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Opioids Serious problems with sleep and opiates.

boomhs

Bluelighter
Joined
Dec 19, 2010
Messages
221
Ok i'll just start off saying what meds i take for depression (in case it's related, i think not).
per day - anafranil 150mg, depakine chrono 1000mg, diazepam 20mg, Seroquel insta release 100mg (to sleep)

Ever since i started doing opioids (so far i only did dilaudid and oxycontin) ocasionally i have serious issue when it's sleep time. Even having only taken e.g. 20mg Oxy 6 hours ago when it's time to fall asleep i feel my blood pressure go low, breathing too, feels so bad i wake up when i'm almost falling asleep. Taking sugar seems to help.
It's so horrible, and i feel when this post opioid window of weird feelings when i'm about to doze off it's like a blanket of weirdness is going away and i instantly know "now i can sleep".

I find this shit weird since people take strong opioids and fall asleep like heroin. I tried not taking benzos that day and same thing.

Thx.
 
Well, usually people have sleep issues with opiods when dosing too close to bedtime, especially with oxycodone (since many find it stimulating). However, you said you wait at least six hours? Try taking it even eariler before that...and I know you hate to hear this but....do you really HAVE to take opiates? If you really want to take them much eariler and try to stick with more sedating ones like morphine or codeine and you should be able to sleep better.
 
Well, usually people have sleep issues with opiods when dosing too close to bedtime, especially with oxycodone (since many find it stimulating). However, you said you wait at least six hours? Try taking it even eariler before that...and I know you hate to hear this but....do you really HAVE to take opiates? If you really want to take them much eariler and try to stick with more sedating ones like morphine or codeine and you should be able to sleep better.

Thx. Well i actually am basically an alcoholic, at least atm. And as i did once before i'm using opiates for a while, once i'm done i'll have no cravings for alcohol, also anafranil will have started to work more (alcohol fucks up its effect). So i plan to stop soon, clean of opiates and alcohol (I won't be stupid enough to start drinking again after since the cravings will be gone.)

So it's not as i'm doing this totally for fun (well it does feel good man :p). Still it lowers my respiration so much goddamn... Was worst when i was IV'ing Dilaudid sometimes few hours before bedtime, i rly thought i was gonna die.
Can you die actually from lowered respiration if you fall asleep?
 
EDIT: just saw your latest post while I was typing this one. Are you drinking as well as taking all the other stuff?! TAke it easy man!!

Hi Boomhs:)

Do you have much tolerance to opiates/opioids?

If you're taking seroquel and diazepam already, adding oxy on top would make for some pretty powerful respiratory depression I would imagine. Do you feel quite stoned after taking the oxy? I mean, before you lie down?

Perhaps it's too much for your system to handle. Seroquel is pretty potent stuff. And diazepam on top of that.... then with a potent opioid like oxy... that's a dangerous mix.

Even if you skip the diazepam for one day when you take oxy there will still be lots of that benzo in your system because diaz has a VERY long half-life and will still interact with any opiates you take.

Take care.
 
EDIT: just saw your latest post while I was typing this one. Are you drinking as well as taking all the other stuff?! TAke it easy man!!

Hi Boomhs:)

Do you have much tolerance to opiates/opioids?

If you're taking seroquel and diazepam already, adding oxy on top would make for some pretty powerful respiratory depression I would imagine. Do you feel quite stoned after taking the oxy? I mean, before you lie down?

Perhaps it's too much for your system to handle. Seroquel is pretty potent stuff. And diazepam on top of that.... then with a potent opioid like oxy... that's a dangerous mix.

Even if you skip the diazepam for one day when you take oxy there will still be lots of that benzo in your system because diaz has a VERY long half-life and will still interact with any opiates you take.

Take care.

Nono not drinking, taking this to help stop actually, it does work in helping. I feel the normal Oxy high i guess, feeling good and such.

I tried not taking Seroquel and the night plus not the diazepam 10mg and still i feel like shit. Meh, maybe nothing to do.
 
Can you die actually from lowered respiration if you fall asleep?

Absolutely. This is what sounds alarm bells for me when I read about the potent meds you're taking.

As I mentioned, even if you skip this or that for a day, that's still a lot of potent CNS depressant action going on in your body. That feeling you get when you're going to sleep.... I know that, too. It's not good, is it? You're right to be concerned. Your body and mind know the difference between feeling really stoned and sleepy and drifting VS feeling like a slab of cold concrete which is about to slip off into oblivion.

I know it's hard to get off alcohol and you'll be looking for substitutes to make it bearable, but tread carefully. You want to be around for the recovery, right?

Take care and good luck. Let us know how you get on.
 
"Even having only taken e.g. 20mg Oxy 6 hours ago when it's time to fall asleep i feel my blood pressure go low, breathing too, feels so bad i wake up"

This is the number 1 rule that you are using too much...be careful
 
It's probably the seroquel or the interaction with it.

Ima reduce seroquel, been tired of it so long. Now i'm at 100mg and want to go lower. I'm not bipolar i just take it to sleep and have been... for like 6 years now. Max dosage was 300mg at a time, and it was like - don't take it, don't sleep. Now i think my body is so used to it i can sleep without it. Still i hear it's a bitch of a pill to quit.

I'm getting my hands on good #4 heroin soon, for the 1st time an opioid not an opiate! I hear it messes with the buzz of both, plus my "hellish time" when I need to go to bed and can't breathe and feel like crap, so i'm motivated.
 
