedowns?
- Thread starter PlurPsyed
- Start date
Short answer, yes, long answer, read the pros and cons here.
Seroquel is an antihistamine at lower doses (25-100mg, but personally I would't take any more than 75mg) and doesn't become an antipsychotic until higher doses of 100mg+
The antihistamine effects are what causes the sedation, so you should aim for the dose in the range listed above if you are using it to help with the comedown but don't want to deal with the antipsychotic effects.
There are still some negative side effects to using it for this purpose, and you can read about them in the thread I linked you to. Personally I would only use it if I had nothing else around, and really needed to sleep. It can make it hard to think the next day, making you feel like a zombie, so if you have things to do that require attention and motor skills, I suggest using something else like benadryl (diphenhydramine) or unisom (doxylamine) for sleep. Benzos would be ideal, but I'm sure if you had those you wouldn't be asking about using seroquel. The other drugs are OTC so you can get them at any pharmacy or supermarket.
Seroquel is an antihistamine at lower doses (25-100mg, but personally I would't take any more than 75mg) and doesn't become an antipsychotic until higher doses of 100mg+
The antihistamine effects are what causes the sedation, so you should aim for the dose in the range listed above if you are using it to help with the comedown but don't want to deal with the antipsychotic effects.
There are still some negative side effects to using it for this purpose, and you can read about them in the thread I linked you to. Personally I would only use it if I had nothing else around, and really needed to sleep. It can make it hard to think the next day, making you feel like a zombie, so if you have things to do that require attention and motor skills, I suggest using something else like benadryl (diphenhydramine) or unisom (doxylamine) for sleep. Benzos would be ideal, but I'm sure if you had those you wouldn't be asking about using seroquel. The other drugs are OTC so you can get them at any pharmacy or supermarket.
PlurPsyed
Bluelighter
Thank you!
tricomb
Bluelight Crew
After binging on MDMA for many days once I took 25mg once and blacked out for 48 hours, got in a shitload of trouble. I could not form thoughts and had trouble speaking for days after.
Do not use seroquel if benzodiazepines are available. This should be your the last line of treament.
I will use thorazine or haloperidol before I use quetiapine again.
Do not use seroquel if benzodiazepines are available. This should be your the last line of treament.
I will use thorazine or haloperidol before I use quetiapine again.
ErgicMergic
Bluelighter
^Agreed, antipsychotics should not be used in non-psychotic people, imo.
tricomb
Bluelight Crew
It's like trying to hit a nail with a jack hammer. Or trying to drill a hole in the wall with an oil drilling apparatus.
ErgicMergic
Bluelighter
Seriously... unless he is prescribed it for meth addiction? Maybe the doctor thinks he might become psychotic during a binge and this is a "just in case" thing so you don't end up in the psych ward?
Stimulant psychosis = psychosis, and can be treated with anti-psychotics
Stimulant psychosis = psychosis, and can be treated with anti-psychotics
Captain.Heroin
Bluelight Crew
I don't know why anyone would willingly take seroquel.
the_ketaman
Bluelighter
Wow I am shocked at the replies in this thread. Ive been using Seroquel to sleep for years now in doses of between 25-200mg and ive never had a problem. I always use it after a night on the Meth or MDMA I find it does a great job at putting me to sleep. Never had any side effects, the only undesireable side-effects ive ever got from Seroquel is not being able to get up the next morning on time and being drowsy but its nothing a strong cup of coffee wont fix.
Why may I ask is everyone so against Seroquel?
Why may I ask is everyone so against Seroquel?
tricomb
Bluelight Crew
Because there are so many better options. Like benzos. I prefer Xanax or Halcion.
I don't like using it, but I've been using seroquel intermittently recently for insomnia...the other night I dosed about 100mg, and woke up 5 hours later, so I dosed another 150...I was prescribed it for an anti-depressant, but at the time it was causing too much sedation...I don't get it...I rarely use it, but I just build a tolerance to it and now sometimes it's the only thing that can get me to sleep...
I don't recommend using it if other options are available and viable (i.e. you can use doxylamine and you don't have an insane tolerance to these types of anti-histamines)...
