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Selegiline + Wellbutrin

selegiline is rubbish, if u havent tried it yet i can promise that u are not missing much.
 
Smyth said:
selegiline is rubbish, if u havent tried it yet i can promise that u are not missing much.
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Depends on what your using it for. I am taking it for treatment resistant depression because the celexa and wellbutrin were pooping out on me and I didn't want to risk the seizure risks of the 300mg dose. It also takes a few weeks to kick in. So my doc added 2.5 of selegiline 3 times a week to help boost me. He said the "washout-period" should only be for people who dose over 10 mg. But for under 10mg you can safely take it as an add on medication if you have treatment resistant depression.

In my opinion, if you aren't treatment resistant, and at the end of your ropes with constant thoughts of suicide, I wouldn't recommend taking it. There is a little euphora to it, but nothing like methamphetamine or cocaine.

I know some people take selegiline as an add on to things like adderal and ritalin also. However I don't reccomend selegiline as an add on med unless you already have a tolerance to the current drugs your taking and never go over 10mg
 
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I know some people take selegiline as an add on to things like adderal and ritalin also.
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If this is to be negotiated safely, the UTMOST care must be taken. This includes vigilance to make sure that MAO inhibition doesn't cross into MAOA, Shulgin style dosing with the stimulant to locate safe and reasonable dosage-levels (people have had unexpected hypertensive crises on as little as 2 mg d-amphetamine), careful checks on frequency of use of said stimulant to avoid psychotic mania, etc.

Basically, I haven't yet seen ANYONE exercise sufficient care with these combinations, even those with thorough pharmacological knowledge.

ebola
 
WAIITTTT.... lemme tell you something BEFORE YOU DO THAT.... i used to think that wellbutrin would have a nice stimulant effect too but guess what... now my perception is altered forever, and not in a good way, i feel tingly at night, like bugs and crawling on my skin
i can FEEL them, and see them and i get super super anxious paranoid as if they were to ever come back like that one night.... and guess what NO EUPHORIA on 3000 mg so dont try it truust me
 
ebola? said:
If this is to be negotiated safely, the UTMOST care must be taken. This includes vigilance to make sure that MAO inhibition doesn't cross into MAOA, Shulgin style dosing with the stimulant to locate safe and reasonable dosage-levels (people have had unexpected hypertensive crises on as little as 2 mg d-amphetamine), careful checks on frequency of use of said stimulant to avoid psychotic mania, etc.

Basically, I haven't yet seen ANYONE exercise sufficient care with these combinations, even those with thorough pharmacological knowledge.

ebola
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I agree, I do get sides. Sometimes I get an almost uncontrollable urge to stretch in the morning. I can resist them(like than uncontrolable feeling when you need to yawn). But when I let one go I almost stretch too hard. I don't have high blood pressure or anything. Just a weird lightheaded feeling in the morning when I get the stretch urges. It's weird.

Don't know if this is related to the antidepressants or an electrolyte balance. The pharmacist thought it was an electrolyte imbalace.. Either way I'm gonna stop taking meds for the weekend. I accidentally went against my docs directions and dosed selegiline and wellbutrin on consecutive days. Maybe I need more exercise
 
K1nGp1N said:
WAIITTTT.... lemme tell you something BEFORE YOU DO THAT.... i used to think that wellbutrin would have a nice stimulant effect too but guess what... now my perception is altered forever, and not in a good way, i feel tingly at night, like bugs and crawling on my skin
i can FEEL them, and see them and i get super super anxious paranoid as if they were to ever come back like that one night.... and guess what NO EUPHORIA on 3000 mg so dont try it truust me
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Well no shit son. You took an extremely high dose that induces delerium and seizures. Those sensations you get are probably HPP disorder and you deserve it for not researching first to know what you're doing. No one else here is stupid enough to take even close to 3000mg's. These people are trying to help their mental problems, not get fucked up and make them worse.

stupid greenlighters...
 
I am a vengeful god, and I refuse to help those who will not help themselves.

Seriously though, THAT is the RESULT of making stupid decisions. It doesn't matter if you deserve it or not, that's what happens.

You are the only one who can take care of yourself- if you want to have fun and get high, you sure as fuck better know what you're doing or you may not like the next 40-50 years in a coma.
 
ebola? said:
Does he? That is a rather harsh punishment for ignorance. I guess that your god is a vengeful god. ;)
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Only in the Old Testament. The New Testament God starts to be more forgiving and loving :)

I think he meant 300mg and not 3000mg. 3000mg would almost definately be seizure zone for wellbutrin.

If it was 3000mg, wow. I myself can't even handle 300mg, lol.
 
ebola? said:
Does he? That is a rather harsh punishment for ignorance. I guess that your god is a vengeful god. ;)
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Then he shouldn't recieve the consequences of his actions like the rest of the universe? Is HPPD really that harsh? I'd pick HPPD any day over being a vegetable. Even animals are smart enough to know not to eat psychoactive plants at higher amounts for risk of decreased survivability or death.
 
i guess my statement was a bit harsh. but just because selegiline is dopaminergic doesnt mean it produces a "buzz"

I just dont want users feeling disappointed if they are really get their hopes up about trying this like I did.

I would still take it again but only because I have a need for it, not because of some kind of a recreational reason.

I've only taken 100 x 5mg of the stuff, maybe I am being premature in passing judgement.

Rasagiline will be more interesting I hope.
 
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Then he shouldn't recieve the consequences of his actions like the rest of the universe? Is HPPD really that harsh? I'd pick HPPD any day over being a vegetable. Even animals are smart enough to know not to eat psychoactive plants at higher amounts for risk of decreased survivability or death.
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Okay. We're confusing ethical responsibility, prudent management of one's own actions, and reliable causal patterns. :) Moot point though.
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I had good experiences on selegiline. It's subtle, though, and after a couple of months, I stopped really noticing it. No withdrawal with cessation, of course.

ebola
 
permastoned said:
^ Prove it please? Do you realise that I am quite a large guy, and it has always taken large amounts of substances to affect me compared to other people.

Some people have much higher levels of MAO than others, this has been shown in many studies.

Furthermore, the studies about the selectivity of selegiline for MAO B were all done in the elderly.
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Feel free to take whatever doses you think are best for you, but DO NOT give others advice according to YOUR dosage scheme.

5mg is an AVERAGE dose of selegiline. 15mg is 3X the average.

This is a Harm Reduction message board, and what you're doing is NOT harm reduction.
 
Jam, you are saying that as somebody who has not taken the stuff im assuming.

The day I finished them off I think I ate 7 in the space of just a few short hours (= 35mg).

5mg is the lowest dosage, not the average (oral not transdermal or injected).

entirely unrelated, but benzylamine is a pressor amine also metabolized by Maoi-B, perhaps this could be taken in a manner similar to what is being done with PEA?
 
rocknroll714 said:
I said what I said not because of the fact that he's simply my friend, but due to him being my friend, I've been acquainted with him long enough and well enough to know that he's not a "troll" and that he does indeed merit a degree of respect. I'm simply suggesting you give him that respect because I feel he deserves it. That's all.
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LOL Maybe you ARE him, with another username that you only use for posting your half-baked idea's while stoned to protect your reputation. Just admit it! You're not fooling anyone! HAHA!
 
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