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"Rebuilding" the brain

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somedud

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I have a question and figures this would be the spot for the most knowledgeable answer. Post MDMA abuse, I've started 10 mg lexapro (SSRI) and was wondering if this could help regenerate/aid the production of new cells/axons in the hippocampus, or for this type of situation would it better to go the natural method and stick it out for the best long term solution?

I'm currently thinking of quitting lexapro and going on SJW, which upregulates as well as sensitizes the 5HT1A and 5HT2A receptors.. I'm also taking quite a list of herbs and Nootropics to help with the repair.

What's your thoughts on the SSRI use ? I don't want to be "rewired" into a emotionally flat zombie, but would like the best route for the optimal serotogenic repair.

Cheer guys, help and options would be wonderful. :)
 
SSRI's are useless and mostly placebo. When they aren't, the entire point of the drug is to blunt your emotions so therapy can help.

Detox off of SSRIs for a week or two and switch to SJW. Also pay attention to habits, sleep, lifestyle, and diet. Those four go a long way.

Nothing can rebuild your brain once you've destroyed it. You only get one :P
 
Thanks, I've been routining a good exercise diet and trying to break thought patterns. Sleep is hard to conduct, after last useage insomnia struck in and stuck around since, 7 months post.

I only consumed 20-30 pills in like 3 1/2 - 4 months, never doubling dosing or rolling twice in a row, once a weekend at max, seems strange how such destruction happened.
 
I would guess you aren't actually experiencing damage from MDMA, as per your description. MDMA is a relatively safe chemical, its very unlikely to elicit problematic damages with they type of use you have suggested. However, pressed pills are notorious for containing other not so safe chemicals and drugs.

I would say do exactly like Seiko said, be safe with your body and be confident that your doing what you can to live well.

ANW
 
I agree and disagree to some extent, with out neglecting your time and kindness in responding. I had alot of negative factors at the time of my "abuse", break up, concussion, drop out of school.

I believe the amount of CNS stimulants I was using for the gym then mixing with high dosage of alcohol and pressed pills was the exponential out bringing of my symptoms. I forgot to mentioned I used for 3 years or so, but very sparingly and took a 5 month break before starting that binge due to school and never noticed a single side, maybe anxiety.

What leads me to believe it's what's occurring is for one the declaring of depression after my last few uses, then after suffering a concussion, using again, which to me seemed to restrict the blood flow of antioxidants to certain regeins of the brain causing very poor removal of the toxic metabolites of MDMA and scavenging of the free radicals. The direct cognitive problems, panic attacks and brain zaps which persisted for months lead me to believe neurotoxicity, even though it could be attributed somewhere else.

Seeing how low dose SSRIs greatly lifted my mood at start gives me hope, showing there's something left. But still have the typical symptoms of MDMA abuse, or "etards". If your either bit interested read one of my posts currently active in ED and give me your thoughts.

At this point everyones input is a godsend to me, the "dark side" is an unappealing place.
 
^^ the OP wants to upregulate 5HT receptors, which ecstasy/ssri's downregulate. im assuming you've been in ED, havent you seen all the threads/talk about how piracetam helps people "regain the magic"? so me thinks the piracetam helps upregulate and/or sensitize 5HT receptors.

i think. :)
 
how much mdma were you abusing? should be the first question everyone asks...

then we could respond with, if the damage is difficult to prove, and most of the methods above suggested for new neuronal growth are dubious at best.

what symptoms are you even getting? excercise, improving diet and having a job and social activities do help to keep you on a wellbeing track.

last week i did 0.7-0.8g of mdma on the saturday night, then about 1g again on monday night/tues morn. i dont feel brain damaged (wether i feel it or not is really heresay), but being busy, eating well, help so at the most all i have is a mild case of the sniffles. have been taking 5htp on comedown day and the odd zopiclone here and there.
 
im on paroxitine..have been for over 10 years..due to being a pill head in my younger days i suffered with massive panic attacks anxitey and basicly ruined my life but after 2 months on the meds my life started to improve dramaticly and was back on top form with in a year , im only on 20mg ed and would deffo say im far from a mindless zombie (un less i put myself in that state lol)and live a good life, tbh if i didnt get my head sorted id have probably topped myself it was getting that bad
 
Not a whole lot really, before this last binge I'd use very sparingly, around .5 to 1 pills occasionally, (no not .5 g to 1 g of Molly, .5 - 1 pills), then took a good 4-5 month break or more, no symptoms, aced my uni semester. Probably rolled between 30-40 times in around 4 years. Anywhom, then started rolling apps once a weekend for about 3 1/2 -4 Months, no more than 3 pills a night max, total of about 20-30 pills. But was also taking with high amounts of alchohol and stimulants for the gym earlier in the day. Also mixed with dancing and on certian rolls fucking for about 3 hours, so alot of overheating.

Anyways symptoms such as memory loss, personality loss, depression, crazy insomnia, anxiety , panic attacks and depersonalization..

7 months post, DP still here a bit, anxiety still here, insomnia and depession as well as cognitive issues. Finding it hard to relate/connect with people on many levels and I don't naturally understand people like I use to, or social cues forthsg matter anymore which is the WORST part, as if I have aspergers or some shit..

Anywhom, that's your list of symptoms.
 
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sekio said:
SSRI's are useless and mostly placebo. When they aren't, the entire point of the drug is to blunt your emotions so therapy can help.

Detox off of SSRIs for a week or two and switch to SJW. Also pay attention to habits, sleep, lifestyle, and diet. Those four go a long way.

Nothing can rebuild your brain once you've destroyed it. You only get one :P
Click to expand...

Prove it.

SSRI's have shown to induce neurogenesis in the hippocampus.. this is one theory as to how they work as it starts (or atleast gets to a significant phase) at around 3 weeks from begining treatment.

I found SJW pretty useless to be honest.. but bear in mind i can't recall what my drug usage was like around the time of taking it..

By the way your brain (/you) will most likely get better with time.. an SSRI might actually hinder recovery time..
 
the best anti depressant i ever took (and i took it after a few weeks of mdma binging) was tramadol, once daily in the morning.

far superior to ssri's. i never needed to up my dose either. coming off them was weird and a bit uncomfortable but knowhere near the empty cold horror of coming out of the citalopram bubble.
 
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See I don't want to avoid my current depression , I want to solve it for the long run, mainly my mental capabilities so I can get back to school, I have a feeling staying away from AD's is the way I should go and naturally let the brain do it's thing.
 
probably, though since the tramadol i have never needed another anti depressant. it did something very good that i dont need to repeat
 
No pharmys for me. Think SJW would help or hinder, stuck on this one. Has pharmaceutical properties, with the label of a herb. The upregulation is the only thing I'm considering it for.
 
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