It's funny you posted this thread. I had a 2C-T-2 trip two nights ago which was so utterly profound and devastating that I feel it is very hard to deal with what I learned and re-learned. It is the kind of stuff I seem to need to keep learning again, and again, and again. It is my own sticking point, my personal apocalypse.
I believe you are correct in saying that some people will turn to tranquilizers or opiates to help deal with the raw shock of such a rude awakening. One of the recurring elements of my introspective trips is my battle with addiction to benzodiazepines. I was using benzodiazepines for 10 years straight (almost continous, bar afew withdrawals) until December 2010, when I quit cold-turkey. However, I have since taken a few doses in the intervening year for various reasons. I have been training myself during the 2011 year to trip hard without using benzos. As a consequence, one of the recurring themes during my difficult trips is that of my weakness and desire to take the 'easy way out'.
This of course uncovers all the reasons why I have been using benzodiazepines in the first place, and that is where the hell is. The whole thing can turn in to an endless causality loop: [guilt, shame, fear, anxiety] > [desire to use benzos] > [benzo use] > [psychedelic realization of character flaws covered up by benzo use] > [guilt, shame, fear, anxiety] : loop complete. This loop can last after the trip has ended, and that is why I believe you are correct in what you say.
I will say though, that it is also my revelations that make me want to completely be free from benzodiazepines and pharmaceuticals in general. So in that sense, psychedelics are also catalyzing within me a fight back against the entire cycle of use and live a fulfilling and healthy life, and try to evolve as a spiritual being.