• Neuroscience & Pharmacology Discussion Welcome Guest
    Posting Rules Bluelight Rules
    Recent Journal Articles Chemistry Mega-Thread
    FREE Chemistry Databases! Self-Education Guide

  • N&PD Moderators: Skorpio

Repairing fried nerve endings

This question cannot be answered. Try heavy and consistent anaerobic exercise. What you are describing cannot be quantified......
 
Stop taking drugs. Eat healthily. Get regular exercise.

SSRIs have been shown to increase neurogensis in the hippocampus.. and saint johns wort (well the chemical in it.. hypercium or something?) has been shown to upregulate 5-ht receptors.

If you use SSRI's.. only use them for a month or 2.. Then imo the beneficial effects are complete..

Oh.. thread is 5 years old ^^
 
Neurogenesis is a sort of "catch-word" on forums such as this, and is not always good. For example, glioblastoma multiforme promotes tapid neurogenesis, and the outcome is not good.
 
^neurogenesis is also a legitimate and important term in embryology, gerontology and malacology (the study of molluscs)
 
MobiusDick here has stated that upon heavy MDMA usage, he no longer retained the eidetic memory that he once had. I have heard similar anecdotes elsewhere. Also with methamphetamine. They don't call these drugs neurotoxic for no reason.
 
If you damage a nerve in your hand, arm or even your neck it grows back, albeit slowly. If you damage a nerve in your Central Nervous System it doesn't grow back because of the environment it's in.
 
BilZ0r said:
My opinion: Stuff like that ^ is a waste of your money and time. I mean, shit, if you want to eat fish oil/OMEGA-3 then do, it's good for you, it's not going to harm you, though it's pretty expensive, but it's not magic cure for brain damage.

But all this piracetam etc stuff, I don't trust it as far as I can throw it... people mix up euphoric effects and pro-cognitive effects when their judging results subjectively.

I think treating your problems, whether they are a result of MDMA or not, is a good idea. I don't know if some citalopram or bupropion will help you with your depression or anxiety.

I do know that I find it unlikely, unless you were heavily abusing MDMA, that you have true axonal loss.

How long have you been abstinant for?
Click to expand...

I don't mean to pry, but could you define "heavily abusing"?

Aswell, does 11 times (1-2 pills max) in a period of 16 weeks, redosed once ( 1 pill then 1 later), and never using more than once a week, sometime once every 2-3 weeks, qualify or fit that definition?

I'm quite convinced I've suffered some serotogenic axonal loss, mainly after my last use where ALL these symptoms started occurring, but my pdoc tends to disagree as I experienced a traumatic event whilst on E. This lead to flashbacks for months, depression, anxiety and loss of cognitive function. Clearly my pdoc diagnosed me with PTSD, but it's extremely hard to differentiate, considering I'm the equation.
 
Uhg MDMA is such a tricky subject and there is a lot of information that keeps being discredited. Someone says nerve endings in the brain do regenerate, another person says it doesn't. Someone brings up how axons should be reconnecting and re sprouting within 1 month, and some say that wont be at a substantial level until about the half year mark. Its just such a depressing subject because of how oddly and strongly the chemical works on the sensitive serotonin system. I was reading some pubmed journal entry and i think it was saying generally after a respectable average usage of mdma, the serotonin axon terminals should be firing in normal patterns and cycles by around the year mark. Now there are a lot of other factors and i forgot what the usage was like in that journal, it was very complex information. But those supplements sure would help, even if a lot of it is placebo that is better than nothing. Omega 3 fish oil, and B complex vitamins should really help with the process of neuro-transmitters being replenished.
 
Look up Iboga/Ibogaine. I'm pretty sure it's been shown to promote nerve growth/neurogenesis. And ibogaine is converted into noribogaine, which acts as an SSRI.
 
Reefer Madness.. "Just one marijuana cigarette... .. Isn't enough!!"

"...Chronic, but not acute, cannabinoid treatment promoted neurogenesis in the hippocampal dentate gyrus of adult rats and exerted anxiolytic- and antidepressant-like effects. X-irradiation of the hippocampus blocked both the neurogenic and behavioral effects of chronic cannabinoid treatment, suggesting that chronic cannabinoid treatment produces anxiolytic- and antidepressant-like effects likely via promotion of hippocampal neurogenesis..."

http://www.jci.org/articles/view/25509
 
You must log in or register to reply here.
Top