• BASIC DRUG
    DISCUSSION
    Welcome to Bluelight!
    Posting Rules Bluelight Rules
    Benzo Chart Opioids Chart
    Drug Terms Need Help??
    Drugs 101 Brain & Addiction
    Tired of your habit? Struggling to cope?
    Want to regain control or get sober?
    Visit our Recovery Support Forums

Re withdrawal from tramadol?

B

bpayne

Bluelighter
Joined
Aug 26, 2008
Messages
1,549
Re withdrawal from tramadol? UPDATED

I had stopped tramadol and all other opiate use for a while.. well last monday I received 120 tramadol.. I took them all during the last week. running out last night.. exactly one week later.. I was addicted for tramadol for a while but haven't used it in over 2 months.. do u think I will experience withdrawals from this Week of productivity? as the Tramadol has not cleared my system yet I'm sure it is a bit nerve racking wondering if I should reach for the loperamide ahead of time.. or maybe it won't be very bad as It was only a week.. yet due to the amount that I went through(yes I know it's a lot.. no lectures on that please, it's actually a bit less than my usual dosing regimen) I have a feeling that a week might just have been enough to kickstart the sickness.. I dunno. what do u guys think?
 
Last edited:
bpayne. I honestly dont know.. Everyones bodies are different. I know with me I got ill after just a
4 days on a tram bingette..But only 2 days of that insomnia. lot of restlessness and emotional rollercoatering... then a few days later I felt sickly for a day. Ive had opiate addictions before though and I think ive read somewhere that this could have made my mu receptors or whatever (lol) more sensitive*
I think if you havnt had any signs of withdrawal by the morning youll probs be ok :)

I wish I could say something more positive.. Try to think positive about it and get hold of some
diazepam maybe or a sleeping pill or two in case you do go into withdrawal.


*sorry I dont have a source but i'm sure if anyone is interested its googlable.
 
I don't think you'll experience anything too serious. Minor WDs at worst. Have you withdrawn from tramadol specifically before? If not, there are signs you have to look for, and some of the usual opioid signs will be missing as tramadol is atypical to say the least. If anything at all, you'll experience very minor physical symptoms since tramadol's opioid effects are quite mild (nothing like the flu-like symptoms of typical opioid WDs) which may lead you to feel the whole WD will be easy, but look out for artificial depression. The first time I experienced tramadol withdrawal (300 mg/day for 4-6 months, nothing too heavy), I didn't note any serious physical symptoms and didn't realize the severe depression I was experiencing was being caused by the withdrawal until I'd been coping with it for about a week. I still had another week, week and a half to go before the artificial depression finally subsided. Tramadol's primary effect, at least for me, is its mood-lifting, anxiolytic, socially enhancing effects (the lesser opioid effect comes ~90 minutes in with the M1 metabolite), and these are the benefits you will probably be lacking most in withdrawal.

Just something to look out for, but I don't think this will be a difficult cessation for you.
 
yeah I've withdrawn from up to 2000 mg a day over a year or more from tramadol. I've withdrawn from it probably 10-15 times total in the past.. the withdrawals for me are always Worse physically than normal opiate withdrawals such buprenorphine and hydrocodone.. , I hadn't had any in the last 2 months since my previous withdrawal period so 2 months off.. then A week on a very large dose daily.. so I'll just have to see if the symptoms return

and also like you ayrios I use tramadol for it's SNRI effects on serotonin and norepinephrine more than it's M1 effects.. but it's M1 effects are what Always make me sick in the end.... I never really get depressed during tramadol withdrawal. just physically sick as shit.. usually If I find other opiates it makes the Sickness go away very easily.. but I use it for energy lift and mood enhancement.. it allows me to get a lot of work done and be very productive with a clear focused mind.. and also allows me to quit all other drugs such as alcohol.. marijuana, stimulants.. ect.. and just be a productive person.. but in the end that damn M1 is the main cause of my punishment at the end of such a binge.. tolerance escelates very rapidly for me.. as I had gotten up to 20 50 mg pills a day in the past.. and that was about what I was averaging just the day before yesterday and finally yesterday when I ran out.. I neglected the idea of a taper cause because of the thinking that since I've only been back on it a week that to draw it out further might actually cause the symptoms I'm trying to avoid.. I suppose only time will tell.
 
