• Neuroscience & Pharmacology Discussion Welcome Guest
    Posting Rules Bluelight Rules
    Recent Journal Articles Chemistry Mega-Thread
    FREE Chemistry Databases! Self-Education Guide

  • N&PD Moderators: Skorpio

Ritalin Alarm Clock

H

hamhurricane

Bluelighter
Joined
Feb 12, 2007
Messages
1,032
Location
Riding A White Swan
when i was prescribed d-amphetamine i would set my alarm an hour before i needed to wake up to take my morning dose and then go back to sleep, when the real time came to wake up i would do so with ease and alertness.

since switching to methylphenidate i find that it does not assist me in getting up at all and i can easily sleep though my dose. at later points in the day these drugs seem equivalent in stimulation. does it have to do with difference between dopamine release and dopamine reuptake inhibition? I know that levels of dopamine in the brain plummet while we sleep, could it be that with less dopamine crossing the synapse methylphenidates reuptake inhibition has little effect? or is it just a personal idiosyncrasy?
 
Personal reactions vary, and there are numerous other complex considerations (like blood-brain barrier), but methylphenidate's affinity for adrenergic stimulation is much lower than dextroamphetamine (which releases something like 5:1 norepinephrine:dopamine). A lot of people find methylphenidate sedating. Most of the consensus is that methylphenidate is more potent in blocking the dopamine reuptake pumps than the adrenergic pumps, although there are a few abstracts which disagree.

You might try adding a mild caffeine source, like yerba mate, although many people have problems with a psychostimulant/caffeine mix.
 
setting my alarm super early, dosing with LSD and then returning to sleep created one of the most disorientating, crazy, confusing and wierd experiences of waking up in my life

i know this doesnt help but i feel that its all i could add :)
 
I've considered doing that, although with the trouble I have with insomnia anyway, waking up and trying to go back to sleep on purpose seemed like asking for trouble. (Gods knows I've done it without meaning to.) Interesting to hear that it works, though.
 
Mine is vice versa, often I have taken drugs too late in the day only to sleep through the peak of the effects. Some drugs which make u drowsy and disorientated (like alcohol) are ideal to sleep on. I cant imagine doing this with a psychostimulant.
 
ifonly said:
setting my alarm super early, dosing with LSD and then returning to sleep created one of the most disorientating, crazy, confusing and wierd experiences of waking up in my life

i know this doesnt help but i feel that its all i could add :)
Click to expand...

I know what you mean, but my experience was with shrooms and later with 4-ho-Dipt.
 
Oh... I was kind of hoping that someone had devised a machine to deliver them ritalin in their sleep, so that it would kick in while they were sleeping and wake up nice and ready to go. I would so love to have one of those things, so I could actually sleep all the way up to when class starts. Hmmm... maybe I have to design one of these things... It would be so much better than that "clocky" thing that runs around your room--especially for us ADD kids whose room is usually more messy than a villiage after a tornado hits. (I swear, unless clocky had 4 wheel drive, it would fall off my bedtable and get stuck in a pile of stuff...)

I find that when I take my ritalin, I can sometimes go back to sleep, and then wake up an hour or two later ready to go. However, sometimes, I will just keep sleeping. I don't know what it depends on.

Sometimes my ritalin actually helps me sleep. I really can't figure out why it is so variable.
 
You must log in or register to reply here.
Top