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Research alcohols list

421 said:
How about isopropanol? I've heard of skid row types doing "research" by drinking isopropanol antifreeze, effects are said to be similar to ethanol at considerably lower doses.
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It metabolizes to acetone, so... bad idea. I remember staysedated did a report on it somewhere on here. He said it was a bit more potent than ethanol, but he had the worst hangover.

Most of the ones I listed are oxidized and glucoronidated so there are no toxic metabolites.
 
DL-ark said:
They may not have any toxic metabolites but im fairly certain most of them, if not all are pretty inherently toxic.
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Perhaps but ethanol is inherently toxic too and has toxic metabolites (like acetone), which is why I didn't have an issue recommending isopropanol as a replacement. The good part about ethanol is the millenia of human research done on it so we have a pretty good idea how toxic it is.
 
421 said:
Perhaps but ethanol is inherently toxic too and has toxic metabolites (like acetone), which is why I didn't have an issue recommending isopropanol as a replacement. The good part about ethanol is the millenia of human research done on it so we have a pretty good idea how toxic it is.
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Which is why people should stay away from alcohols as a whole, they are toxic, non-selective, and have low affinity and low potency per mg.
 
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