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Heroin Question regarding insufflation - (powder vs liquid)

Twiztidd

Greenlighter
Joined
Dec 14, 2012
Messages
17
I have a rather odd question regarding the difference between insufflated powder vs liquid. When insufflating powder, more often than not it is too easy for some of the powder to go right past the nasal cavities, and right into the throat/lungs, which I'd imagine can be an uncomfortable, and I'm sure unhealthy thing to happen. In an attempt to prevent this from happening, my friend mixed the bag with water as if to shoot it, but instead put that liquid into a nasal spray bottle and attempted to use it that way.

However what he noticed is that when using it in this form, for some reason it seems to make him sick. Headache, Nausea, and just all around uncomfortable feeling. This occurs with just one bag mixed, and starts happening before he even gets halfway through it. However in the powder form, he can do 2 bags plus and be completely fine.

What would be different when it's in liquid form as opposed to the powder form that could account for this? Any ideas?
 
depending on the dryness of his sinuses. he may be getting horrible bioavailability with powder. using the water could be making its BA significantly higher.
 
Maybe he's causing a cutting agent to absorb more rapidly that normally wouldn't but if you're talking about opiates it's probably like what serotonin101 said, he's getting a stronger dose.
 
It sounds like he's making his doses more effectively absorbed; headache nausea etc are the typical symptoms of a mild opioid overdose.

It's really unlikely that a "cutting agent" is starting to take effect only after dissolved in water.
 
depending on the dryness of his sinuses. he may be getting horrible bioavailability with powder. using the water could be making its BA significantly higher.

That is exactly what I was thinking at first too, and normally I would've just chalked it up to this, and not even bothered to ask the question here. However he has an EXTREMELY high opiate tolerance. I mean, 80mg oxycodone orally, and 20mg opana insufflated together only gets him slightly high for a little less than an hour. So this is why I thought it might be something other than the actual H causing it. I also forgot to mention that another side effect he experienced when doing the liquid was severe chest pains.

He has very little experience when it comes to actual H though... His tolerance was 100% built on pharms. Is there that much of a difference between H and pharms that could account for it? Or could it really be some kind of cutting agent that somehow gets activated or stronger when mixed with the water?
 
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