Last edited:
I know how easy it is for tramadol mgs to escalate.. and it looks like youve either seen that you were taking to much or been given the opportunity to see that. Im not going to preach mate ive done it myself.. 1000mg of Tram is an overdose though and you having been making
yourself really vunerable to siezures etc.

Did you get twitchy?

Let us know how it goes wont you .
 
bpayne said:
yeah I've withdrawn from up to 2000 mg a day over a year or more from tramadol. I've withdrawn from it probably 10-15 times total in the past.. the withdrawals for me are always Worse physically than normal opiate withdrawals such buprenorphine and hydrocodone.. , I hadn't had any in the last 2 months since my previous withdrawal period so 2 months off.. then A week on a very large dose daily.. so I'll just have to see if the symptoms return

and also like you ayrios I use tramadol for it's SNRI effects on serotonin and norepinephrine more than it's M1 effects.. but it's M1 effects are what Always make me sick in the end.... I never really get depressed during tramadol withdrawal. just physically sick as shit.. usually If I find other opiates it makes the Sickness go away very easily.. but I use it for energy lift and mood enhancement.. it allows me to get a lot of work done and be very productive with a clear focused mind.. and also allows me to quit all other drugs such as alcohol.. marijuana, stimulants.. ect.. and just be a productive person.. but in the end that damn M1 is the main cause of my punishment at the end of such a binge.. tolerance escelates very rapidly for me.. as I had gotten up to 20 50 mg pills a day in the past.. and that was about what I was averaging just the day before yesterday and finally yesterday when I ran out.. I neglected the idea of a taper cause because of the thinking that since I've only been back on it a week that to draw it out further might actually cause the symptoms I'm trying to avoid.. I suppose only time will tell.
Click to expand...

Ahh ok, then you're much more experienced than me with tramadol WDs ;) At that daily dose M1 must have really been tough, no doubt overshadowing any emotional issues... Sounds like a withdrawal to rival methadone or poppy pods. Regarding those quick SNRI effects--I think if doctors were willing to prescribe "spot treatment" anti-depressants (use it when you're feeling a bit depressed or angsty only, not every day), tramadol would be at the top of the list. I suppose I can see the abuse potential if tramadol were marketed to people in that way, though... It can brighten any day, so why not always take it? :P
 
haha yeah.. I dunno if the m1 is quite that strong.. dunno. I know that I feel nothing off of large doses of codeine except an end to my restless legs.. and it takes upwards of 20 mg of oxycodone just to not be sick when coming off of tramadol so I guess that is near the range of potency would be my best guess.. anyways I'm not sick yet.. maybe a little sweating but I haven't had the ac on yet today. just have to see.. and yeah to yellow.. I never really get twitchy from tramadol.. I notice that I am generally a bit twitchy and shaky anyways for whatever reason and high doses of tramadol usually steady that right out dunno why.. I am aware of the seizure risk.. and Use to be very careful about it. .then I noticed that no matter how high I went I never had a seizure.. even taking it every day.. I suppose I've just been lucky.. don't want to push my luck too far I suppose..
well I'll just have to wait and see what later tonight or the morning brings
 
Well IDK but I don't think your gonna have to much of a withdrawal, and dang after using tramadol for 8 or more years I still don't have the guts to take more than I am sposed to. My max is/was 9 per day. In anycase when I get my oxycodone script I always just stop taking it cold turkey and don't have any issues. Hopefully it goes ok
 
Okay well last night withdrawal set in pretty bad.. I haven't gotten any sleep at this point 2 pm the next day.. so yeah even a week back on.. it hits ya.. the bad part is I am suppose to be going out of town tomorrow for a mini vacation to the mountains with my Girlfriend our daughter and her Family .. who has no idea I do anything other than smoke cigarretes drink beer and Blaze a lil sum sum.. I was gagging and throwing up this morning.. Theres no way I can be seen in this Condition... so I went out and got me some withdrawal supplies... a bottle of cheratussin ac codeine syrup, an economy size box of 96 2mg loperamide tablets.. a quarter ounce of Kali Mist Dank.. and a couple cases of Beer... Hope this will be enough.. oh I also have a few bottles of dextromethorpan cough syrup if the going gets really tough.. think I'll be set?
 
