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Psychedelic Cathinone Analogues.

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philosophicus

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4-Bromo-2,5-dimethoxy-Cathinone

Does anyone have any info on this? I have read a single newsgroup report claiming it is analogous in experience to its phenethylamine counterpart and is active at around 2mg.
 
I haven't heard anything about it, but it looks interesting. The cathinone analogue of MDMA (methylone) turned out to be a winner IMO. I'd like to try this and see how it compares to 2C-B and what qualities of it's own it has to offer. (meth)Cathinone has considerably less side effects than (meth)amphetamine (ime), and methylone has considerably less side effects than MDMA (ime). It would be great if this compound could produce psychedelic effects comparable to 2C-B with less side effects.
 
I apologize for the off topic post here. But Crimson Cloud and Red Haze are almost perfect synonymes(sp?) for each other.

Weird eh? 8(
 
I've always wondered why there isnt more info on more psychadelic cathinone analogs, it'll probly b very similar to DOB, I wonder what a piperazine analog of DOB would b like. I've seen it being sold by a legit chem supplier and if piperazine is related to amphetamine both chemicaly/effects than it may turn out to be interesting.
 
2,5-dimethoxy 4-bromoamphetamine is another way of writing 4-bromo-2,5-dimethoxy-cathinone. Cathinone is a amphetamine.

It's called DOB. It gets active at much lower doses than 2mg, in fact doses at 1mg would be fairly strong as well.

http://www.erowid.org/experiences/exp.php?ID=29755

I also have anthoer DOB trip report on this site, search Trip Report forum for "Comic Book Syndrome" for a DOB+Cannabis trip report.

peace,
Nitin
 
Amphetamine and cathinone are NOT synonymous. If one were to use the nomenclature of "phenyl-isopropyl-amine" for amphetamine, cathinone would be "phenyl-isopropanone-amine". I am attempting to provide a VERY simplified comparison, but cathinone is almost like a "ketone" version of amphetamine, with different effects and structure. Therefore, the 2,5-Dimethoxy-4-substituted cathinones are not the same as the DO* series.

However, the cathinone analogues of the DO* series I would estimate to be of a much lower potency (but START LOW, don't learn this lesson the hard way, I am simply proposing a hypothesis), and of much less pushy nature, more comparable to 2C-B in intensity and duration.
 
My bad; cathinone's would be marked by two less hydrogens and an extra double bonded oxygen.

But the a pharmacological profile would resemble amphetamine. And the function of a cath would be synonymous with that of an amphetamine. (ie releasing pre-synaptic catechol-amine(s) from storage in a neuron).

I would assume the analogs would be much like the origional.

peace,
Nitin
 
from an abstract of the article "The Characterization of Some 3,4-methylenedioxycathinone (MDCATH) Homologs" in the publication Forensic Science International by Terry Cason of the Chicago DEA office, 1997:

"In the past 35 years, a wide variety of illicit drugs have appeared in the clandestine market. Many of these compounds are based on the structure of amphetamine (1-phenyl-2-aminopropane) to which various functional or structural groups have been added. Previous modifications to the amphetamine molecule include addition of a methylenedioxy bridge to give 3,4-methyl-enedioxyamphetamine, and attchment of a b-keto oxygen to yield cathinone. A chemical synthesis integrating the salient functional/structural groups of these two classes of amphetamine analogs results in manufacture of methylenedioxycathinone (MDCATH). In each instance, N-alkylation of these analogs provides a series of homologs. Furthermore, many of these analogs/homologs meet several criteria which typically support the clandestine laboratory synthesis of novel illict drugs ('designer drugs'). The MDCATH analogs represent a potentially new series of 'designer drugs' whose chemical characteristics have not previously been reported. Appropriate selection of analytical, chemical and physical tests will enable rapid identification of these analogs by a comparative analysis using the data provided."
_________________

The article continues for 45 pages, way too lengthy to quote and I don't have a link for it, but most of it is about analytic procedures to identify these potential new compounds. The gist of this is that the DEA is fully aware of and anticipates this new class of cathinone analogs of phenethylamines which may or may not be coming your way.

Based on experience with MDMCAT [2-methylamino-1-(3,4-methylenedioxyphenyl)propan-1-one], I would expect potency of the cathinone analogs to be somewhat reduced but rewarding; but Shulgin tells us to take nothing for granted when trying to anticipate these things.
 
If anything, I would expect this compound to be closer to 2C-B than DOB (in effects), but anything here is based on pure speculation until there are some actual reports based on personal experience. Anyone have any?
 
On another message board (that is full of bees ;)), I have encountered a post where the poster managed to Brominate Metcathinone with the same proceadure used to Brominate 2C-H to yeild 2C-B. The end product was deemed 3-Bromo-Methcathinone. His Bioassay with 25-30 mg concluded a strong +++. No further details where given.
 
haven't you heard of methylone, that's not sched'd and neither are sertain amphetamines. One could be prosecuted for possesion of such things(possibly). That's y they call it the "grey market"
 
I wasn't talking about methylone, now was I?

However, cathinone and methcathinone are both schedule I, as is 2C-B... so this would be a great risk.
 
I thought you ment -in general, but yaeh there mosdef illegal, If I recall 2cb was available by mail order from sumwere in china until only a few months ago, maybe it still is. but 2ct7 still is
 
Originally posted by PeoplesMind
But the a pharmacological profile would resemble amphetamine. And the function of a cath would be synonymous with that of an amphetamine. (ie releasing pre-synaptic catechol-amine(s) from storage in a neuron).


only partially. amphetamine is norepenephrin(NE)-ergic and dopamin(DA)-ergic, while cathinone is purely DA-ergic. comparing mdma to methylone, the change in receptor affinities is enough to cause a large shift in the effects (methylone's full effects have to be drawn out in the proper setting, rather than like mdma, which is somewhat forceful, pushing its full effects on to you, or something like that..)

the pharmacological profile of 4-bromo-2,5-dimethoxy-cathinone would be similar to DOB's, yes, but the functions would most likely not be synonymous, and the effects would be different enough, i imagine, to be worth persuing, especially if methylone is any sort of indicator of how psychedelic cathinones would compare to their amphetamine counterparts.
 
tathra said:
the pharmacological profile of 4-bromo-2,5-dimethoxy-cathinone would be similar to DOB's, yes, but the functions would most likely not be synonymous, and the effects would be different enough, i imagine, to be worth persuing, especially if methylone is any sort of indicator of how psychedelic cathinones would compare to their amphetamine counterparts.
Click to expand...
My thoughts exactly.
 
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