you can do a CWE. apap is insoluble in cold water, and hydrocodone is so it is easy to separate the two. you can do a quick google search or just do a search on BL...there are so many threads on it...
but i dont understand your thread really? are you asking if it is ok to take 2500mgs apap at once? or are you saying that you cant even take 500mgs apap without getting sick?? CWE removes most, but not all of the apap so that might not even help if you get sick from only 500mgs apap. maybe you could "trade" them away and get some roxicodone (which is oxycodone with no apap)
while 2500mgs will not kill you, it certainly isnt great for your liver. yes, i have taken that much at once before and i am perfectly fine with no liver problems, but people are different and i don't know how many drugs you have put into your body in the past, health issues, ect...