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Redosing 2C-E

LiveIllegal

Bluelighter
Joined
Oct 25, 2005
Messages
2,094
A friend of mine acquired 2C-E recently, and tripped on it three different times. The first time It was a dose of 10 mg, which had noticeable but minimal effects. The next two times were 15 mg and then 18 mg. This friend is assuming he has a higher tolerance to this drug than most people because while most report 18 mg being very intense, he had strong visual and auditory distortions, but by no means was the trip intense. It was stronger than 15 mg and a little longer, but the effects were basically the same.

This friend has acquired some more 2C-E from the same source, and plans to up the dose to 20 mg. However, if the results are not satisfying, he would rather just redose at the appropriate time rather than wait a few days and take a higher dose, using up more of the batch. My question is this: how long should he wait before he decides he needs to redose, without waiting too long for it to be effective? He typically begins to feel the come-up after an hour, and peaks after 2 to 2.5 hours.

Is this even a good idea, or should he just wait and try again at an even higher dose?
 
This is purely conjecture, but if at the 2 hour mark after 20mg of 2C-E orally, he's still not experiencing what others can achieve at lower doses, then possibly the best way to add a bit more would be to administer say 5mg rectally. This would be equivalent to say 10mg orally, but because of the faster onset via the rectal route, might not suffer the sort of tolerance issues that 5HT2a agonist drugs seem to be prone to. The tolerance from the initial dose would also most probably reduce any unsettling effects that can occur with rectal dosing of the 2C-x psychedelics.

Alternatively, instead of 20mg orally, he could go with 10-12.5mg (dissolved in water for admin with a syringe) rectally in the first place. This will be a faster, more intense ride up, but if 15mg has been doing very little for him, it might just do the trick.

If he decides on that route, make sure he understands that rectal 2C-E is about 2x the potency of the oral route as the effects of 20mg rectally could turn into a bout of 'welcome to my nightmare'.

Remember, in all things - SAFETY FIRST
 
I have attempted boosting with 2C-I around the 1.5 hour mark (25mg initially w/ 5mg boost) and it seemed to only increase the duration of the trip, rather then the intensity. I'm not sure how this would play out with 2C-E, but it is the only info I have right now. Given that the peak can take 2.5 - 3 hours to achieve, it might be a bit risky since I have heard of the peak effects ramping up pretty quickly in a short amount of time.

The only psychedelic I have ingested where boosting seemed to increase the intensity of the trip was 5-MEO-AMT, which also takes 3 hours to achieve peak effects. The boost was taken two hours after the initial ingestion (6mg then 4mg for a boost) and I experienced no extra body load, only a stronger mental mind-flagging. I'm not sure how this would carry over to 2C-E since it is a phenethylamine and 5-MEO-AMT is a tryptamine but I imagine the results might be similar.

With whatever he does, just be safe and remember how quickly the peak effects can ramp up once they do phase in.

Good luck %)
 
In general I find redosing psychedelics is very sensitive to the timing. If you redose too late, as in like after the peak, some tolerance due to the first dose will likely have set in, weakening your second dose. Also, by the time the second dose kicks in, much of the first dose will be worn off. OTOH, if you redose too soon, as in like before the peak, then you might underestimate the intensity of the original dose, resulting in more than what you bargained for. Put simply, with a substance that has a come up time of 2-3 hours, its very hard to titrate a dose by redosing in real time. As someone suggested, you could try the rectal route, which should have a faster come up time, but you are still going to be essentially chasing a moving target.

My recommendation (if I made recommendations - I don't) would be that your friend just go ahead and try just doing a single dose of 22mg and see if that works. I know 2c-e has a steep dose/response curve, but since your friend has tried 15mg and 18mg he should be ok with 22mg. The 4mg increase isn't going to kill him, and at worst it might just blow him away, which is what it sounds like your friend is looking for.

Now if the 22mg dose is lacking in intensity, then he could wait a week and try yet a higher dose. However at some point if it continues not to work your friend might be best off realizing that 2c-e was not meant for him.
 
Ok, thanks for the responses. Is it possible that his method of consumption has something to do with it? He mixes it in a glass of orange juice and drinks that.
 
My body gets pretty upset with 2ce and if I take more than 18mg at a time I just get sick within about 15-20 min. of the capsul breaking. So I dose in two small doses of say 15mg and 8mg seperated by about 40 min. It's worked well so far as I get the increased trip of the bump and my stomach doesn't get too upset. I wouldn't wait too long to decide to redose if he does but I don't see it being a problem.
 
It's been said but not quite enough IMO: it is important to dose earlier rather than later with these compounds. I would definitely suggest boosting well before the peak, the best results for me are found when I repose as I feel initial come up effects, somewhere in the 45 min to 1 hour range (on empty stomach).

And of course, be careful. Don't be heroic with 2c's. If you take them for granted they will give you a psychedelic kick to the head so hard your grandchildren will be retarded. Work up the dose curve gradually, thats all I got to tell you.

Happy tripping!
 
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