DMT has caused some quite varied reactions for me.
1st time I tried it it was awesome, no spine sensation I can remember, I laid back and got a lot of closed eye visuals that were awesome.
2nd time I tried it it started out scary because I got a really really huge hit and everyone around me looked really fleshy and bony but then I came down and took a few more hits and relaxed every muscle in my body and it was really really soothing.
3rd time It was great because I got the hang of "exercising the surrender muscle" and relaxing every muscle in my body and had some really entertaining trips with my friends while watching Tim & Eric and then shortly afterwards right before playing a mario party minigame lol
4th time and 5th and 6th times were really small hits that I got from letting people use my pipe and stuff (mainly just a really nice body high/relaxation and mild closed eye visual stimuli)
7th time I did it (by this time I was really good at lighting it) I got like probably a little over 20 mg in one hit and I had this really odd sensation. I laid down and was listening to music, but all I could hear was the fan in my room. The sound of the fan got really over powering and it felt like energies were being sucked out of me by the fan. The previous day I tripped really hard on 25 mg of Metocin, or 4-ho-MET and I had a hard time for a little bit because I thought that the world was ending or I was getting closer and closer to 'nonbeing.' Pretty much the day before I had a paranoid hour or two that left me with a bit of a negative vibe, but when I smoked the DMT it seemed like anything bad that might have happened to my brain chemistry got reversed by the DMT or something.
In stead of that trip having the typical red glow that I always see it was a bright blue green, which was the main color of the CEVs of the Metocin from the day before. When I got up I noticed everything looked slightly different, and I felt a lot more sober than I did before I smoked the DMT.
Since then I have been taking a short break from DMT.
I still haven't broken through. When I do I plan to listen to this
http://www.youtube.com/watch?v=U7JQgyNw068
I have gotten pretty damn good at using my base pipe and plan to smoke upwards of 50 mg in one hit if my lungs will let me.