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Pseudoephedrine - Daily use - Long-term problems

Inoxia

Bluelighter
Joined
Jan 2, 2010
Messages
271
Location
Dublin
Previous drug experiences include alcohol, cannabis, synthetic cannabinoids, mephedrone, cocaine, piperazines, bk-MDMA, methylphenidate, diazepam, zopiclone, dextromethorphan, diphenhydramine, and lysergamides.

Several months ago, I began using Sudafed (pseudoephedrine) tablets to deal with nasal congestion. At this time I had not consumed any drugs within at least two months, other than regularly drinking alcohol. I would generally consume one 60mg pill every morning. I soon began to notice unusual effects; a couple times I became extremely drowsy. More reliably, after consuming pseudoephedrine I would intermittently experience a very euphoric 'rushing' sensation which would make my whole body tingle. Enjoying the increased energy and rushes, I took higher doses on occasion (up to about 240mg, perhaps once or twice a week), while continuing the medicinal use.

After nearly a month of daily use, however, the experience began to change. There was one day in which I took only one 60mg pill in the morning, and that evening while sitting calmly, the skin-tingling rushing sensation hit me, but not like it had before. There was no euphoria. My entire body was tingling intensively (uncomfortably so) for at least thirty seconds, during which time I had severe tunnel vision. I thought I was going to lose consciousness, but luckily it passed. In retrospect, this seems to have been a withdrawal effect; in my defence, neither the pharmacist nor the manufacturer warned against long-term use.

Unfazed by this experience, I continued using pseudoephedrine as usual, perhaps 120mg per day on average.

A few days later, I again took 60mg in the morning. A couple hours after I took an over-the-country energy supplement (contains 'traces' of phenylalanine, which indirectly increases production of dopamine, adrenaline and noradrenaline - this may have contributed). I didn't eat that day after about 2pm. Around 7pm, I began feeling very dizzy and unwell, so I sat on a chair and tried to remain calm. I was noticeably tachycardic at this point, and within a few moments the rush hit me again. Extreme thirst, dizziness, static-like tunnel vision, chest pains, tremors, acute changes in temperature, intense tingling sensation. I fell to the floor, thinking I was having a heart attack. I may have lost consciousness briefly.

An ambulance was called, which took nearly an hour to arrive. In this time I slowly began to recover, though I sat in hospital all night still feeling disorientated. Multiple tests conducted (ECG, x-rays, blood, etc), and no explanation was found. Discharged the next morning, and a couple days later I was feeling fine.

Looking back, I know this was a panic attack; I have had a couple more since. Worryingly, this chemical seems to have altered my brain chemistry, as my body now reacts very badly to adrenaline. It is difficult to exercise or take any drugs (even alcohol) as any moderate adrenaline release causes tremors and dizziness, accompanied by fear and chest pains. I should also note that adrenaline now dilates my pupils a lot.
 
on a few occasions i've taken this stuff for extended periods for colds and viruses, maybe 2 weeks or 3 at the most. i've found that usually by week 2, i become very depressed and apathetic, and i feel "empty" inside, so i have to stop taking it. (plus, it kills erections. if you go to the hospital with priapism its one of the first things they give you.). its great for congestion though. i hope everything works out for you OP, try not taking any drugs for a little while and taking it easy in general, hopefully things will return to normal for you.
 
When I was working outside all day every day landscaping, my nose ran constantly, so I got in the habit of taking pseudoephedrine every day; 60mg in the morning and another 30-60 after lunch. After a while, it wasn't really even helping my runny nose, but I had gotten so used to that pick-me-up/energy, that I kept on taking it anyway. I never noticed any substantial adverse side effects, but I do recall feeling lethargic when I stopped taking it, as one would from ceasing use of any stimulant.

The worst aspect of regular pseudo use is that when you really need it for your sinuses, it won't work nearly as well as it could or should, if it works at all. Pseudoephedrine is a great medication; nothing works even half as well for drying and clearing out the sinuses.
 
i hope everything works out for you OP, try not taking any drugs for a little while and taking it easy in general, hopefully things will return to normal for you.

Oh, I'm not too bad now. After the initial panic attack I only had a couple more, which were caused by alcohol withdrawal (wasn't addicted, just had a severe hangover). It's been about three months now and I don't drink or take anything other than the odd sleeping pill, but I still have problems with adrenaline, ie. working out is very difficult and stressful.

Although it's hard to say if that was the first one - where would you draw the line between panic attack and bad acid trip? 8)
 
^When you're thinking you are experiencing tychardia and have intense bouts of panic because of it because you think you're close to dying. It's very close, as you said, to feeling like you're having a heart attack.

God damn panic attacks. I have the same issue with adrenaline-releasing drugs btw. I got it after 2 years of very irresponsible amphetamine use. It's been years and while the 'sober symptoms' are as good as gone, I still experience uppers completely different than I used to. I don't have panic attacks anymore, but I experience discomfort rather quickly on uppers.

I'm guessing that things should get better for you soon as you only took them for a relatively short time.

EDIT: facepalm to myself for replying to an ancient topic. Sorry. :|
 
It sounds to me like your "bad episodes" were periods of low blood pressure caused by stimulant rebound plus low blood sugar. Usually this happens when you change gait (stand up from a laying down position/sitting position) and results in the blood draining from the head and neck producing very strange sensations of unreality, dizziness, tunnel vision, "static", cold sweats etc. and in severe cases, total fainting and muscular spasms.

The fact that you hadn't eaten, and had been regularly using pseudo, supports this. Especially because there's no gorss physiological changes and it's transient (doesn't reoccur immediately). This is actually really common in some people - I get it when doctors poke my eyes, some people get it when they see blood. It's related to a vasovagal event, and I've also heard of it happening with cannabis users before.

The best way to prevent it is to make sure you have some food in your stomach, avoid overexertion, and if you feel your blood pressure drop, sit or lay down quickly to avoid fainting.

I wouldn't be outright scared of it, but if it happens frequently you should discontinue use. The worst thing that can happen is your b.p. drops and you drop to the floor and hit your head.
 
Also stay hydrated. Drink plenty of water or gatorade to prevent electrolyte imbalances and dehydration.

I can not take stims. I played with them the wrong way in my youth and now my body reacts badly to them. The most I can have is 1-2 cups of coffee.

If I accidentally take a stim I feel it and it is horrible for hours.
 
Same type of thing happened and happens to me from years of heavy cocaine and speed use ( 3.5g a night :( ).

Also I find if I smoke of Sativa heavy weed It can happen to me also, probably because the drugs changed my brain function (like you mentioned).

I really don't like any type of "upper" anymore since these experiences, so now I dabble in opiates and other "downers"

I had a severe panic attack on speed once, and I can tell you a panic attack is bad enough sober, so it was hell on speed. ;)
 
Are you me? :D ^

Seriously, reading that is like reading myself. Exactly the same happened to me. Long term speed addiction(1g++/day for years), I also turned to opiates and benzos because I was overly anxious after that.. Also had one panic attack after being awake for 3 nights on high doses of speed.

It all sounds so familiar.

Goodie that I'm off the opiates/oids & benzos now. Those things are even worse when you're getting off em.
 
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