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  • BDD Moderators: Keif’ Richards

Roxicodone Inactive Ingredient question

Pjkt2501

Pjkt2501

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Dec 5, 2011
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Hi, I've found this: http://www.bluelight.ru/vb/threads/534538-Inactive-Ingredients-A-to-Z however the information on different brands of Roxycodone isn't present.

I'm mainly interested in the KVKtech brand (k 9 imprint, blue) 30mg pills, as these seem to cause a negative reaction in my girlfriend (I have no issues w/ them in this fashion, however I do think them to be inferior to an A 215, M 30 [or M 0552], or V 48 12). This leads me to believe that the issue is in the filler / binder / dye, and I'm curious as to whether there's a known difference in makeup.

Physically, the k 9 imprinted ones are in-between the "waxy-ness" (texture when crushing) of the A215 (more powdery) and V 48 12 (much more "waxy").

If anyone has some insight I would appreciate it, thank you.
 
What type of negative reaction? If she's allergic to something in the pill, I'd be quite surprised as I've never heard of such a thing happening, but I guess it is possible. I guess that sucks for her. however, could this effect because by something else? I've had less enjoyable or almost non-enjoyable opiate experiences at dosages that I've enjoyed many times before. Anxiety, nausea, stomach content and pH, etc. can influence how the drug responds during a isolated experience. I'm not trying to discount your story, just throwing out ideas.

How are they inferior? If you don't have the negative reaction there could only be a minimal difference in effects from that specific 30 and another generic. The binders/fillers can slightly alter the rate of absorption, but that wouldn't change the Cmax, or Tmax in really any significant way. The FDA has protocols in place to make sure the same level of efficiency is seen for all generics produced. Also being that your gf had an negative reaction, this could easily play into why you may perceive they are inferior.

I've been given a 2mg hydromorphone IV shot before, and was given the same dosage for the couple previous days, yet that one particular time due to the state of mind I was in (a little manic, anxious, general mental state being off from normal), made that 2mg shot not noticeable at all. I honestly thought the nurse didn't even give me the dose. I was wrong, and he actually did. So don't discount the mind from influencing your opinion of the particular generic.

Please don't take this the wrong way, just throwing legitimate possibilities out there
 
(I'm not taking any of it wrong, it's all constructive mate, and appreciated. :) )

Nausea and dizziness, mainly (her reactions). Doses have been insufflated (I understand all about the BAs and such :p), and while I understand the drip results in an effectively oral ROA, I've taught her proper technique to keep it in the nasal cavity.

In terms of inferiority - I'm 95% sure it's just placebo to be frank. They always break up in a weird way, and never "feel" the same as an A215 does, or M (either type listed). V's are hit or miss as they have a coagulant that reacts to water, so insufflating them w/ a runny nose makes it a bloody ER med - gotta hock them lugies (yeah, gross) to keep getting a dose. Isn't all THAT bad when it comes to it haha. I'm with ya there bud, just a preference I figured I'd throw out there for sake of completeness.

She's been under some stress lately due to school and $$ (her work isn't open during February, so she's out like a grand + of income - she's 20), but she isn't NOT feeling the dose, it's just these particular pills give her the aforementioned side effects, but as also noted, an A215, taken in the same mental state, doesn't.

I agree, strange indeed and I feel psychosomatic, but the exact same thing happened yesterday (though she was already in a crummy mood due to the weather). She doesn't have this reaction to 5/500 oxycodone/APAP either. (Yep, I too am scratching my head.)

Well, thanks for your input, I do appreciate it as it's at least something to go by. (And yeah, sucks for her and I. She's gonna take some more, feel like crap and yadda yadda, where she could just use her 5/500's and not, but whatever. I wanna CWE the 5/500 and evap the solution, re-CWE it, evap and see what my yeild is, but now I'm digressing quite far haha).

The make up of the 5-6 different types of oxycodone are all rather different in terms of consistency while crushing and once crushed. (That I get - I don't often have a choice as to what it is due to not getting them via Rx (yet)).
 
Roxicodone (there is no such thing as 'Roxycodone') is a trademarked brand name for rapid (where the R comes from) release preperations containing oxycodone produced by a company called Xanodyne (previously Roxane). Their pills are scored with the number "54" followed by 3 digits depending on strength and can be white, green, or blue also depending on strength.

The pills you listed are not Roxicodone but generic oxycodone preperations produced by different companies.

K9=KVKtech
A215=Activis
M30=Mallinckrodt
M0552=Mallinckrodt
V4812=Qualitest

They are all instant release and have the same active ingredient (oxycodone) though in differing amounts depending on the dosage. The information on their inactive ingredients (binders, fillers, and dyes) can probably be found online via each company's websites or at the FDA's if you are in the U.S.
 
Thank you for the nomenclature clarification. The "Roxycodone" was a typo - as the title as the correct spelling (inconsistency, and I'm worn a bit thin currently, apologies).

Had the KVKtech website even acknowledged that they mfg oxycodone hydrochloride, I may have had better luck prior to making this thread.

http://www.kvktech.com/?s=oxycodone

Thank you for the FDA suggestion. I'll poke around there next.

http://www.accessdata.fda.gov/scrip...rch.Overview&DrugName=OXYCODONE HYDROCHLORIDE

This has no listing for a KVKtech manufactured oxycodone hcl pill.

Other suggestions where to look? I'm all ears. Even if it doesn't answer my gf's issue, I'm now quite curious as to why these pills in particular aren't showing up anywhere...
 
I can't figure out what's going on with KVK-Tech either. Maybe they have a different sub-name for the production company making them or something. Probably best to just send an email off to the company asking for information.

This link will be helpful for all the rest though and K9 might be hiding in there somewhere as well.
http://www.accessdata.fda.gov/scripts/cder/ob/docs/tempai.cfm
 
:\ That website doesn't list inactive ingredients. Ahh well.

I guess an email to the company would be best at this point. I'll wait a bit to see if anyone else has an idea.

Thank you for your help though.
 
The A 215s are the best ones. They are 33% active ingredient. weighing 90 mgs total, with 30 mgs of oxy in them. next come the mallinckrodt ones, weighing 120 mgs, (making them 25% active ingredient.
 
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