The second time I dosed with 2C-E it was intramuscular, at 7-8 mg. I already had some tolerance having tripped on 2C-E 1st time insufflated at around 25mg (I was dead set on a balls-to the wall-experience first time and got it) then about 10 mg of 2C-I a couple days later. I felt I underdosed at this point, but I attribute that to tolerance to some degree from my frequency. Two days later, I got tired of screwing around and getting dosed less than what I wanted and hit 21 mg of 2C-I in my thigh - vastus lateralus. It was a hellishly beautiful experience!...and I would gladly do it again at the same dose, but not a mg more without an anti-convulsant on hand. Don't think I would need at 22mg IM, but why take chances? I did this at about 9:30am knowing I had a wedding to be at 6pm. I was not driving lol. At this dose with 2C-I, I started losing it and was a little scared, but the fact that I had to get ready for a wedding in a few hours helped keep me focused...well, on something. That kinda helped me keep track of who I was. I was borderlining on ego-loss and for 2-3 minutes right when I was reaching my peak, I forgot I had taken a drug....wow! Mods, please excuse, I know the OP was interested in 2C-E, but due to the lack of info in general on IM with 2C-X in general, I still though this would be helpful. I would NOT apply this info to any of the other 2C's (serious, serious...please don't underestimate)because of variances in potency and the high dose/repsonse curve with most of them. However, with 2C-E and 2C-I, I would be okay at the same level in the right setting. I honestly could not tell you if having a goal for the day helped me keep my shit together, or was making me nearly lose it. I guess it might be fair to say i was bouncing between. I am going to try an 18 mg IM dose of 2C-E this weekend at a party and see how it goes. It's Halloween and a bunch of drunk people present (may make things difficult) are really going to push me (I'm going to be ANNIHILATED!), but I KNOW what i'm getting into. I plan to be almost done with my peak (dosing a couple hours before dark.)by the time things get too wild at the party. Not AT ALL recommended for first timers, I can't stress that enough. I'm in my mid-30's and had plenty experience with psychedelics and keeping my shit together under stress. I personally think 5-7mg IM is a pussy dose IM, but then you can't say what is right for someone else based on one person. Who knows? I might produce more MAO than you do, and that may be why 5-7mg sucks for me. I say start experimenting at 5mg and go up from there. There is a big diff between E & I so I'm dropping it down for 2C-E. 2C-E IMO is major-league shit. (although beautiful major league shit LOL). I'm pushing myself to the limit to learn something, not to have fun, per say, and I will have people watching me, and have MY appropriate meds on-hand to stop my trip in case of unforseen shit happening. Based on my experience, I would recommend to the OP that 8-18 mg is a tripping hard to balls-to the-wall range, and probably too high for beginners. If you have had a high dose before and are okay with it, go for it, just be careful and have fun.
If anyone is interested in a trip report or has questions, please let me know. I'm not an authority, but I will give you a well thought out answer and a well informed point of view at the very least.
This is my first post, so thanks to the mods and all of you that have contributed. You have all taught me quite a bit.
Edit: Error in my own post, sorry. MAO shouldn't really have anything to do with IM injection so please ignore that part.