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Opioids Relapsed on oxy aftsr 5 years clean. Whem can I restart my Subs

RobustTuna

RobustTuna

Bluelighter
Joined
Jul 28, 2025
Messages
55
Location
USA
Long story short I fell off the wagon big time about 3 weeks ago. Been using oxys daily (40-160mg) and I want my old sober life back. Been Kicking the s*** out of myself mentally 24/7 for the past 2 to 3 weeks. I have a great life, great job, great family and I want to handle this before. It's too late. I had just celebrated 5 years clean.

Here's my question: How long do I have to stop taking opiates to begin takimg my subs again. I have heard if you just start retaking them it can throw you into precipitated withdrawals. Can someone please offer so guidance as I know where this road leads if I keep using oxy/other opiates.
 
RobustTuna said:
Long story short I fell off the wagon big time about 3 weeks ago. Been using oxys daily (40-160mg) and I want my old sober life back. Been Kicking the s*** out of myself mentally 24/7 for the past 2 to 3 weeks. I have a great life, great job, great family and I want to handle this before. It's too late. I had just celebrated 5 years clean.

Here's my question: How long do I have to stop taking opiates to begin takimg my subs again. I have heard if you just start retaking them it can throw you into precipitated withdrawals. Can someone please offer so guidance as I know where this road leads if I keep using oxy/other opiates.
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Mate I only speak as a heroin smoker - was told 12 hours between last smoke and first bupe dose. I advise waiting until you are rattling - doesn't have to be full withdrawal, it just has to be in the post (runny nose, watery eyes, restless). Trust me - you DO NOT want to take bupe too early, it is days and sometimes longer of full blown withdrawal.
 
There is no set time frame. Going by hours is a sure fire way to pain. Like the other poster said, seriously wait until you start experiencing proper withdrawal. Oxy is forgiving when it comes to this.

Also, there’s a new medically accepted method for treating precipitated withdrawal. Ironically, it’s dosing MORE buprenorphine. I can tell you from experience, it does work and macro-induction is far more successful than micro-induction (Bernese method).

Due to this fact, whenever I re-inducted, I started dosing with 16mg off the bat. Held under the tongue for 15 minutes to ensure proper absorption. Said goodbye to the Bernese method forever. Have had zero problems since.
 
Helpmeescapethis said:
There is no set time frame. Going by hours is a sure fire way to pain. Like the other poster said, seriously wait until you start experiencing proper withdrawal. Oxy is forgiving when it comes to this.

Also, there’s a new medically accepted method for treating precipitated withdrawal. Ironically, it’s dosing MORE buprenorphine. I can tell you from experience, it does work and macro-induction is far more successful than micro-induction (Bernese method).

Due to this fact, whenever I re-inducted, I started dosing with 16mg off the bat. Held under the tongue for 15 minutes to ensure proper absorption. Said goodbye to the Bernese method forever. Have had zero problems since.
Click to expand...
I find this quite interesting - I always thought there must be a way to treat it, there has to be.

Funnily enough - I am on a 16mg dose of bupe yet when I smoke gear I still get fucked up, dunno if it is the market being flooded with nitazenes?
 
justme6263 said:
I find this quite interesting - I always thought there must be a way to treat it, there has to be.

Funnily enough - I am on a 16mg dose of bupe yet when I smoke gear I still get fucked up, dunno if it is the market being flooded with nitazenes?
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There is plenty of reasonable evidence via anecdote to suggest that the Zenes are able to displace the Bupe on the receptor and allow someone to then get high even if they have been on stable replacement for yonks.

And sadly it seems most gear is now just mystery powder with Zenes.

Far as I’m aware 8-24mg of Bupe is your bread and butter “blocking dose” but with how potent Zenes are this now may be not applicable anymore, but I’m not sure myself, no idea about bindings etc so this is just speculation.
 
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RobustTuna said:
i just want to thank everyone for all the helpful insight. This is a great community of people!
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No worries - it is a brilliant community, I've been given no end invaluable advice and surely been saved a hospital visit or two...
 
justme6263 said:
I find this quite interesting - I always thought there must be a way to treat it, there has to be.

Funnily enough - I am on a 16mg dose of bupe yet when I smoke gear I still get fucked up, dunno if it is the market being flooded with nitazenes?
Click to expand...
As a near daily user of pure nitazenes, and daily user of bupe, I can attest that they easily break through bupe.

Even it is is regular heroin, loads of people don’t allow for optimal absorption of their bupe, only holding it in the mouth for 5 minutes at most. Which always let me easily break through, years ago.

There are so many variables when it comes to buprenorphine and concurrent opioid use.
 
Helpmeescapethis said:
There is no set time frame. Going by hours is a sure fire way to pain. Like the other poster said, seriously wait until you start experiencing proper withdrawal. Oxy is forgiving when it comes to this.

Also, there’s a new medically accepted method for treating precipitated withdrawal. Ironically, it’s dosing MORE buprenorphine. I can tell you from experience, it does work and macro-induction is far more successful than micro-induction (Bernese method).

Due to this fact, whenever I re-inducted, I started dosing with 16mg off the bat. Held under the tongue for 15 minutes to ensure proper absorption. Said goodbye to the Bernese method forever. Have had zero problems since.
Click to expand...
So itts enough to rip the oxy off but still not give you precip? I’m wondering about this regarding my situation which is tapering from 20mg of oxy a day
Doc gave me 20mcg/hr patches and said that should work too like Bernese method… what do we think? Last time I took .3mg sub a few weeks back I was high as a kite and these patches give ~.48mg per day. Could that be my Bernese method?
 
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