Well, those things should help! I'm not an expert in this though.. if you want to get some more support (not to say you aren't getting good support here, but TDS is great for emotional support and speaking to people going through similar things - we've got a few threads there with people currently detoxing) then feel free to start a thread in The Dark Side (link in my sig) - or take a look at the opioid dependence/withdrawal megathread.

Good luck <3
 
DXM is an excellent substitute for tramadol. do NOT take them together though; only take DXM on the days you don't have tramadol.

both dextromethorphan and tramadol affect extracellular serotonin and norepinephrin levels, and bothare NMDA-blockers. even though tramadol (and its main metabolite) binds tighter to mu-receptors, DXM is a potent sigma-1 receptor agonist making it an effective, legal (OTC in most countries), and cheap substitute. DXO is a powerful NMDA-antagonist aswell...

adder said:
Note that many opioids also act on sigma receptors. This even led scientists to put these receptors into the group of opioid receptors. E.g. morphine is a sigma agonist but its affinity there is very low so this property doesn't play much of a role in the general action. Also, many opioids are also NMDA channel blockers. NMDA channel and sigma receptors happen to be in the same regions of human brain thus many NMDA blockers also act on sigma receptors. So it wouldn't be much of a surprise if there was found some evidence that opioid receptors, sigma receptors, and NMDA channel are all so close that substances acting strong on one have some impact on others, be it strong or light. But that's just theorizing. A good example of an opioid that acts on mu, kappa, and delta opioid receptors, and also activates sigma receptors and blocks NMDA channel is levorphanol, besides it's a weak SNRI; thanks to all these properties levorphanol is effective against a wider range of types of pains than morphine.
Click to expand...
 
Last edited:
so yeah even a week back on.. it hits ya..
Click to expand...

in high doses, yeah, it'll do that to you. it's a pretty common phenomenon between opioid users who have been dependent and withdrawn many times; dependence seems to creep in that bit quicker.

tramadol is especially harsh to come off cold turkey in my personal experience. the combined withdrawal SNRI and opioid properties make it much different withdrawal to full agonists.
 
DXM ( about a bottle) gave me a bit of peace from TRam withdrawal.. I was able to lay on the sofa and watch tv instead of the awful restlessness that dm withdrawal manifested for me. Have a coco for when you come down incase you get a headache.
 
How are you BPayne :) <3 sending you gentle breezes to your head.. sweet thinking and stamping down paranoia etc.. peace n love and just think your
body is getting stronger every minute every hour.. its its job!!

blessings xx
 
So from what I am trying to understand since I am coming off cold turkey, its day 4 from a 7 year 15 pills of tramadol a day. So what kind of Loperimide do you take to help? I also have a bottle of wellbutrin i saw someone mention it might help. Diphenhydramine just makes the restless legs even worse. I have no access to any benzo's cuz i not longer have a doctor or insurance. All your ideas and gonna save me im hoping. THanks everyone.
 
Canyou get hold of a tens machine or those electric muscle stimulating pads that everyone has lying around... they apparently help with the RS.
Meditation is a potent weapon .. keep getting into the now.. empty your mind of what ifs.. or why did he/she and stay here and now in your room.watch a echart tolle video or find some other zen videos that will take you through meds.. maybe they will be the cool breeze for your mind today.
Remember it will pass.. you are fighting a mighty hard battle but at the end the crushed and exhausted you will be the slayer!!! RRRAWR

Maybe a dxm will help but dont take it with the diphenhydramine,
 
Last edited:
I do have a tens unit and a broken installed spinal cord stimulator. I am not throwing up, but I mostly cant stand the restless legs and the TENS unit doesnt help. Been taking all I have which is Robaxin, Goodys, and Diphenhydramine. i guess i could drink some DXM but here's my problem. I have had a gastric bypass and its hard to get a 4oz bottle down. I also have Wellabutrin but I am scared of seizures, same with the diphenhydramine.

