question for opiate gurus

[diche]

i have pentazocine and morphine. should i combine? are/will there be any possible interactions. of coarse they are two very different opitaes and pentazocine is a kappa (agonist?)

id just like some commentary
thanks.

maybee this belongs in BD but i thought i d post it here

 

[negrogesic]

Do you have a tolerance...

 

[biggerstronger]

pentazocine is an mu antagonist or partial antagonist. What's your reasoning in combining the two? Reduce tolerance?

 

['medicine cabinet']

If you have a tolerance you most likely will not enjoy the pentazocine. Sell it to someone who is opiate naive and buy more of the morphine.

If you are addicted and combine the two im pretty sure it can precipitate WD since the pentazocine is a partial mu agonist.

 

[Ham-milton]

If I remember correctly, you've been using the pentazocine for a while, correct?

If that's the case you don't have to worry about insta-WD, and while at low enough doses pentazocine and morphine will work together, when the pentazocine get's high enough, even a partial agonist behaves as a competitive antagonist in an agonists presense.

 

[diche]

thanks guys!