TDS question about loperimide

Fatjosh

Bluelighter
Joined
May 15, 2012
Messages
176
Location
california
hey guys, i have been fighting to get clean for months now. i keep getting past the physical part of withdrawl but once im there its seems like i get hit with somthing that sets me off and i fall apart.people talk about triggers but i really dont feel like i have a lot its just my coping mechanism and fucked up shit keeps happening befor i can fully get on my feet. i have not given up tho, im still fighting every day and i dont plan to give up. my question is that when i am detoxing i have been using lope once a day at night and a lot of diphenhydramine to get a little sleep. i have utfse but i hear conflicting reports as to whether or not lope sets back your recovery so i guess i would just like some first hand accounts of whether it has set you back or not. most of the reports iv read are people who just use it to get by till their next script. thanks everyone
 
AFAIK there's no solid peer-reviewed research, it's all just internet hearsay.

Having said that if you think 2/4mg of loperamide is going to help you sleep when detoxing I would do it in a second. Given it can't cross the BBB without being forced through by taking silly amounts likke 40mg I would say the value of the sleep is likely to be of far more value to you that however far it might set you back.
 
I have used loperamide quite a bit during withdrawals in the past. I find that it can eventually produce its own sort of withdrawal, not like opiate withdrawals but crumminess and restlessness. I did NOT find that it dragged out withdrawal of your primary opiate if you use it just when needed and stop when it becomes bearable again without it. I also find that you need a pretty solid dose, much higher than 2mg or 4mg. I'd start with 20mg, and if it doesn't work try 5 more until it does. Be aware it takes hours to really work so don't jump the gun. I don't find that taking so much really increases its constipating properties, but I did take to taking a stool softener when I would take it (I took it at anywhere from 60-80mg, I don't think 80 really worked any better than 60 though... and I was yo-yoing for a long time and gradually increased my dosage, I started at 40mg and it worked well. This is also how I know it eventually produces its own withdrawal). It should last a whole day so if you take it, say, 7 days in a row, and then stop, you should be good. It does help a LOT, but at 2-4mg, it will only help the stomach. You have to take more for it to do more. I don't know if this helps but I used to put them in my mouth with a little water and chew them to a thick liquid, and swish it around in my mouth for 15 minutes. Leaves a horrible taste though, I just did it because I was desperate for relief and I got it in my head it might help. No idea if it did.
 
Thanks for your replys, iv been takin 40 mg once a day as I started with 20 and had little relief and takin a stool softener too, I planned on a weeks use as I have heard of their withdrawl. I guess for reference I was taking 350 mg of oxy ir in one sitting once a day so im pleased with how much it has helped its almost too good to be true which is why I asked the question in the first place.
 
Loperamide does clear the BB barrier, it is just pumped out very quickly once it reaches the other side. When they coated it with a common food emulsifier it acted as a full opiate agonist with properties similar to morphine is I remember correctly.

It can keep alive an already existent opait physical dependency. It seems to be much easier for people to taper than the drugs that cause euphoria as the carrot is removed from the equation.

It also seems to work particularly well for people with small short time dependencies.

For those with hard and long habits it can also do very good things, but it will by no means be a free out.. at the very least a taper will be needed. If you jumped comfortably from that large dose, without much of a withdrawal, then I would taper on down or expect decent withdrawals.
 
Yeah it really takes a lot of it away, doesn't it? I was shocked when I found out, I quit successfully with it once but it only lasted a few weeks. After that it was just in my arsenal for whenever I was withdrawing.

By the way, I recently quit opiates for good about two months ago and I feel great. You can do it man! :) It's totally worth the pain and discomfort.
 
thanks alot man i had a year and one day sober when i relapsed when i found out my fiance of 6 years was cheating on me....and the rest is history. i know how good it feels to be sober and i want it back. last time was after 4 years of abuse and after the physical part i was good, but the mental aspect is whats killin me this time.
 
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