I've done Yopo seeds, they were bloody intense, I crushed them in a mortar and mixed them with baking soda(didn't have any lime powder), then snorted. It was visually very strong, didn't last too long but it was fun. It was back when I was really into Aya brewing, mushroom growing and the lot.
I actually did two types of those seeds, forgot the latin name, one was adananthera peregrina or something similar, the other ones were different. One of the two types made me more sick, I puked on both but one type had a sort of poisoned feeling that lasted a few hours.
Both had an amazing afterglow though, strong mood lift for the rest of the day.