• N&PD Moderators: Skorpio

Selegiline + Wellbutrin

hey jcee, that is great news that you were able to cut ur xanax dose by such a large proportion due to the selegiline. Try to establish good routines and habits now while you can, because the effect of the selegiline will EVENTUALLY wear off, and u will need to rely upon those habits that u have established during its period of efficacy.

Thanks. I will keep that in mind as I wasn't aware of that property with selegiline. I had to take 150mg Seroquel last night as I couldn't sleep but managed to get 6 hrs. I may try to skip selegiline today and start with 1.25 tomorrow. I am sensitive to stimulants. That sucks as coffee or any other effects me, hence the xanax. I have trazodone and am going to try to mix as to not take Seroquel every night. I don't like that I have to take 150 mg.

Thanks
 
Okay. We're confusing ethical responsibility, prudent management of one's own actions, and reliable causal patterns. :) Moot point though.
...
I had good experiences on selegiline. It's subtle, though, and after a couple of months, I stopped really noticing it. No withdrawal with cessation, of course.

ebola

I agree, it is subtle.I can barely notice a difference, I may stop taking it since the effect is weak for me. THe wellbutrin seems to work much better
 
wellbutrin isnt even very good.

im amazed at the potency shift between bupron and clen (given the similarity in their molecular structure).
 
I'm finding selegiline crap and bupropion crap in the past.

I just wish I could get my hands on some real drugs.
 
hey guys i am new here. i dont know if this forum is really for getting fucked up or for well being... but i was searching for discussions about taking wellbutrin and selegiline together.

i have taken them both seperately in the past, and together. I found the wellbutrin xl at 300mg was more powerful then the effects from the 2.5mg of selegiline (all dosing are 1x daily).

i take 2.5mg seligiline daily, ongoing non stop for its boost to dopamine and health benefits at low dosage over time (at least according to studies). The wellbutrin i take for concentration/combat fatigue. I have noticed that every time i start wellbutrin i love it at first, then get off it due to feeling spacey.

so i started it up again a few days ago:
i am currently taking 300mg welly and 2.5mg dep daily. i have energy all day, i yawn more(strange), feel slightly sleepyheaded/fazed most of the time (not as clear minded) but its soooo slightly. all in all though, im more talkative, attentive, and focused. in fact i would never have researched this thread and wrote this post if i wasnt on wellbutrin (catch 22, but stfu u know what i mean). i also found my aggression has increased, much more than being on testosterone injections...

anyway does anyone see this as likely being dangerous? i notice when i take a caffeine/ephedrine i twitch a little and feel racy. Im guessing this is because im already stimulated enough from the other shit, and i should lay off stimulants while on this combo? i will until further notice at least...

i feel like this should be safe, due to the fact that wellbutrin can be increased to 450, which is 150mg more than im taking. and the fact that selegiline is taken in much higher dosages, in a patch which i would assume would increase absorption, compounding how much stronger it is.

i feel it is safe, but i want to know your opinions. please dont give me your opinion if you dont have a thorough understanding of endocrinology and such, or a solid background with drug combinations and effects.

well that was really long and im guessing it made no sense and nobody will reply. oh well. i also notice that i am soo smiley, and things make me laugh more, and i love petting my cat more, and i enjoy working out more... its pretty cool...

stats: 24 years old, 200lbs, 15%bf, 5'11" (so you can get an idea of dosing) and if you havent guessed it i am male. hear me roar.
 
hey guys i am new here. i dont know if this forum is really for getting fucked up or for well being... but i was searching for discussions about taking wellbutrin and selegiline together.

i have taken them both seperately in the past, and together. I found the wellbutrin xl at 300mg was more powerful then the effects from the 2.5mg of selegiline (all dosing are 1x daily).

i take 2.5mg seligiline daily, ongoing non stop for its boost to dopamine and health benefits at low dosage over time (at least according to studies). The wellbutrin i take for concentration/combat fatigue. I have noticed that every time i start wellbutrin i love it at first, then get off it due to feeling spacey.

so i started it up again a few days ago:
i am currently taking 300mg welly and 2.5mg dep daily. i have energy all day, i yawn more(strange), feel slightly sleepyheaded/fazed most of the time (not as clear minded) but its soooo slightly. all in all though, im more talkative, attentive, and focused. in fact i would never have researched this thread and wrote this post if i wasnt on wellbutrin (catch 22, but stfu u know what i mean). i also found my aggression has increased, much more than being on testosterone injections...

anyway does anyone see this as likely being dangerous? i notice when i take a caffeine/ephedrine i twitch a little and feel racy. Im guessing this is because im already stimulated enough from the other shit, and i should lay off stimulants while on this combo? i will until further notice at least...

i feel like this should be safe, due to the fact that wellbutrin can be increased to 450, which is 150mg more than im taking. and the fact that selegiline is taken in much higher dosages, in a patch which i would assume would increase absorption, compounding how much stronger it is.

i feel it is safe, but i want to know your opinions. please dont give me your opinion if you dont have a thorough understanding of endocrinology and such, or a solid background with drug combinations and effects.

well that was really long and im guessing it made no sense and nobody will reply. oh well. i also notice that i am soo smiley, and things make me laugh more, and i love petting my cat more, and i enjoy working out more... its pretty cool...

stats: 24 years old, 200lbs, 15%bf, 5'11" (so you can get an idea of dosing) and if you havent guessed it i am male. hear me roar.

I would definately lay off caffeine/ephedrine on that combo. If you feel you need even more stimulation just drink copious amounts of tea throughout the day. The stimulation from camillia sinensis is not nearly as edgy, and is actually beneficial to your body and mind. Iced green tea with honey and ginseng is dirt cheap. Not sure of the quality, but it does the job for me. Please try this before upping your dose. If that fails you can try supplementing with DL-phenylalanine, which is reportedly a good adjunct to selegiline. It's a combination of the basic precursor to all endogenous phenethylamines (L-isomer), and breakdown inhibitor of enkephalins as an added bonus (D-isomer). L-tyrosine would be a worst option.

I'm not sure how to explain the increased yawning. As i understand it, it's the result of elevated dopamine or endorphin levels. Dopamine causes some bronchodilation (feels easier to breathe), so yawning comes more easily. Endorphins can trigger dopamine release indirectly.
 
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