hugo24
Bluelighter
- Joined
- Mar 23, 2005
- Messages
- 867
There are still those trying do synthesize selective 5-HT2 agonists,heres one for the C receptor (isn't that the anxiogenic?).Don't know what to do with it but at least the molecule looks good
BiLZOR?
I also heard of another pharmaceutical company active here,searching for a anti-obesity drug.2C-B was also tested
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"Synthesis and biological evaluation of novel hexahydro-pyrido{3',2':4,5}pyrrolo{1,2-alpha}pyrazines as potent and selective 5-HT2C receptor agonists A novel series of chiral ... has been discovered.Several analogs had low potential to induce phospholipidosis in vitro and showed low affinity for the hERG potassium channel."

I also heard of another pharmaceutical company active here,searching for a anti-obesity drug.2C-B was also tested

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"Synthesis and biological evaluation of novel hexahydro-pyrido{3',2':4,5}pyrrolo{1,2-alpha}pyrazines as potent and selective 5-HT2C receptor agonists A novel series of chiral ... has been discovered.Several analogs had low potential to induce phospholipidosis in vitro and showed low affinity for the hERG potassium channel."