I'm getting my hands on good #4 heroin soon, for the 1st time an opioid not an opiate! I hear it messes with the buzz of both, plus my "hellish time" when I need to go to bed and can't breathe and feel like crap, so i'm motivated.

Just FYI, I think you meant it'll be your first time with an opiate instead of an opioid (opioids are synthetic.) In terms of the sleep, I'd doubt (personally) that it's due to the oxy in your system. This may sound dumb, but have you noticed a difference in the sleep onset if you've taken the oxy SOONER than 6 hours before you go to bed? Like let's say 3 hours beforehand for the sake of argument?

If it's the oxy that's causing you trouble falling asleep, then this will prove that, but it's also possible it could be a sort of rebound effect from the medication wearing off. Also, the seroquel as others have said will add to the CNS depression as will the benzos, so keep that in mind too. Have you tried anything besides seroquel for sleep? If you're only on it for insomnia, I'd recommend switching to something like trazodone or diphenhydramine instead. I don't think seroquel is a very appropriate sleep aid if others sleep meds of a lesser pharmacological caliber have not been tested and failed before prescribing seroquel, but that's just my opinion.

Have you noticed if maybe you've started to drink more caffeine than usual with the oxycodone in order to prevent drowsiness / "nodding" effects? If so, you could be digesting the caffeine slower than others, which would make sleep obviously more difficult.

Also, more simply, have you tried reducing the oxy dosage to say 10mg and taking 5-10mg of your diazepam with it instead of taking it at night? (if thats what you do.) This could help give you the same overall feeling by potentiating the oxy while also reducing the CNS-depression that could be causing anxiety and making it more difficult to sleep.
 
I used to have the same effect with sleep when I was still using opiates. I could not sleep if I had dosed any kind of opioid/opiate in the later part of the day. Opiates always gave me energy and made me really talkative, more so than stimulants. I think that's your problem, so don't worry too much about other substances causing your insomnia.
 
Just FYI, I think you meant it'll be your first time with an opiate instead of an opioid (opioids are synthetic.) In terms of the sleep, I'd doubt (personally) that it's due to the oxy in your system. This may sound dumb, but have you noticed a difference in the sleep onset if you've taken the oxy SOONER than 6 hours before you go to bed? Like let's say 3 hours beforehand for the sake of argument?

If it's the oxy that's causing you trouble falling asleep, then this will prove that, but it's also possible it could be a sort of rebound effect from the medication wearing off. Also, the seroquel as others have said will add to the CNS depression as will the benzos, so keep that in mind too. Have you tried anything besides seroquel for sleep? If you're only on it for insomnia, I'd recommend switching to something like trazodone or diphenhydramine instead. I don't think seroquel is a very appropriate sleep aid if others sleep meds of a lesser pharmacological caliber have not been tested and failed before prescribing seroquel, but that's just my opinion.

Have you noticed if maybe you've started to drink more caffeine than usual with the oxycodone in order to prevent drowsiness / "nodding" effects? If so, you could be digesting the caffeine slower than others, which would make sleep obviously more difficult.

Also, more simply, have you tried reducing the oxy dosage to say 10mg and taking 5-10mg of your diazepam with it instead of taking it at night? (if thats what you do.) This could help give you the same overall feeling by potentiating the oxy while also reducing the CNS-depression that could be causing anxiety and making it more difficult to sleep.

Yeah i meant 1st time with opiate. Yes i'm sure it's the oxy/dilaudid, back when i shot dillies sometimes i'd shoot too close to sleeptime and then couldn't and then when i went too bed would nod off and wake up feeling like i was about to die and breathing almost nothing it was horrible.
I'll talk to my doctor about those 2 meds as yes i take seroquel only to sleep aid.
I think the problem is mostly seroquel and maybe a little bit diazepam too. I have tried not taking diazepam at all and still had it. Even tried not taking seroquel for a night and still had the respiratory problem, but i guess seroquel stays in the system and skipping 1 pill won't matter. I do take coffee, helps lot's of things.

I used to have the same effect with sleep when I was still using opiates. I could not sleep if I had dosed any kind of opioid/opiate in the later part of the day. Opiates always gave me energy and made me really talkative, more so than stimulants. I think that's your problem, so don't worry too much about other substances causing your insomnia.

Nono i don't have insomnia or inability to sleep because i'm too active and excited. I can be really tired and even nod off, but i wake up feeling horrible and like i was about to stop breathing, i guess the body feels something wrong and wakes you up. I think i might have died if i was unlucky back when i shot dillies twice a day.

Thx all
 
Your comment about sugar helping made me think that on top of the possibility of respiratory depression and interaction with all the other stuff you're taking, it could have something to do with a decrease in blood glucose levels. I've been doing a little research into it lately as I seemed to be having blood sugar swings while on the Heroin I had recently been doing and there appears to be some indication that with certain patients Opioids/ates can cause unpredictable variations in blood glucose levels. But it's just a thought.
 
Maybe try adjusting your pillow or raising the back of your bed a bit. I've had problems like you describe just from trying to sleep while really high on weed.
 
Hm that sucks. I'm working out a lot so also doesn't help. And i'm trying to cut down down on all sugar since it's the #1 important thing in a diet and (glucose+frutose=sugar). Still i think Seroquel is the main thing fking me up.
 
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