Allylbenzene
Bluelighter
- Joined
- Jul 25, 2025
- Messages
- 982
So there's a supplement called Agmatine which is a popular pre/post workout drug thanks to its nitric oxide benefits.
It shares the same key properties as ketamine (@AMPA, NMDA, BDNF) and interacts with the classic psychedelic 5-HT2A receptor. Someone reported about the psychedelic potential of agmatine in this post. As an aside, agmatine also activates the sigma-1 receptor like DMT. Sigma-1 activation might increase dopamine synthesis/release which would contribute it's own psychaoactive qualities.
It shares the same key properties as ketamine (@AMPA, NMDA, BDNF) and interacts with the classic psychedelic 5-HT2A receptor. Someone reported about the psychedelic potential of agmatine in this post. As an aside, agmatine also activates the sigma-1 receptor like DMT. Sigma-1 activation might increase dopamine synthesis/release which would contribute it's own psychaoactive qualities.
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