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[Rectify]

2-methyl-3-phenyl-pyrrolidine
opsin.ch.cam.ac.uk

SUPERMAN

 

[Smyth2]

2-methyl-3-phenyl-pyrrolidine
opsin.ch.cam.ac.uk

SUPERMAN

See example 94 in this patent: https://patents.google.com/patent/US8642642

 

[4DQSAR]

2-methyl-3-phenyl-pyrrolidine?

Do you mean 1-(1-phenylpropan-2-yl)pyrrolidine?

MDPPP turned up in Europe a couple of decades ago.

But as MDPV was more potent but more toxic than pyrovalerone, in this case I imagine that a para methyl would increase activity. Prolintane was the milder parent compound to pyrovalerone, so I would assume that to be the case here.

As it is, yeah, I suppose it would be active. Just not very active. It's one of those cases in which chiral synthesis really would be of benefit. I guess it to be oh, about 1/10th the potency of amphetamine, the addition of a p-Me would double that, but still not so potent. But likey safe and I would guess legal.

 

[Smyth2]

If you see Ex 94, you can see that the compound is made from Boc-(2S,4S)-4-phenyl-pyrrolidine-2-carboxylic acid [96314-29-3].

This precursor is commercially available since it is used in the synthesis of Fosinopril.

https://www.chemdrug.com/article/8/3285/16420062.html

Would the SS isomer give the desired product though?

 

[4DQSAR]

Good to see you digging into those precursors.

 

[Rectify]

 

[Rectify]

AMP

 

[Rectify]

NEXT_GEN_WELL_BUTRIN
N-tert-butyl-1-(3-chlorophenyl)-1-carbomethoxy-2-aminopropane

Don't Expect Much, Just Not Quite Enough.

From Bupropion Via The Andersen Sequence.

 

[Rectify]

Many People Have Always Thought I Am Dumb, So I Transferred To Augusta Prep In 10th Grade And Decided To Get High On Information.

These Are My Test Results:

Salutatorian
STAR Student

SAT
750 Verbal (of 800)
800 Math

Achievement Tests (of 800)
720 Biology
720 Spanish
720 English
680 US History
790 Math Level 2
680 Physics

AP Exams (of 5)
4 English
4 US History
5 Calculus AB
5 Physics AB

Several Years (And Much Partying) Later

MCAT (of 15)
Reading Comprehension 13
Biological Sciences. 9
Physical Sciences 11
Writing: R

 

[Rectify]

"In Xanadu, Did Kubla Khan A Stately Pleasure Dome Decree." - Samuel Taylor Coleridge.

 

[Rectify]

Brahma Is Shiva's Higher Power.
Vishnu Is Brahma's Higher Power.
Shiva Is Vishnu's Higher Power.

It's A Cycle!

"Perfecto Bien, Andres!" - Ann Catena

 

[Rectify]

Eugenol --> 3,4-dihydroxy-1-allyl-benzene --> Safrole.

It's Not Brain Science.
It's Science For Brains.

 

[kiely]

 

[Rectify]

This Is Probably Available As An MDxx Precursor.

Eugenol + B(Br3), boron tribromide

 

[Rectify]

Okay, here's my 0.02 USD (2 cents) for today.

SPIDER_MAN
1-(2-(methylthio)-3,4-dibromophenyl)-2-methylaminopropane

MEGAN (the primary amine, dichloro version) was Gr8 When Combined With AMP.

 

[Rectify]

Alternatively,

YETI
1-(3,4-dichloro-2-methoxyphenyl)-2-methylaminopropane

If you wanna turn down Spider Man's intensity a couple of notches.

 

[Smyth2]

Alternatively,

YETI
1-(3,4-dichloro-2-methoxyphenyl)-2-methylaminopropane

If you wanna turn down Spider Man's intensity a couple of notches.

3,4-Dichloroamphetamine still strikes me as one of the agents I would want to try. However, idk about the reputation that it causes brain damage. There are other similar agents though like Cericlamine, 2-Amino-6,7-dichlorotetralin, 5,6-Dichloro-2-aminotetralin [57915-89-6] & 2-Amino-5,6-Dichloroindane.

I had some decent theoretical improvements on how to make 2-amino-6,7-dichlorotetralin but I haven't looked at the files in years now.

 

[Rectify]

3,4-dichloro-amp needs amphetamine with it to reach its full potential. N-methyl-3,4-dichloro-amp on the other hand has tons of push without needing to combine it with another stim. The difference one methyl group has in this case is quite remarkable.

 

[Allylbenzene]

roi posted about this and explicitly specifies the chemical name.
I've not found much on it except dose/ROA/duration guidelines and roi's post. It's listed on pubchem here.

2-methyl-1-phenyl-3-(piperidin-1-yl)propan-1-one
...
Summary: Substance dissolved incredible easy in water. 50mg rectal seems to be a nice recreational dose, however too euphoric to get work done. Not much of a body high though, seems to be rather mental, no crazy amounts of energy, feels really clean. Comedown is not unpleasant at all, not much of a urge to redose. Short duration (2-3 hours), but pretty enjoyable.

So yeah, if you go the oral route it'll probably take around 100mg. Decent stim, nothing to rave about though.

Never tried unsubstituted methcathinone, sorry.

And this is NOT a cathinone, nitrogen moved one further down.

It's also reminiscent of these safrole metabolites:

 

[Smyth2]

I checked my database in muscle relaxants and have two folders one for propiophenone Mannich and one for acetophenone Mannich.

The propiophenone Mannich yielded the following list of agents:

1. AD-2239 HCl: [90852-27-0]
2. Eperisone
3. Inaperisone
4. Lanperisone
5. Perisone Fb: [22385-99-5] HCl: [6281-80-7].
6. Silperisone
7. Tolperisone

Your agent is Perisone in the above list and is a muscle relaxant not a psychostimulant.

[1] SUMITA, Kazuharu; KOUMORI, Masayuki; OHNO, Sachio (1994). "A Modified Mannich Reaction Using 1.3-Dioxolane". CHEMICAL & PHARMACEUTICAL BULLETIN. 42 (8): 1676–1678. doi:10.1248/cpb.42.1676.
[2] Eiichi Morita & Takeo Kanai, US3995047 & US4181803 (1980 to Eisai Co Ltd).