Yesterday upped my dose to 2.5mg after getting what i deemed were insufficient effects despite eating with a small but fat-laden meal.
Got extremely tense after adding modafinil, which I tend to snort at low doses to titrate my "level" just right. Added a small glass of japanese sake and a bit of cannabis and had an awful time - tense and itchy and just feeling unwell, somehow "not right" and my mind going in circles and thinking unbeneficial obsessive thoughts.
I must say that a few days before I had had a tiny bit of modafinil and no selegiline on that day and I got some stimulation that allowed my to beat my all-time tetris against-the-clock high-score, which i thought was ace... borderline jittery for an hour or so but acceptable. On the whole I would say, though, that combining selegiliine and modafinil is contraindicated.
Elsewhere on the forum I read that others have found the combo of cannabis with selegiline a bit uncanny as well... and alcohol is a no-no according to the manufacturer's factsheet, though I do not fully understand the reason why this should be so.
Oone thing I did today because of my perceived lack of effects from selegiline alone on the previous days was to take my 2.5mg under the tongue (half a 5mg pill) - bitter and numbing, but ok - as it is said to increase bioavailability by a lot... 10 times, was it, nano?
And today I got none of the speedy restless body efffects I got the first couple days I took this drug (once or twice then also under the tongue). Seems my system is getting used to it and it is becoming comfortable.
Only things I want to watch out for is possible tolerance developing or accumulating too much MAO inhibition in the medium/long term (hence breaks may be advisable as has been said before) and getting adequate sleep. Seems the drug keeps me awake for absolutely ages, somehow. That is something I need to keep under control because I feel a slight risk of this pushing me back into hypomanic territory (during those phases I usually get by on very little sleep for weeks on end, only to crash majorly later and feel despondent and tired all the time for weeks as well... MUST avoid this!!) In any case today for the first time in a long time I felt pretty much "just right" and I started putting my life in order (having recently moved and switched continents and all), starting to work on my studies again finally after a 4-month abstinence that felt like a neverending road to ever-elusive recovery, me thinking "wtf is wrong with me" ever so often... and I found myself enjoying the task and being able to stick with it and being able to concentrate for hours on end... GREAT! As I said before, makes me wonder how "old" my brain would look to a neurologist looking at the state of certain neurotransmitter levels / neurons / synapses /whatchamacallthem... I suppose 4 years of SSRIs and many more of weekend poly-drug use including a few iffy combos including much MDMA&h when in my early 20s prior to taking SSRIs for depression and while taking SSRIs take their toll...
Anyway for now selegiline really feels like a godsend to me. My feelings of tension and despondency are greatly reduced, I feel as good as I haven't for months, and at the same time my cravings for beer and for K have pretty much gone. K seems Ok in combination with selegiline but I have no longer got such a strong desire for it as i feel less need to disconnect from emotionally unpleasant experiences... as they no longer seem so. And I had been getting worried that i was getting quite hooked on K as my top-up&go anti-depressant/anaesthetic and had been getting worried about running out...
Can't believe I'd never tried selegiline before. I'd known about it for years but always avoided it precisely because of the potential issues withe MAO inhibition. But I think that that is precisely what makes it so good. I got my first taste of what MAO inhibition feels like when i first took Ayahuasca... oh the aftermath, thank you!! Quite different from just DMT, so much more comforting. And they say true Ayahuasca wiill always contain some MAO-inhibiting plant... it may or may not contain a DMT-containing one... I understand now. For me, the MAO inhibition is what makes DMT bearable... unless already well and truly inebriated annd peaced out by various other mind-pacifying agents. But that's me, YMMV, of course.
Seems to me deprenyl has pro-sexual effects as well indeed, although not more so than, say L-arginine. Seems to delay ejaculation slightly, which is a side-effect i welcome.
What I like the most is how it seems to set me "right" and how it reduces most of not all my cravings for other things, all my vain attempts to self-medicate... if the price to pay is nnot being able to take 2C's etc then so be it. I will almost certainly experiment with one of the 4-substituted tryptamines at some point affter I have managed to maintain my balance on this godsend as they are easy to dose, come on quickly and wear off quickly too. But I will start extremely low. Would like to try AMT at some point as well but I have a hunch that may not be super-safe with selegiline as it lasts so long and has quite a body load on its own and as it may have some MAO activity. How long would I have to stay off the selegiline before being able to ingest a full dose of AMT safely?
Long post... i don't post much on BL any more as my interest in drugs purely for entertainmment has waned majorly over the last years but I felt like sharing this and would be pleased to read of anyone's experiences with l-deprenyl, alone or in combination. Any advice as to my questions and speculations is also welcome.
Thanks for reading, and a happy new year to all. Stay safe.
