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psilocybin & diabetes?

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ProjectMayhem1747

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May 4, 2011
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Really the title says it all. My girl friend is looking to try mushrooms with me and some friends this new years. And we were wanting to know from other diabetics if there was any side effects that may have happened. increase in blood sugar severe decrease anything of the such that may have directly occured due to the mushrooms. Or if ( which hopefully will be the case ) there was no complications and every thing ran smoothly. BTW she is a type 1
 
I am a type 1 diabetic and I've been taking psychedelics for years with no ill effect. Curiously the only inconsistent side effect I've seemed to have gotten from phenethylamines is that my blood sugar occasionally lowers a bit, but nothing too drastic.

The biggest thing is that she makes sure to check her blood sugar regularly, preferably once every half hour, once every hour minimum. It's hard to use your normal bodily indicators to gauge if your blood sugar is dropping or rising because the psychedelics give you a body high. For this reason I'd advise her not to trip without a sober sitter who is acquainted with her diabetes for quite a while until she is used to how psychedelics and confident she can manage her diabetes on her own.
 
Thank you i am me that is helpfull we have taken other psychedelics together and things have been fine i was just unaware of how high in carbs or sugar shrooms might be we planned to keep check on it and have some candy and insulin on hand should anything go wrong
 
I'm guessing the reason phenethylamines caused lowered glucose levels is due to their stimulating nature which will cause an overall increase is glucose metabolism. Mushrooms are not stimulating so I highly doubt there would be much of a fall in glucose levels. On a high dose one may run into some issues if the experience is markedly stressful as stress hormones can spike insulin and lower blood sugar.

As per the post above, keep a frequent log with your glucometer and adjust accordingly.
 
Well, I always considered that but interestingly, my heart rate on DOC was actually noticeably slower than normal and I pretty much lazed around on a couch doing nothing all day, enjoying the experience... yet I'd have to keep taking short acting sugar all 15 hours. It was a strange experience.
 
Haha awesome there's two of us. IamMe I bet I have been T1 for a longer % of my life than you. ;-) LOL anyways

I have a few things. (Now that I have written it, Mayhem you should just have her read this note I think. It is probably a lot for you to tell her by mouth.)

For starters, when a type 1 uses psychedelics like shrooms, they just need to be a little more heady about themselves. So while I know it can be hard to remember to check your blood sugar a little more often, this is usually the best idea. An experience like mushrooms, low or high dose, is going to give the mind & body some kind of excitement and this can cause blood sugar levels to drop unexpectedly.

Therefore the best thing she can do is check her blood sugar. Hopefully she has the small one touch travel size meter or carries her meter in her purse, so it can be with her all the time because as many people might know shrooms can paralyze individuals to objects such as couches or the ground for long periods of time. Also as mentioned, definitely make sure she keeps extra of her favorite light candy (e.g. fruit snacks, sour gummies, starburst) around (the purse) to have in case she does go low. This is particularly important if you're planning to go outdoors or be away from home, always bring extra (as in what she thinks she would need, plus even more)!

Sometimes I myself get kind of confused by the high drugs give me. They can at times feel like the onset of hypoglycemia. It can be tricky, especially if the drug makes you start sweating. So just make sure she understands to check her blood sugar if she thinks she is going low, odds are she probably is, but sometimes it is just the drugs doing their thing. For a first time user this can be a lot to deal with mentally, as far as keeping her mind from being paranoid about it. Like I said, the meter tells you everything. Make sure she has lots of test strips too if she is not at home, so if she wants to test every 10 minutes she can do it without having to worry about running out.

So really it is all about being prepared. Regarding food, as you may know shrooms are usually best done on an empty stomach to prevent nausea and bodyload. I fast for a few hours usually before I do psychs. I'd have her eat light the night before and day of, hopefully she is good about her eating habits already. Easily digestible foods are psychedelic's friends, of course this doesn't just go for T1s. But if this is not her normal approach, just remember to use the meter more often especially if you are out moving around, being active. Odds are if she isn't just sitting there the whole time, it is going to go low at some point.

As for high blood sugar, just tell her to be conservative with insulin dosing to get it back down. You don't want to take a huge dose of insulin on shrooms, then all of a sudden be like shit it was too much and my stomach feels pretty lousy. Then you're in a bind where you don't want to eat but have to. So just make sure she doesn't do that. If you plan on eating at the end of the trip (or even during, say something like fruit), and maybe are unsure how her stomach would react, I would suggest start eating first see if the stomach feels fine... then take the insulin once she knows she can handle what she wants to eat.
 