I live in southern Alabama, so I know we dont have that nice Robo AC syrup OTC here. I guess I could drink but I am extremely broke. Oh i HATE this, I wanna give up, it feels like it will never end.
 
No dont have the dxm with diphenhydramine. Read through the descriptions on erowyd etc..
doesnt look pleasant. I'm not familiar with the other drugsyou mention..

check out the interactions here http://www.drugs.com/drug_interactions.html

It will end though sweetheart promise. :)

Youre a mighty warrior!!

Praying for you luv and you bpayne let us know how you are doing :)
 
Last edited:
Hey sup everyone.. I got back from the Mountains Yesterday... First couple of days were fairly rough. but a tiny bit of codeine syrup and a fioricet pill in the morning and about 6 beers at night helps me get to sleep.. First night even with all that I slept maybe 3 hours.. Second Night same routine and slept about 4-5 hours third night.. no codeine.. just lost's of Loperamide and beer and weed.. helped immensely.. 4th day had to walk through Tweetsie railroad in the 30 degree snow all day.. but coffee and loperamide and a bit o the chron chron pushed me through it.. 5th day came back. slept fine with a bit of beer.. Last night I slept a full 9 hours or so and have extremely minimal restless leg going on.. it's almost gone though at this point.. I'm debating whether or not to even take the Loperamide today.. I didn't even take the Dxm as I wasn't sure if it would make me act Bizarre or not in front of my girlfriends Family lol.. Luckily the other men of the family Drink a lot so me drinking all night was never a problem.. Man withdrawal sucks.. I always usually just drink and smoke my way to sleep during the nights.. This cannot be good for the body though and Don't recommend it as a treatment.. the whole up and down Rollercoaster of it all has to have a traumatic effect on my physical health.. .. all in all I ended up having a decent time out in the Mountains.. also being around so many other people actually made me kinda push my own physical problems to the side and Deal with it in a less whiny more productive manner..
now..

Mystical Gateways Damn man How are u holding up? First of all Never ever ever ever ever take Benadryl when your withdrawing it makes your rls even worse.. the Dxm may work for you but make sure that what your taking is Only Dextromethorphan.. u say you just recently had a Gastric Bypass? that sounds like a lot of stress on your body already dude if it's any at all possible I recommend tapering your tramadol dosage I always try to before I run out.. Take Hot Hot Hot baths to help alleviate the Legs for a Few Minutes, and try to use a Heating pad on your Legs when your laying or sitting on the couch or bed. also Loperamide DOES help..Loperamide is an opiate but it doesn't cross the blood brain barrier meaning it doesn't cause any central effects.. but since it binds to receptors in the gut it will help for some of the symptoms like RLS.. .I have been using about 14 mg of Loperamide every morning.. and it doesn't make me Mentally feel any better at all but it does cut the RLS into almost Nothing.. just barely there.. you may also want to look into Kratom... I try to always keep some Kratom around... I didn't have any this time but usually Kratom kills all of the withdrawal for me.. but then it has it's own withdrawal syndrome so u have to be careful with that one... I need to take my daughter out trick or treating tonight and I will probably be just using the loperamide and a fioricet(only butalbital no codeine) no drinking tonight.. anyways I hope you feel better.. the symptoms should get lighter and lighter each day out.. but some of them do still linger for quite a while.. .I suppose this is "Paws"... anyways sorry it took me so long to get back to ya'll but I was dead Tired last night after getting back.. anything else you'd like to know.. I'm happy to discuss with you
Stay Strong Mystical! Soon you will out of the woods of the first portion.. and then the mental boredom of just not being where you want to be and the annoying but not debilitating version of the physical effects will be all that's left !
B
 
You must log in or register to reply here.
Top