Reationship of Disphoria and Euproia, NMDA Antagonists, & Cessation of Drug Use

[Jabberwocky]

I have been taking a high dose of Piracetam for some time now and DXM for a short time now. I am also a recovering heroin addict, who recently used DXM to withdrawal from the dope. Aside from noticing antisocial behaviors decrease since beginning the Piracetam and DXM combo, which is significant in and of itself, I'm also interested in something else: Nicotine and NMDA antagonists.

I've cut down on smoking since stopping the heroin, simultaneous with stopping it really. On the one hand, nicotine feels like it did when I first started smoking five years ago. It totally fucks me up, if for only 45 seconds. But then, once the buzz is gone, I also notice all the negative side effects of smoking, such as inability to taste or smell, phlegm, coughing, etc. etc. much stronger than ever before.

In short,

• Do you think the tolerance reducing aspects of the NMDA antagonists I'm taking have lowered my tolerance so much that, although I find the buzz much stronger, they have also reduced my tolerance (from cognitive, behavioral and biological standpoints) to the negative side effects of smoking?

For the first time, I am actually aware of and notice the negative side effects of smoking (as previously noted, manifested overal as a kind of overall dysphoria). For the first time I can distinguish them from the positive effects of smoking (i.e. the buzz/euphoria).

The same thing seems to have happened with the opiates, but I'm to scared about going back to them to test this ATM

Thanks in advance!

 

[basement_shaman]

Are you aware that the racetam drug family can be used to almost completely cancel out the dissociation from drugs like DXM, ketamine and MXE? It pretty much just leaves you with the SNRI and sigma effects (DXM) or the dopaminergic effects (ketamine/MXE). Are you using the combo specifically for this purpose?

 

[Jabberwocky]

No I was not! You just answered a totally different question. Thanks a lot!!!

 

[skillet]

Just a quick point - codeine, and presumably heroin too, is an antitussive, which could explain the increased coughing now you've quit. Maybe the phlegm is also more noticeable now because of that?

 

[Jabberwocky]

Yes, that is true. Didn't think of that. Thanks skillet!

@basement_shaman: Will the NMDA antagonist action of DXM, if I use it at a consistent dose, eventually lower my tolerance to DXM's dissociative effects, assuming my dose of Piracetam also does not change? I am beginning to think that is why I had a certain powerfully psychedelic experience yesterday.

 

[negrogesic]

Just a quick point - codeine, and presumably heroin too, is an antitussive, which could explain the increased coughing now you've quit. Maybe the phlegm is also more noticeable now because of that?

Assuming that the individual is past the acute-moderate phases of withdrawal, I doubt that past heroin abuse could explain 'increased coughing' in this case.

What exactly is your question here......

 

[Jabberwocky]

Never mind. Thread can be closed. Thanks.

 

[skillet]

Assuming that the individual is past the acute-moderate phases of withdrawal, I doubt that past heroin abuse could explain 'increased coughing' in this case.

What exactly is your question here......

I didn't mean like a rebound thing, just that maybe those things were hidden to some extent while TPD was using.

 

[Jabberwocky]

I have a sneaking suspicion this was the case, as I am not past the post acute stage of w/d yet. That being said, I have been taking a lot of Guaifenesin recently too. Like, a lot. Who knows. I'm just happy not to be craving cigs right now. Yippee!!!

@Skillet: would you suggest I look into SNRI meds with a health professional? If so, do you have an recommendations? Just for personal info, curiosity, and research purposes. Thanks for all your help here!