I don't recommend using it if other options are available and viable (i.e. you can use doxylamine and you don't have an insane tolerance to these types of anti-histamines)...
eukaryote
Bluelighter
Yes, seroquel is quite effective for the come down from stimulants, it very effective at reducing the agitation, restlessness and insomnia. I would recommend a dose of 50m.g. in someone who does not take it regularly.
I am surprised at the posts in this thread! Seroquel is commonly Rx'ed for insomnia and general sedation. It is more effective then benzos in the case of stimulants due to its antagonist action on DA and 5HT. This is speaking from professional experience in treatment of persons presenting with stimulant related agitation, I prefer it over most other AP's due to its rather gentle side effect profile.
Really?!? Considering Haloperidol's tendency for adverse reactions including potentially lethal cardiac arrhythmias I would really suggest sticking to atypical APs if possible.
I am surprised at the posts in this thread! Seroquel is commonly Rx'ed for insomnia and general sedation. It is more effective then benzos in the case of stimulants due to its antagonist action on DA and 5HT. This is speaking from professional experience in treatment of persons presenting with stimulant related agitation, I prefer it over most other AP's due to its rather gentle side effect profile.
Really?!? Considering Haloperidol's tendency for adverse reactions including potentially lethal cardiac arrhythmias I would really suggest sticking to atypical APs if possible.
tricomb
Bluelight Crew
For my problems, atypicals don't cover it. But I do not medicate for many of my psychiatric conditions against doctors orders. I'm not dangerous to myself and I enjoy the real me.
I much prefer the older neuroleptics, since I am a VERY infrequent user of them.
Haloperidol is an amazing drug. Even 1-2mg is effective as fuckk.
I much prefer the older neuroleptics, since I am a VERY infrequent user of them.
Haloperidol is an amazing drug. Even 1-2mg is effective as fuckk.
the_ketaman
Bluelighter
If I take benzos on a comedown im more likely to stay awake to enjoy the combo of benzo+meth-comedown, it always feels so good to me. Seroquel just makes me feel sober for 15 minutes then really sleepy. For most people if what you want is to go to sleep then seroquel is the go, it is very safe too. But if you want to get a buzz out of it or for anxiety then I think a benzo would be more appropriate. Valium or Xanax would be my personal preference, simple yet effective.
Taking benzodiazepines on a daily base for sleep is simply not an option(tolerance etc). I take 75mg non XR for sleep together with 15mg diazepam at the moment.
invisigone
Greenlighter
- Joined
- Apr 9, 2012
- Messages
- 29
when i first took seroquel in the hospital (i was an inpatient when i was started to monitor the reaction/side effects) about 100mg daily was enough to send me real cloudy and i got very drunk on only 3 beers 
however, if taken on a daily basis tolerance builds ridiculously fast, so if you are planning on getting the same effect for more than a couple of weeks i would look elsewhere.
to give you some idea, i weigh 210lb (body weight is a factor) within the space of 2 months i was able to tolerate 900mg daily and i get no sedative effects whatsoever to the point the shrink has had to prescribe me ambien and thorazine just to make me sleep. the point i'm making is that tolerance builds quick, that being said, a friend of mine took a 200mg pill because he couldn't sleep and was out of it for 3 days, he didn't like it much he never wanted another (i guess one man's meat really is another man's poison)
my two cent's worth: used occasionally it is pretty good for chillin/sleep. you'd be far better of with a benzo tho, it's nasty shit and why anyone would take it if they had a choice is beyond me.
however, if taken on a daily basis tolerance builds ridiculously fast, so if you are planning on getting the same effect for more than a couple of weeks i would look elsewhere.to give you some idea, i weigh 210lb (body weight is a factor) within the space of 2 months i was able to tolerate 900mg daily and i get no sedative effects whatsoever to the point the shrink has had to prescribe me ambien and thorazine just to make me sleep. the point i'm making is that tolerance builds quick, that being said, a friend of mine took a 200mg pill because he couldn't sleep and was out of it for 3 days, he didn't like it much
he never wanted another (i guess one man's meat really is another man's poison)my two cent's worth: used occasionally it is pretty good for chillin/sleep. you'd be far better of with a benzo tho, it's nasty shit and why anyone would take it if they had a choice is beyond me.
JJ-180
Bluelighter
And what's wrong with Etizolam? Freely available, much shorter half-life than most benzos and a fantastic hypnotic.