IamMe90 said:
For this reason I'd advise her not to trip without a sober sitter who is acquainted with her diabetes for quite a while until she is used to how psychedelics and confident she can manage her diabetes on her own.
Click to expand...

Yeah I'd only suggest a sober sitter if she is a very newly diagnosed diabetic. A newly diagnosed T1 though probably shouldn't be using psychs to begin with, until they get a handle on the disease. I think anyone with a good year or two experience should be fine without a sitter, as long as they recognize the drugs can cause blood sugar levels to go up and down and so they need to be extra careful of themselves.

Of course it doesn't hurt to have everyone around her know of her condition, but generally type 1s don't like to have the mental feeling of being baby sat because of their condition so I would say a sitter is probably a bit much considering shrooms are going to make her think... it would be best to have that be diabetes as little as possible, without forgetting to check her blood sugar of course.

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Ok I had another point regarding phenethylamines and stimulants, mostly for IamMe though.

So it can be a bit tricky with these drugs. Generally drugs that increase dopamine (or catecholamine) levels are going to cause blood sugars to raise. Catecholamines stimulate stress hormone release (like cortisol) which can further stimulate glucagon release, hence they can cause your BS to spike rather quickly.

The funny thing though is that excess stimulation in general (whether we are talking a DRI, 5HT agonist or mixed whatever) can also deplete your body of energy (glucose, lipids too even) supplies, and as such you end up with prolonged lows.

I'm not sure what the pharmacology of DOC is, a 5HT agonist I believe. So this is probably on the general stimulation side of things apart from dopamine's effects. But also remember if you're not eating much of any slow digesting food, fasting beforehand, etc combined with the stimulation - it's all a recipe for lows right?

Of course, some of these psychedelics could also have unknown effects on liver glucose metabolism- to slow it down or even turn it off entirely. Insulin sensitivity could also drop during a trip, leading to prolonged lows. There is really a ton of gray area...
 
WOW peptide i just want to say thank you very very much that was a the big chunk of info i was looking for. tbph i am not worried about her sugar dropping at all it never drops with out insulin causing a big upshoot is what i was more worried about. and she is not new to her condition she was diagnosed at age 10 she is now 22. the people involved are going to be her my best friend and his girl friend , his girl friend had a bad experince a few years back when they got doi sold as acid and refuses to take psychedelics at all any more so she will be sober and both are aware of her being a type one diabetic when she has her meter she keeps in her case a whole bottle of strips so running out is not a problem she has a vial of insulin she keeps at my house with needles it is also novolog 70/30 so it has the fast acting in it should something happen we can get it down with a quickness but doesnt sound like that will be an issue. thank you both for your info and input and taking the time to get me a quick response may the great energies of the universe be with you guys and happy tripping =) i know we will have a blast and the 3 of us eating that night will not have that to worry about
 
btw now if you google psilocybin & diabetes? this is the 1st thing jumpin so hopefully it can help others cause google didnt do shit for me
 
my friend who is type 1 said on the grand majority of his trips he's noticed a tendency for moreso stabilized blood-sugar levels. mostly LSD is what he was referencing, but i believe he was speaking of mushrooms as well.
 
Yeah mayhem like I said good help for you, but probably a lot more for her. I'd just print the text and have her read it, or let her log on. As I was eluding to, most type 1s don't like people watching over their shoulder, worrying about them, etc. because most of the time it is such a benign disease that we can hide it entirely, so I think if you just let her do the majority of the thinking it works out best in the long-run. I am very glad to help though. =)

thoughtsunthought, it is a tricky game. If you can start the experience with a stable sugar level, don't have a bunch of long-acting insulin in your system, don't eat anything and don't exert too much energy, yeah I've had some nights where things are just perfect for hours on end. But if you trip enough times, especially at places like festivals or outdoors where you are up moving around and whatnot, or are taking insulin during the trip for whatever reason... things can go south in a hurry.

Of course, for a type 1 things can always go south in a hurry so it's really not that much different. Just a different state of mind.
 
for sure, i wasn't sayin that to suggest someone diabetic should trip haphazardly, just throwin in my 2cents of info that i've come by.

safety first...! :) always be attentive to your body's needs....even if 'your body' doesn't seem like 'yours' at the time, and even if you're turning rainbow colors ;)
 
Good Idea

"If you plan on eating at the end of the trip (or even during, say something like fruit)"[/QUOTE]
 
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